Stephanopoulos:Projects
- the modification of biochemical pathways inside cells and
- the rigorous evaluation of the resulting cellular phenotypes.
- Metabolic Engineering of E.Coli for the production of biochemicals
- Inverse Metabolic Engineering
- gTME
- Flux Determination
- Hepatocyte Physiology
- Metabolomics
- Systems Biology
To accomplish the above goals we make use of a diverse array of scientific tools and methods, many of which have also become areas of research for our group:
- <a href="Bioinfo.shtml">Bioinformatics and Systems Biology</a> - Our group was one of the first to realize the importance of computational tools for handling the large volume of data generated by microarrays and other technologies.
- <a href="Fluxes.shtml">Methods for intracellular flux determination</a> - Fluxes are determined by material balancing, NMR fine spectra analysis and GC-MS measurements.
- <a href="Microarray.shtml">DNA microarrays</a> - We have developed full genome microarrays for Synechocystis Sp., and partial microarrays for C. glutamicum, E. coli, and the mouse genomes.
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<a href="BioReactor.shtml">Bioreaction network analysis.</a>
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<tr><td width=750 valign="top"> <!---Footer Info Table----> <table width=750 border=0 cellpadding=0 cellspacing=0> <tr><td align="left" width="250" valign="top"> <font color="maroon"><tt>Address</tt></font><br> <small> Massachusetts Institute of Technology<br> Department of Chemical Engineering<br> Cambridge, MA 02139<br> Room 56-469 </small> </td> <td align="center" width="250" valign="top"> <small> <a href="http://www.mit.edu">MIT</a> | <a href="/wiki/Stephanopoulos_Lab">HOME</a><br> Last Modified:<br>Monday, July 10th, 2006 - by <a href="Adrian.shtml">afi</a>. </small> <br> <font color="#990000"><tt>gnswebpage-www@mit.edu</tt></font> </td> <td align="right" width="250" valign="top"> <font color="#990000"><tt>Telephones</tt><br></font> <small> office | 617.258.0398<br> lab | 617.253.6591<br> lab | 617.258.0349<br> lab | 617.253.6521<br> fax | 617.253.3122<br> </small> </td></tr> </table></td></tr> </html>
