SynBERC:Tumors: Difference between revisions

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=== Cell Attachment/Invasion ===
=== Cell Attachment/Invasion ===
*Modified pili
*Invasin Engineering
*Invasin Engineering


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=== Synthesis and Delivery of Therapeutics ===
=== Synthesis and Delivery of Therapeutics ===
* Type III Secretion Engineering
* Type III Secretion Engineering
* Endocytic vacuole lysis
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===Multi-input Genetic Logic Gates ===
===Multi-input Genetic Logic Gates ===
* Genetic Two-Input AND
* Genetic Two-Input AND
* A multi-input signal integrator
* Inverters


===Memory Systems===
===Memory Systems===

Latest revision as of 09:53, 7 October 2006

->back to main<- ->back to devices<- back to TKB

Tumor Killing Bacterium Devices

Contacts: J. Christopher Anderson, Adam Paul Arkin, Christopher Voigt

Environmental Sensors

Endogeneous promoters sensitive to the different environments may be discovered by microarray analysis, or RIVET-like analysis of cells grown in the appropriate environments. These will need spec sheets made for them. However, how one makes pluggable, dynamic range tunable, synthetic systems for sensing is still an open question.

Serum

Tissue

Tumor

  • Tumor Antigen Touch Sensor

Intracellular


Actuators

Immune Shielding

  • K-Capsule Engineering

Growth Control

  • Iron Uptake Engineering

Cell Attachment/Invasion

  • Modified pili
  • Invasin Engineering

Cell Motility in the Extra- and Intracellular Environments

Synthesis and Delivery of Therapeutics

  • Type III Secretion Engineering
  • Endocytic vacuole lysis


Safety

Metabolic Auxotrophies

  • DAP Engineering

Programmed Suicide Systems

Chemical Sensitivities

Mutational Control


Control

Multi-input Genetic Logic Gates

  • Genetic Two-Input AND
  • A multi-input signal integrator
  • Inverters

Memory Systems

  • Invertible Switch Engineering

Signal Pathway Logic

  • Signaling Scaffold Engineering

Timers


Instrumentation

  • Expressible anoxic fluorophors
  • molecular beacons for transcript monitoring