SynBERC:Tumors: Difference between revisions
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m (Tumor Destroying Bacterium Devices moved to SynBERC:Tumors: move into the SynBERC namespace ... please revert if you don't like the new name) |
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[http://openwetware.org/wiki/SynBERC ->back to main<-] [http://openwetware.org/wiki/SynBERC:Devices ->back to devices<-] [[SynBERC:TKB|back to TKB]] | |||
= Tumor Killing Bacterium Devices = | = Tumor Killing Bacterium Devices = | ||
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<div style="background:#99ff99; color:#000000; width:840px; border: 1px outset black;"> | <div style="background:#99ff99; color:#000000; width:840px; border: 1px outset black;"> | ||
== Environmental Sensors == | == Environmental Sensors == | ||
Endogeneous promoters sensitive to the different environments may be discovered by microarray analysis, or RIVET-like analysis of cells grown in the appropriate environments. These will need spec sheets made for them. However, how one makes pluggable, dynamic range tunable, synthetic systems for sensing is still an open question. | |||
=== Serum === | === Serum === | ||
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<div style="background:#ffff99; color:#000000; width:840px; border: 1px outset black;"> | <div style="background:#ffff99; color:#000000; width:840px; border: 1px outset black;"> | ||
==Actuators== | ==Actuators== | ||
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=== Cell Attachment/Invasion === | === Cell Attachment/Invasion === | ||
*Modified pili | |||
*Invasin Engineering | *Invasin Engineering | ||
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=== Synthesis and Delivery of Therapeutics === | === Synthesis and Delivery of Therapeutics === | ||
* Type III Secretion Engineering | * Type III Secretion Engineering | ||
* Endocytic vacuole lysis | |||
</div> | </div> | ||
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===Multi-input Genetic Logic Gates === | ===Multi-input Genetic Logic Gates === | ||
* Genetic Two-Input AND | * Genetic Two-Input AND | ||
* A multi-input signal integrator | |||
* Inverters | |||
===Memory Systems=== | ===Memory Systems=== | ||
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===Timers=== | ===Timers=== | ||
</div> | |||
<div style="background:#BBBBBB; color:#000000; width:840px; border: 1px outset black;"> | |||
==Instrumentation== | |||
* Expressible anoxic fluorophors | |||
* molecular beacons for transcript monitoring | |||
</div> | </div> | ||
Latest revision as of 09:53, 7 October 2006
->back to main<- ->back to devices<- back to TKB
Tumor Killing Bacterium Devices
Contacts: J. Christopher Anderson, Adam Paul Arkin, Christopher Voigt
Environmental Sensors
Endogeneous promoters sensitive to the different environments may be discovered by microarray analysis, or RIVET-like analysis of cells grown in the appropriate environments. These will need spec sheets made for them. However, how one makes pluggable, dynamic range tunable, synthetic systems for sensing is still an open question.
Serum
Tissue
Tumor
- Tumor Antigen Touch Sensor
Intracellular
Actuators
Immune Shielding
- K-Capsule Engineering
Growth Control
- Iron Uptake Engineering
Cell Attachment/Invasion
- Modified pili
- Invasin Engineering
Cell Motility in the Extra- and Intracellular Environments
Synthesis and Delivery of Therapeutics
- Type III Secretion Engineering
- Endocytic vacuole lysis
Safety
Metabolic Auxotrophies
- DAP Engineering
Programmed Suicide Systems
Chemical Sensitivities
Mutational Control
Control
Multi-input Genetic Logic Gates
- Genetic Two-Input AND
- A multi-input signal integrator
- Inverters
Memory Systems
- Invertible Switch Engineering
Signal Pathway Logic
- Signaling Scaffold Engineering
Timers
Instrumentation
- Expressible anoxic fluorophors
- molecular beacons for transcript monitoring
