SynBERC:Tumors: Difference between revisions
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== Environmental Sensors == | == Environmental Sensors == | ||
Endogeneous promoters sensitive to the different environments may be discovered by microarray analysis, or RIVET-like analysis of cells grown in the appropriate environments. These will need spec sheets made for them. However, how one makes pluggable, dynamic range tunable, synthetic systems for sensing is still and open question. | |||
=== Serum === | === Serum === | ||
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==Actuators== | ==Actuators== | ||
Revision as of 13:33, 30 August 2006
Tumor Killing Bacterium Devices
Contacts: J. Christopher Anderson, Adam Paul Arkin, Christopher Voigt
Environmental Sensors
Endogeneous promoters sensitive to the different environments may be discovered by microarray analysis, or RIVET-like analysis of cells grown in the appropriate environments. These will need spec sheets made for them. However, how one makes pluggable, dynamic range tunable, synthetic systems for sensing is still and open question.
Serum
Tissue
Tumor
- Tumor Antigen Touch Sensor
Intracellular
Actuators
Immune Shielding
- K-Capsule Engineering
Growth Control
- Iron Uptake Engineering
Cell Attachment/Invasion
- Invasin Engineering
Cell Motility in the Extra- and Intracellular Environments
Synthesis and Delivery of Therapeutics
- Type III Secretion Engineering
Safety
Metabolic Auxotrophies
- DAP Engineering
Programmed Suicide Systems
Chemical Sensitivities
Mutational Control
Control
Multi-input Genetic Logic Gates
- Genetic Two-Input AND
Memory Systems
- Invertible Switch Engineering
Signal Pathway Logic
- Signaling Scaffold Engineering
Timers
Instrumentation
- Expressible anoxic fluorophors
- molecular beacons for transcript monitoring