SynBERC:Seminar series/Remy Chait: Difference between revisions
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A video stream of the talk will be available for real-time viewing. Just point Quicktime or [http://www.videolan.org/vlc/ VLC] to the following stream: | A video stream of the talk will be available for real-time viewing. Just point Quicktime or [http://www.videolan.org/vlc/ VLC] to the following stream: | ||
'''rtsp://caprica.csail.mit.edu/SynBERC.sdp''' | '''rtsp://caprica.csail.mit.edu/SynBERC.sdp''' | ||
===Archived video=== | |||
A copy of the talk is available at [http://blip.tv/file/210435 blip.tv]. It is also embedded below (follow the previous link to blip.tv for other formats): | |||
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<center> <script type="text/javascript" src="http://blip.tv/scripts/pokkariPlayer.js"></script><script type="text/javascript" src="http://blip.tv/syndication/write_player?skin=js&posts_id=214769&source=3&autoplay=true&file_type=mov&player_width=0&player_height=0"></script><div id="blip_movie_content_214769"><a href="http://blip.tv/file/get/Synberc-SynBERCSeminarSeriesRemyChait24April2007819.mp4" onclick="play_blip_movie_214769(); return false;"><img src="http://blip.tv/file/get/Synberc-SynBERCSeminarSeriesRemyChait24April2007819.mp4.jpg" border="0" title="Click To Play" /></a><br /><a href="http://blip.tv/file/get/Synberc-SynBERCSeminarSeriesRemyChait24April2007819.mp4" onclick="play_blip_movie_214769(); return false;">Click To Play</a></div> </center> | |||
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Revision as of 04:29, 26 April 2007
Antibacterial drug combinations and evolution of drug resistance
Remy Chait, Harvard Systems Biology
April 24, 2007
12-1pm
68-181, MIT
The rapid evolution of bacterial drug resistance and the alarming slowdown in development of new antibiotics is spurring attention towards multi-drug treatments. But how do such treatments affect the rate of evolution of drug resistance? I will present a simple model and direct experimental measurements showing that non-additive interactions between the drugs can profoundly alter the fitness landscape, leading to surprising and counterintuitive outcomes.
Reference
- Chait R, Craney A, and Kishony R. Antibiotic interactions that select against resistance. Nature. 2007 Apr 5;446(7136):668-71. DOI:10.1038/nature05685 |
Remote participation
To submit questions during the talk, you must have an OpenWetWare account. Type questions into the chat room.
A video stream of the talk will be available for real-time viewing. Just point Quicktime or VLC to the following stream:
rtsp://caprica.csail.mit.edu/SynBERC.sdp
Archived video
A copy of the talk is available at blip.tv. It is also embedded below (follow the previous link to blip.tv for other formats):
<html> <center> <script type="text/javascript" src="http://blip.tv/scripts/pokkariPlayer.js"></script><script type="text/javascript" src="http://blip.tv/syndication/write_player?skin=js&posts_id=214769&source=3&autoplay=true&file_type=mov&player_width=0&player_height=0"></script><div id="blip_movie_content_214769"><a href="http://blip.tv/file/get/Synberc-SynBERCSeminarSeriesRemyChait24April2007819.mp4" onclick="play_blip_movie_214769(); return false;"><img src="http://blip.tv/file/get/Synberc-SynBERCSeminarSeriesRemyChait24April2007819.mp4.jpg" border="0" title="Click To Play" /></a><br /><a href="http://blip.tv/file/get/Synberc-SynBERCSeminarSeriesRemyChait24April2007819.mp4" onclick="play_blip_movie_214769(); return false;">Click To Play</a></div> </center> </html>