|
|
(286 intermediate revisions by 10 users not shown) |
Line 1: |
Line 1: |
| [[SynBERC | back to SynBERC on OWW]] | | <wikionly><font size=1> < [[SynBERC]]</font></wikionly> |
| | <nonwikionly>Visit the [http://openwetware.org/index.php?title=SynBERC:MIT wiki version of this page].</nonwikionly> |
| | |
| | ==SynBERC Research @ MIT== |
| | [[SynBERC:MIT/Researchers | Short summaries of MIT SynBERC research projects]]. |
|
| |
|
| ==Lab Video Tours== | | ==Lab Video Tours== |
| [[SynBERC:MIT/Lab video tours|MIT Lab video tours]] | | [[SynBERC:MIT/Lab video tours|MIT lab video tours]] |
| | |
| ==Meetings==
| |
| *[[SynBERC:MIT/Calendar/2006-9-20]]: First of restarted MIT SBWG lunch
| |
| **Wednesday 9/20 (1-2p), 32-G449
| |
| **Please feel free to add yourself to the agenda.
| |
| *[[SynBERC:MIT/Calendar/2006-8-30]]: Kickoff Meeting @ MIT
| |
| **Wednesday 8/30 (4-5p), 68-574 or immediately local surrogate
| |
|
| |
|
| ==Proposed topics== | | ==Synthetic Biology Working Group lunches== |
| Some potential topics to be discussed at MIT SBWG lunch ... just brainstorming ... please edit. (I know that we had talked about having people present but I think there are also a set of issues that several people's projects touch on but aren't being addressed by any one person.) Apologies because these aren't articulated very well.
| | Current information about SBWG Lunches is located at [[SBWGLunches]]. |
|
| |
|
| ===Topics===
| | Information pre-2010 can be found at [[SynBERC:SBWGLunchesArchive]]. |
| #Electronics device families (introduction by TK)
| |
| #Abstraction hierarchies
| |
| ##Parts -> Devices -> Systems
| |
| ##Biological layer model (AC)
| |
| #'''DEVICES''': Composability? Device family specification? Interfaces within families? Interfaces across families? Eventually parts datasheet? Eventually standards?
| |
| ##Transcriptional device families
| |
| ##Post-translational device families (SS)
| |
| ##Biosynthetic device families (KJP lab)
| |
| ##Ribozyme device families (AC)
| |
| ##Translation device families?
| |
| #'''PARTS''':
| |
| ##Terminators
| |
| ##Coding regions
| |
| ##RBSs
| |
| ##Promoters
| |
| #'''CHASSIS''': Why do we want different kinds? What kinds? What are the simplest systems that work?
| |
| #Synthesis technologies
| |
| ##What is state of the art?
| |
| ##What are the good ideas?
| |
| ##How do we get more investment?
| |
| ##Can the fabs constrain what people synthesize?
| |
| #What does the CAD tool look like?
| |
| #Human practices
| |
| #Differentiation and cell to cell communication. Development. Programmed pattern formation. Arthur Lander. Radhika.
| |
| #[[Synthetic Biology:BioBricks/Standardization|Standards]] (also see talk page)
| |
| #What characteristics are necessary for a standard specification of part/device/system function? i.e. what does the part datasheet look like?
| |
| #*What are the important characteristics for a device that catalyzes an enzymatic reaction?
| |
| #*What are the important characteristics for a transcription based device?
| |
| #**Here is one [[Endy:F2620|proposal]].
| |
| #Load issues
| |
| #*What demands on the chassis are of most concern to us? Replication, transcription, [[Endy:Translation demand|translation]], Enzyme activity?
| |
| #**Are we regularly placing high demands on the chassis with our existing systems?
| |
| #*What chassis responses to an applied demand are of relevance? Growth rate, protein synthesis capacity?
| |
| #**Can we specify a threshold demand level above which the chassis response is so severe as to render the our engineered systems inoperable?
| |
| #Selection against our systems
| |
| ##e.g. IS elements are showing up in our devices!
| |
| #Standard chassis
| |
| #Statistics of codon pairs
| |
| #iGEM 2010
| |
| #Registry 2.0
| |
| #Publishing (with CS on Oct 20)
| |
| #Please add your topic to the list.
| |