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Synthetic Biology Working Group lunches

SBWG lunch will be held on Tuesdays at 12pm during the spring term. Apologies to those who can't make it!

Overview

Synthetic Biology Working Group lunches are an opportunity for anyone in the Boston-area who is interested in synthetic biology to get together and discuss current issues and topics in the field. Each lunch discussion is led by someone (selected at the end of lunch the previous week) and focuses on a particular topic. The style of the lunch is really meant to be a discussion rather than a presentation. Therefore, discussion leaders frequently give a chalk talk or only have a handful of slides to help structure discussion.

Announcements regarding Synthetic Biology Working Group lunches are sent to synthbio AT mit. To join the mailing list, go here or contact Isadora Deese. All are welcome to attend.

If you've previously led a discussion at SBWG lunch, please consider posting your slides or notes at the appropriate link below.

Next meeting

• SynBERC:MIT/Calendar/2007-2-6: 18th of restarted MIT SBWG lunch
  • Tuesday 2/6 (1-2p), 32-G449, MIT

Previous meetings

• SynBERC:MIT/Calendar/2007-1-31: 17th of restarted MIT SBWG lunch
  • Wednesday 1/31 (1-2p), 32-G449, MIT
• SynBERC:MIT/Calendar/2007-1-24: 16th of restarted MIT SBWG lunch
  • Wednesday 1/24 (1-2p), 56-614, MIT
• SynBERC:MIT/Calendar/2007-1-17: 15th of restarted MIT SBWG lunch
  • Wednesday 1/17 (1-2p), 56-614, MIT
• SynBERC:MIT/Calendar/2007-1-10: 14th of restarted MIT SBWG lunch
  • Wednesday 1/10 (1-2p), 32-G449, MIT
• SynBERC:MIT/Calendar/2006-12-20: 13th of restarted MIT SBWG lunch
  • Wednesday 12/20 (1-2p), 68-180, MIT
• SynBERC:MIT/Calendar/2006-12-13: 12th of restarted MIT SBWG lunch
  • Wednesday 12/13 (1-2p), 68-180, MIT
• SynBERC:MIT/Calendar/2006-12-6: 11th of restarted MIT SBWG lunch
  • Wednesday 12/06 (1-2p), 68-180, MIT
• SynBERC:MIT/Calendar/2006-11-29: 10th of restarted MIT SBWG lunch
  • Wednesday 11/29 (1-2p), 68-180, MIT
• SynBERC:MIT/Calendar/2006-11-15: 9th of restarted MIT SBWG lunch
  • Wednesday 11/15 (1-2p), 68-180, MIT
• SynBERC:MIT/Calendar/2006-11-08: 8th of restarted MIT SBWG lunch
  • Wednesday 11/08 (1-2p), 68-180, MIT
• SynBERC:MIT/Calendar/2006-11-01: 7th of restarted MIT SBWG lunch
  • Wednesday 11/01 (1-2p), 32-G449, MIT
• SynBERC:MIT/Calendar/2006-10-25: 6th of restarted MIT SBWG lunch
  • Wednesday 10/25 (1-2p), 32-G449, MIT
• SynBERC:MIT/Calendar/2006-10-18: 5th of restarted MIT SBWG lunch
  • Wednesday 10/18 (1-2p), 68-180, MIT
• SynBERC:MIT/Calendar/2006-10-11: 4th of restarted MIT SBWG lunch
  • Wednesday 10/11 (1-2p), 32-G449 (Kiva conference room), MIT
• SynBERC:MIT/Calendar/2006-10-4: 3rd of restarted MIT SBWG lunch
  • Wednesday 10/4 (1-2p), 68-180, MIT
• SynBERC:MIT/Calendar/2006-9-27: 2nd of restarted MIT SBWG lunch
  • Wednesday 9/27 (1-2p), 32-D463, MIT
• SynBERC:MIT/Calendar/2006-9-20: 1st of restarted MIT SBWG lunch
  • Wednesday 9/20 (1-2p), 32-G449
  • Please feel free to add yourself to the agenda.
• SynBERC:MIT/Calendar/2006-8-30: Kickoff Meeting @ MIT
  • Wednesday 8/30 (4-5p), 68-574 or immediately local surrogate

Proposed topics

Some potential topics to be discussed at MIT SBWG lunch ... just brainstorming ... please edit. (I know that we had talked about having people present but I think there are also a set of issues that several people's projects touch on but aren't being addressed by any one person.) Apologies because these aren't articulated very well.

1. Electronics device families (introduction by TK) - SynBERC:MIT/Calendar/2006-9-27
2. Abstraction hierarchies
   1. Parts -> Devices -> Systems
   2. Biological layer model (AC)
3. DEVICES: Composability? Device family specification? Interfaces within families? Interfaces across families? Eventually parts datasheet? Eventually standards?
   1. Transcriptional device families (RS and CAF) - SynBERC:MIT/Calendar/2006-10-4, SynBERC:MIT/Calendar/2006-10-11
   2. Post-translational device families (SS)
   3. Biosynthetic device families (KJP lab) - SynBERC:MIT/Calendar/2006-10-18, SynBERC:MIT/Calendar/2006-10-25
   4. Ribozyme device families (AC) - SynBERC:MIT/Calendar/2006-1-10, SynBERC:MIT/Calendar/2006-1-17 and SynBERC:MIT/Calendar/2006-1-24
   5. Translation device families?
4. PARTS: SynBERC:MIT/Calendar/2006-2-7
   1. Terminators
   2. Coding regions
   3. RBSs
   4. Promoters
   5. Composability and characterization - SynBERC:MIT/Calendar/2006-11-01
5. CHASSIS: Why do we want different kinds? What kinds? What are the simplest systems that work?
   1. Minimal chassis
   2. Mesoplasma florum - SynBERC:MIT/Calendar/2006-12-13
   3. E. coli standard strain and rE. coli - SynBERC:MIT/Calendar/2006-12-6
   4. Yeast
   5. Power supply - SynBERC:MIT/Calendar/2006-11-15
   6. Vectors - SynBERC:MIT/Calendar/2006-1-31
6. Synthesis technologies
   1. What is state of the art?
   2. What are the good ideas?
   3. How do we get more investment?
   4. Can the fabs constrain what people synthesize?
7. What does the CAD tool look like?
8. Human practice
9. Differentiation and cell to cell communication. Development. Programmed pattern formation. (Arthur Lander, Radhika)
10. Standards (also see talk page)
11. Load issues
    • What demands on the chassis are of most concern to us? Replication, transcription, translation, Enzyme activity?
      • Are we regularly placing high demands on the chassis with our existing systems?
    • What chassis responses to an applied demand are of relevance? Growth rate, protein synthesis capacity?
      • Can we specify a threshold demand level above which the chassis response is so severe as to render the our engineered systems inoperable?
12. Selection against our systems SynBERC:MIT/Calendar/2006-12-20
    1. e.g. IS elements are showing up in our devices!
13. Statistics of codon pairs (UC Irvine folks)
14. iGEM 2010 - SynBERC:MIT/Calendar/2006-11-08
15. Registry 2.0
16. Publishing (with CS on Oct 20) - held separately
17. Please add your topic to the list.

Spring room schedule

SBWG lunch will be on Tuesdays at 12pm during the spring term. If the timing doesn't work for you, please let Reshma know.

Room reservations

All lunches except those below will be in Kiva, 32-G449, MIT beginning February 6, 2007 and ending May 31, 2007.

• February 17 - pending
• April 24 - pending