Stephanopoulos:Projects

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Our research is focused on Metabolic Engineering - the improvement of cellular
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Our research is focused on Metabolic Engineering - the improvement of cellular properties, using modern genetic tools. This field encompasses two important components:
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properties, using modern genetic tools. This field encompasses two important components:
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<b>a)</b> the modification of biochemical pathways inside cells and
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<b>a)</b> the modification of biochemical pathways inside cells and <b>b)</b> the rigorous
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<b>b)</b> the rigorous evaluation of the resulting cellular phenotypes.
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evaluation of the resulting cellular phenotypes.
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  In recent years our group has investigated
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  Our most recent research has been focussed on the following topics:
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the following topics:
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                 <ul>
                 <ul>
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<li><b><a href="Coryne.shtml">Aminoacid biosynthesis in
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<li><b><a href="Biochemicals.shtml">Metabolic Engineering of <i>E.Coli</i>
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                <i>Corynebacterium glutamicum</i>.</b></a>  
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                for.</b></a> the production of biochemicals.
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<li><b><a href="Rhodo.shtml">Indene bioconversion in
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<li><b><a href="Inverse.shtml">Inverse Metabolic Engineering</b></a>
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<i>Rhodococcus </i>Sp.</b></a>
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<li><b><a href="Synecho.shtml">CO<sub>2</sub> fixation and
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<li><b><a href="gTME.shtml">gTME</b></a>
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product synthesis by the cyanobacterium <i>Synechocystis</i> Sp.</b></a>
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                 <li><b><a href="Diabetes.shtml">Elucidating type II diabetes by
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                 <li><b><a href="Flux.shtml">Flux Determination</b></a>
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                linking the expression and metabolic phenotypes of hepatoma and hepatocyte
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                cells.</b></a>
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<li><b><a href="Hepatocyte.shtml">Hepatocyte Physiology</b></a>
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<li><b><a href="Metabolomics.shtml">Metabolomics</b></a>
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<li><b><a href="SysBio.shtml">Systems Biology</b></a>
                 </ul>
                 </ul>
                  
                  

Revision as of 10:30, 12 July 2006

Research

Our research is focused on Metabolic Engineering - the improvement of cellular properties, using modern genetic tools. This field encompasses two important components: a) the modification of biochemical pathways inside cells and b) the rigorous evaluation of the resulting cellular phenotypes.


Our most recent research has been focussed on the following topics:

To accomplish the above goals we make use of a diverse array of scientific tools and methods, many of which have also become areas of research for our group:
Personal tools