Streptomyces:Research

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Research Gabriella Kelemen Key Research Interests Our main research interest is studying bacterial development of Streptomyces coelicolor, a Gram-positive, filamentous bacterium. Unlike most bacteria that divide by binary fission, in Streptomyces coelicolor long, multigenomic filaments are formed with ocasional septa and regular branching. Cell division is completed only during sporulation when 50-100 sporulation septa are laid down synchronously in the aerial hyphae generating unigenomic spore compartments. Current projects include: ~ The role of specific RNA polymerase holoenzymes controlling development and stress response ~ Global characterisation of spore maturation and germination ~ Cytoskeletal proteins ~ Chromosome organisation during hyphal growth