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| [[SynBERC | back to SynBERC on OWW]] | | <wikionly><font size=1> < [[SynBERC]]</font></wikionly> |
| | | <nonwikionly>Visit the [http://openwetware.org/index.php?title=SynBERC:MIT wiki version of this page].</nonwikionly> |
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| ==SynBERC Research @ MIT== | | ==SynBERC Research @ MIT== |
| [[SynBERC:MIT/Researchers | MIT SynBERC Research Projects]] | | [[SynBERC:MIT/Researchers | Short summaries of MIT SynBERC research projects]]. |
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| ==Lab Video Tours== | | ==Lab Video Tours== |
| [[SynBERC:MIT/Lab video tours|MIT Lab video tours]] | | [[SynBERC:MIT/Lab video tours|MIT lab video tours]] |
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| ==Meetings==
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| *[[SynBERC:MIT/Calendar/2006-9-27]]: Second of restarted MIT SBWG lunch
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| **Wednesday 9/27 (1-2p), 32-G449 (unless someone finds another room)
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| *[[SynBERC:MIT/Calendar/2006-9-20]]: First of restarted MIT SBWG lunch
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| **Wednesday 9/20 (1-2p), 32-G449
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| **Please feel free to add yourself to the agenda.
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| *[[SynBERC:MIT/Calendar/2006-8-30]]: Kickoff Meeting @ MIT
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| **Wednesday 8/30 (4-5p), 68-574 or immediately local surrogate
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| ==Scheduling constraints==
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| *Transcriptional device family before Nov 1 (CMC)
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| *Biosynthetic device family between Oct 11 and Nov 1 inclusive (KJP)
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| ==Proposed topics== | | ==Synthetic Biology Working Group lunches== |
| Some potential topics to be discussed at MIT SBWG lunch ... just brainstorming ... please edit. (I know that we had talked about having people present but I think there are also a set of issues that several people's projects touch on but aren't being addressed by any one person.) Apologies because these aren't articulated very well.
| | Current information about SBWG Lunches is located at [[SBWGLunches]]. |
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| #Electronics device families (introduction by TK) - [[SynBERC:MIT/Calendar/2006-9-27]]
| | Information pre-2010 can be found at [[SynBERC:SBWGLunchesArchive]]. |
| #Abstraction hierarchies
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| ##Parts -> Devices -> Systems
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| ##Biological layer model (AC)
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| #'''DEVICES''': Composability? Device family specification? Interfaces within families? Interfaces across families? Eventually parts datasheet? Eventually standards?
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| ##Transcriptional device families
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| ##Post-translational device families (SS)
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| ##Biosynthetic device families (KJP lab)
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| ##Ribozyme device families (AC)
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| ##Translation device families?
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| #'''PARTS''':
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| ##Terminators
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| ##Coding regions
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| ##RBSs
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| ##Promoters
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| #'''CHASSIS''': Why do we want different kinds? What kinds? What are the simplest systems that work?
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| ##Minimal chassis
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| ##Mesoplasma florum
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| ##E. coli standard strain and rE. coli
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| ##Yeast
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| #Synthesis technologies
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| ##What is state of the art?
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| ##What are the good ideas?
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| ##How do we get more investment?
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| ##Can the fabs constrain what people synthesize?
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| #What does the CAD tool look like?
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| #Human practice
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| #Differentiation and cell to cell communication. Development. Programmed pattern formation. (Arthur Lander, Radhika)
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| #[[Synthetic Biology:BioBricks/Standardization|Standards]] (also see talk page)
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| #Load issues
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| #*What demands on the chassis are of most concern to us? Replication, transcription, [[Endy:Translation demand|translation]], Enzyme activity?
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| #**Are we regularly placing high demands on the chassis with our existing systems?
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| #*What chassis responses to an applied demand are of relevance? Growth rate, protein synthesis capacity?
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| #**Can we specify a threshold demand level above which the chassis response is so severe as to render the our engineered systems inoperable?
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| #Selection against our systems
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| ##e.g. IS elements are showing up in our devices!
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| #Statistics of codon pairs (UC Irvine folks)
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| #iGEM 2010
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| #Registry 2.0
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| #Publishing (with CS on Oct 20)
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| #Please add your topic to the list.
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