|
|
| (201 intermediate revisions by 5 users not shown) |
| Line 1: |
Line 1: |
| [[SynBERC | back to SynBERC on OWW]] | | <wikionly><font size=1> < [[SynBERC]]</font></wikionly> |
| | | <nonwikionly>Visit the [http://openwetware.org/index.php?title=SynBERC:MIT wiki version of this page].</nonwikionly> |
|
| |
|
| ==SynBERC Research @ MIT== | | ==SynBERC Research @ MIT== |
| [[SynBERC:MIT/Researchers | MIT SynBERC Research Projects]] | | [[SynBERC:MIT/Researchers | Short summaries of MIT SynBERC research projects]]. |
|
| |
|
| ==Lab Video Tours== | | ==Lab Video Tours== |
| [[SynBERC:MIT/Lab video tours|MIT Lab video tours]] | | [[SynBERC:MIT/Lab video tours|MIT lab video tours]] |
|
| |
|
| ==Synthetic Biology Working Group lunches== | | ==Synthetic Biology Working Group lunches== |
| | Current information about SBWG Lunches is located at [[SBWGLunches]]. |
|
| |
|
| <font color=red>'''SBWG lunch will be held on Tuesdays at 12pm during the spring term. Apologies to those who can't make it!'''</font>
| | Information pre-2010 can be found at [[SynBERC:SBWGLunchesArchive]]. |
| | |
| ===Overview===
| |
| Synthetic Biology Working Group lunches are an opportunity for anyone in the Boston-area who is interested in synthetic biology to get together and discuss current issues and topics in the field. Each lunch discussion is led by someone (selected at the end of lunch the previous week) and focuses on a particular topic. The style of the lunch is really meant to be a ''discussion'' rather than a presentation. Therefore, discussion leaders frequently give a chalk talk or only have a handful of slides to help structure discussion.
| |
| | |
| Announcements regarding Synthetic Biology Working Group lunches are sent to synthbio AT mit. To join the mailing list, go [https://ca.mit.edu/moira/index.jhtml here] or contact [[Isadora Deese]]. All are welcome to attend.
| |
| | |
| '''If you've previously led a discussion at SBWG lunch, please consider posting your slides or notes at the appropriate link below.'''
| |
| | |
| ===Next meeting===
| |
| *[[SynBERC:MIT/Calendar/2007-3-6]]: 21th of restarted MIT SBWG lunch
| |
| **Tuesday 3/6 (12-1p), [http://whereis.mit.edu/map-jpg?mapterms=32&mapsearch=go 32]-[http://www.csail.mit.edu/resources/maps/4G/G449.gif G449], MIT
| |
| | |
| *March 13 - maybe Broad visit
| |
| *March 20 - Likely education (best for Natalie)
| |
| *April 10 - Fran Perler, inteins, NEB
| |
| | |
| <showhide>
| |
| ===Previous meetings===
| |
| __HIDER__
| |
| <hide>
| |
| *[[SynBERC:MIT/Calendar/2007-2-27]]: 20th of restarted MIT SBWG lunch
| |
| **Tuesday 2/27 (12-1p), [http://whereis.mit.edu/map-jpg?mapterms=32&mapsearch=go 32]-[http://www.csail.mit.edu/resources/maps/4G/G449.gif G449], MIT
| |
| *[[SynBERC:MIT/Calendar/2007-2-13]]: 19th of restarted MIT SBWG lunch
| |
| **Tuesday 2/13 (12-1p), 68-181, MIT
| |
| *[[SynBERC:MIT/Calendar/2007-2-6]]: 18th of restarted MIT SBWG lunch
| |
| **Tuesday 2/6 (12-1p), [http://whereis.mit.edu/map-jpg?mapterms=32&mapsearch=go 32]-[http://www.csail.mit.edu/resources/maps/4G/G449.gif G449], MIT
| |
| *[[SynBERC:MIT/Calendar/2007-1-31]]: 17th of restarted MIT SBWG lunch
| |
| **Wednesday 1/31 (1-2p), [http://whereis.mit.edu/map-jpg?mapterms=32&mapsearch=go 32]-[http://www.csail.mit.edu/resources/maps/4G/G449.gif G449], MIT
| |
| *[[SynBERC:MIT/Calendar/2007-1-24]]: 16th of restarted MIT SBWG lunch
| |
| **Wednesday 1/24 (1-2p), 56-614, MIT
| |
| *[[SynBERC:MIT/Calendar/2007-1-17]]: 15th of restarted MIT SBWG lunch
| |
| **Wednesday 1/17 (1-2p), 56-614, MIT
| |
| *[[SynBERC:MIT/Calendar/2007-1-10]]: 14th of restarted MIT SBWG lunch
| |
| **Wednesday 1/10 (1-2p), 32-G449, MIT
| |
| *[[SynBERC:MIT/Calendar/2006-12-20]]: 13th of restarted MIT SBWG lunch
| |
| **Wednesday 12/20 (1-2p), 68-180, MIT
| |
| *[[SynBERC:MIT/Calendar/2006-12-13]]: 12th of restarted MIT SBWG lunch
| |
| **Wednesday 12/13 (1-2p), 68-180, MIT
| |
| *[[SynBERC:MIT/Calendar/2006-12-6]]: 11th of restarted MIT SBWG lunch
| |
| **Wednesday 12/06 (1-2p), 68-180, MIT
| |
| *[[SynBERC:MIT/Calendar/2006-11-29]]: 10th of restarted MIT SBWG lunch
| |
| **Wednesday 11/29 (1-2p), 68-180, MIT
| |
| *[[SynBERC:MIT/Calendar/2006-11-15]]: 9th of restarted MIT SBWG lunch
| |
| **Wednesday 11/15 (1-2p), 68-180, MIT
| |
| *[[SynBERC:MIT/Calendar/2006-11-08]]: 8th of restarted MIT SBWG lunch
| |
| **Wednesday 11/08 (1-2p), 68-180, MIT
| |
| *[[SynBERC:MIT/Calendar/2006-11-01]]: 7th of restarted MIT SBWG lunch
| |
| **Wednesday 11/01 (1-2p), 32-G449, MIT
| |
| *[[SynBERC:MIT/Calendar/2006-10-25]]: 6th of restarted MIT SBWG lunch
| |
| **Wednesday 10/25 (1-2p), 32-G449, MIT
| |
| *[[SynBERC:MIT/Calendar/2006-10-18]]: 5th of restarted MIT SBWG lunch
| |
| **Wednesday 10/18 (1-2p), 68-180, MIT
| |
| *[[SynBERC:MIT/Calendar/2006-10-11]]: 4th of restarted MIT SBWG lunch
| |
| **Wednesday 10/11 (1-2p), 32-G449 (Kiva conference room), MIT
| |
| *[[SynBERC:MIT/Calendar/2006-10-4]]: 3rd of restarted MIT SBWG lunch
| |
| **Wednesday 10/4 (1-2p), 68-180, MIT
| |
| *[[SynBERC:MIT/Calendar/2006-9-27]]: 2nd of restarted MIT SBWG lunch
| |
| **Wednesday 9/27 (1-2p), 32-D463, MIT
| |
| *[[SynBERC:MIT/Calendar/2006-9-20]]: 1st of restarted MIT SBWG lunch
| |
| **Wednesday 9/20 (1-2p), 32-G449
| |
| **Please feel free to add yourself to the agenda.
| |
| *[[SynBERC:MIT/Calendar/2006-8-30]]: Kickoff Meeting @ MIT
| |
| **Wednesday 8/30 (4-5p), 68-574 or immediately local surrogate
| |
| </hide>
| |
| </showhide>
| |
| | |
| ==Proposed topics==
| |
| Some potential topics to be discussed at MIT SBWG lunch ... just brainstorming ... please edit. (I know that we had talked about having people present but I think there are also a set of issues that several people's projects touch on but aren't being addressed by any one person.) Apologies because these aren't articulated very well.
| |
| | |
| #Electronics device families (introduction by TK) - [[SynBERC:MIT/Calendar/2006-9-27]]
| |
| #Abstraction hierarchies
| |
| ##Parts -> Devices -> Systems
| |
| ##Biological layer model (AC)
| |
| #'''DEVICES''': Composability? Device family specification? Interfaces within families? Interfaces across families? Eventually parts datasheet? Eventually standards?
| |
| ##Transcriptional device families (RS and CAF) - [[SynBERC:MIT/Calendar/2006-10-4]], [[SynBERC:MIT/Calendar/2006-10-11]]
| |
| ##Post-translational device families (SS) - [[SynBERC:MIT/Calendar/2007-2-13]]
| |
| ##Biosynthetic device families (KJP lab) - [[SynBERC:MIT/Calendar/2006-10-18]], [[SynBERC:MIT/Calendar/2006-10-25]]
| |
| ##Ribozyme device families (AC) - [[SynBERC:MIT/Calendar/2007-1-10]], [[SynBERC:MIT/Calendar/2007-1-17]] and [[SynBERC:MIT/Calendar/2007-1-24]]
| |
| ##Translation device families?
| |
| #'''PARTS''': [[SynBERC:MIT/Calendar/2007-2-6]]
| |
| ##Terminators
| |
| ##Coding regions
| |
| ##RBSs
| |
| ##Promoters
| |
| ##Composability and characterization - [[SynBERC:MIT/Calendar/2006-11-01]]
| |
| #'''CHASSIS''': Why do we want different kinds? What kinds? What are the simplest systems that work?
| |
| ##Minimal chassis
| |
| ##Mesoplasma florum - [[SynBERC:MIT/Calendar/2006-12-13]]
| |
| ##E. coli standard strain and rE. coli - [[SynBERC:MIT/Calendar/2006-12-6]]
| |
| ##Yeast
| |
| ##Power supply - [[SynBERC:MIT/Calendar/2006-11-15]]
| |
| ##Vectors - [[SynBERC:MIT/Calendar/2007-1-31]]
| |
| #Synthesis technologies
| |
| ##What is state of the art?
| |
| ##What are the good ideas?
| |
| ##How do we get more investment?
| |
| ##Can the fabs constrain what people synthesize?
| |
| #What does the CAD tool look like?
| |
| #Human practice
| |
| #Differentiation and cell to cell communication. Development. Programmed pattern formation. (Arthur Lander, Radhika)
| |
| #[[Synthetic Biology:BioBricks/Standardization|Standards]] (also see talk page)
| |
| #Load issues
| |
| #*What demands on the chassis are of most concern to us? Replication, transcription, [[Endy:Translation demand|translation]], Enzyme activity?
| |
| #**Are we regularly placing high demands on the chassis with our existing systems?
| |
| #*What chassis responses to an applied demand are of relevance? Growth rate, protein synthesis capacity?
| |
| #**Can we specify a threshold demand level above which the chassis response is so severe as to render the our engineered systems inoperable?
| |
| #Selection against our systems [[SynBERC:MIT/Calendar/2006-12-20]]
| |
| ##e.g. IS elements are showing up in our devices!
| |
| #Statistics of codon pairs (UC Irvine folks)
| |
| #iGEM 2010 - [[SynBERC:MIT/Calendar/2006-11-08]]
| |
| #Registry 2.0
| |
| #Publishing (with CS on Oct 20) - held separately
| |
| #Controlled transcriptional termination as an implementation for logic - Chris Anderson
| |
| #Designing enzymatic reactions by splitting catalytic activity and substrate specificity potentially by scaffolds - John Dueber? ask Adam Arkin for someone to talk about this
| |
| #What is the obvious list of things to do?
| |
| ##Parts characterization
| |
| ##How do we get basic tasks done?
| |
| #Experience with different parts: RBSs, promoters, terminators - Jen? Chris Anderson? Curt and Hal Alper
| |
| #Web of registries - Randy
| |
| #Repetitive sequences and potential for recombination - ask Graham Walker, someone in Philadelphia
| |
| #Registry of models - Barry and Vincent
| |
| #Bacterial counter and how you implement it - Tom or Gerry
| |
| #How do I get a computer inside my cell? - Tom
| |
| #Human practices - Michael Rossi
| |
| #Writing DNA - Maia, Farren?, Church lab, Adam Arkin, Sasha and polony sequencing
| |
| #Noncoding RNAs - Ron Breaker
| |
| #Materials - Angie Belcher
| |
| #Education in SB - Natalie and Scot and Austin and Michael and Shawn?
| |
| ##Curriculum
| |
| ##Workshop implementation
| |
| ##Materials
| |
| ##Bootcamp
| |
| #Security - are we ok with the current investments in biotechnology? - Drew, Gautam? Phil Sharp and Gerry Fink and Jonathan King and Noam Chomsky and Ed Hammond
| |
| #*Must act in the absence of perfect knowledge
| |
| #Impact of big pharma and big ag and big energy on our field
| |
| #Inteins and Fran Perler from NEB
| |
| #Brian Baynes and Codon Devices - future of DNA synthesis technology
| |
| #Please add your topic to the list.
| |
| | |
| ==Spring room schedule==
| |
| SBWG lunch will be on Tuesdays at 12pm during the spring term. If the timing doesn't work for you, please let [[Reshma Shetty|Reshma]] know.
| |
| | |
| ===Room reservations===
| |
| All lunches except those below will be in Kiva, [http://whereis.mit.edu/map-jpg?mapterms=32&mapsearch=go 32]-[http://www.csail.mit.edu/resources/maps/4G/G449.gif G449], MIT beginning February 6, 2007 and ending May 31, 2007.
| |
| | |
| *February 13 - 68-181
| |
| *April 24 - 68-181 (must end by 1pm)
| |
