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<h3>'''Making life better, one part at a time.''' </h3><br>
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[[Image:Syntheticlogo.png|SYNTHETIC logo]]
Go to [http://syntheticbiology.org/ http://syntheticbiology.org/]
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'''<big>Synthetic Biology</big> is '''<br>
'''A) the design and construction of new biological parts, devices, and systems, and'''<br>
'''B) the re-design of existing, natural biological systems for useful purposes.'''
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<small>([[Biología Sintética|<font color="white">Español</font>]])</small>
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<div>[[Image:Cells-to-gears-big.png|750px|Synthetic Biology Logo]]</div>
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== About Us ==
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This site is sponsored & maintained by members of the MIT Synthetic Biology Working Group.  Please see our [[SB:FAQ|FAQ]] if you've questions about what we do.


Current members are associated with the [[Endy Lab]], the [[Knight Lab]], [http://www.csail.mit.edu/index.php Computer Science and Artificial Intelligence Laboratory], the [http://web.mit.edu/biology Department of Biology], the [http://web.mit.edu/be Biological Engineering Division], and the [http://www.eecs.mit.edu/ Department of Electrical Engineering & Computer Science] at [http://web.mit.edu MIT].
<h3>Community news</h3>
* [http://www.taosciences.it/ssbss2015/ International Synthetic and Systems Biology Summer School], Taormina, Italy, 5 - 9 July 2015
MIT folks can add/remove themselves to the "synthbio" mailing list [https://ca.mit.edu/moira/index.jhtml here].
* [http://synbiobeta.com/event/san-francisco-2014/ SynBioBeta SF 2014], San Francisco, November 13 - 15 2014
* First lab manual for SynBio published [http://www.worldscientific.com/worldscibooks/10.1142/9061#t=aboutBook Synthetic Biology: A Lab Manual]
* SynBioBeta [http://synbiobeta.com/event/synbiobeta-activate-singapore/ Activate! Singapore], Singapore, June 16th 2014
* [http://www.taosciences.it/ssbss2014/ International Synthetic and Systems Biology Summer School], Taormina, Italy, 15 - 19 June 2014
* SynBioBeta [http://www.synbiobeta.com Conference London 2014] April 3rd.
* New [http://synbiobeta.com/courses Courses in Synthetic Biology] announced February 2014.


== Classes/Competitions ==
<small>[[Synthetic Biology:News | Community news archive]]</small>
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*[[iGEM2005:Main Page|iGEM competitions site]] -- [[iGEM2005.MIT:Main Page|2005 iGEM MIT team]]
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*[http://rosalind.csail.mit.edu/r/parts/htdocs/SBC04/index.cgi 2004 Synthetic Biology Competition]
*[http://polkadots.mit.edu/ IAP 2004 class]
*[http://rosalind.csail.mit.edu/projects/index.cgi IAP 2003 and IAP 2004 projects]


== Projects ==
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*[[The BioBricks Foundation]]
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*[http://parts.mit.edu Registry of Standard Biological Parts]
**[[Registry Wish List]]
*[[Synthetic Genomics Study]]
*[[Standard E. coli Strain for BioBricks]]
*[[Barcodes]]
*[[BioBrick Parts for Plasmid Engineering]]
**[[BioBricks construction tutorial]]
*[[SortoStat]]
*[[Library-based Construction]]
*[[Receiver Definition]]
*[[Error Detection & Correction in Replicating Machines]]


== Docs ==
<h3>Discussions</h3>
* [[Synthetic_Biology:Applications | Applications]]
* [[Synthetic Biology:Abstraction hierarchy | Abstraction hierarchy]]
* [[Synthetic Biology:Semantic web ontology | Semantic web ontology]]
* [[Error Detection & Correction in Replicating Machines | Error detection & correction in replicating machines]]<br>
* [[Publishing Group|Publishing]]<br>
* [[Standardization]]<br>
* [[Synthetic Society]]
* [[Synthetic_Biology:ToolsWishlist | Software Tools Wishlist]]


'''See the [https://dspace.mit.edu/handle/1721.1/18185 Synthetic Biology community] on [http://dspace.mit.edu/ MIT's DSpace] for more publications.'''
* [[Synthetic Biology:SB2.0/Biosecurity resolutions | '''SB2.0 proposed biosecurity resolutions''']]


===Papers===
'''If you'd like to contribute, [[OpenWetWare:How to join|join OpenWetWare]]!'''
*[http://www.nature.com/msb/journal/v1/n1/full/msb4100025.html Refactoring bacteriophage T7] by [[Leon Chan]], [[Sriram Kosuri]] and [[Drew Endy]] with commentary [http://www.nature.com/msb/journal/v1/n1/full/msb4100028.html Engineering novel life] by [[Tom Knight]]
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===Theses===
<h3>Resources</h3>
*[http://hdl.handle.net/1721.1/7115 BioJADE: A Design and Simulation Tool for Synthetic Biological Systems] by Jonathan Goler
* [[SynBio books]]
*[http://hdl.handle.net/1721.1/16618 Fluorescence assay for polymerase arrival rates] by [[Austin Che]]
* [[Synthetic Biology:SB101|Synthetic Biology 101]]
* [[Synthetic Biology:DNA synthesis order reviews|Reviews of DNA synthesis companies]]
* [[Synthetic Biology:Press | Press articles]]
* Publications: [[Synthetic_Biology:Articles|citeulike]], [[Synthetic_Biology:Connotea|connotea]],  [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&amp;term=%22synthetic%20biology%22&amp;DB=pubmed PubMed]
* [[Synthetic Biology:Documents | Documents]]
* [[Synthetic Biology:Conferences | Conferences]]
* [http://webcast.berkeley.edu/courses/archive.php?seriesid=1906978261 LBL's Synthetic Biology Lecture Series archive]
* [[Synthetic Biology:Mailing lists | Mailing lists]]
* [[Synthetic Biology:Graduate | Graduate Programs]]
* [[Synthetic Biology:All levels |Positions]]
* [[Synthetic Biology:Industry | Industry]]
* [[Synthetic_Biology:Tools|Online tools]]
* [[Synthetic Biology:Related links | Related links]]


===Technical Reports===
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*Technical Report 0: [http://hdl.handle.net/1721.1/21168 Idempotent Vector Design for Standard Assembly of BioBricks] by [[Tom Knight]]
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*Technical Report 1: [http://hdl.handle.net/1721.1/21167 DARPA BioComp Plasmid Distribution 1.00 of Standard Biobrick Components] by [[Tom Knight]]


===Presentations===
<h3>Initiatives</h3>
*A set of [http://web.mit.edu/endy/www/scraps/talks/ presentation slides] from various talks by [[Drew Endy]], many of which focus on the engineering of biology.
* [[Main Page | OpenWetWare]]
* [[Synthetic Genomics Study]]
* [[Synthetic Biology:BioBricks | BioBricks]] (help wanted!)
* [[The BioBricks Foundation]]
* [http://partsregistry.org Registry of Standard Biological Parts]
* [http://synberc.org SynBERC]
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===Thesis Proposals===
<h3>Projects</h3>
*[http://hdl.handle.net/1721.1/19813 Engineering the Interface Between Cellular Chassis and Integrated Biological Systems] by [[Barry Canton]]
* [[SortoStat|Cell sorter SortoStat]]
*[http://hdl.handle.net/1721.1/21169 Design and Evolution of Engineered Biological Systems] by [[Jason Kelly]]
* [[Synthetic Biology:Collaborative Projects|Collaborative Projects]]
* [[E. coli Automatic Directed Evolution Machine project|''E. coli'' Automatic Directed Evolution Machine (E.ADEM) project]]
* [[Engineering the Host/System Interface]]
* [[Minimal Cell Project (MCP)]]
* [[Rebuilding T7]]
* [[Synthetic E. coli genome project]]
* [[Synthetic Mycoplasma genome project]]
* [[Synthetic yeast genome project]]
* [[Rosetta | Team Synthetic on Rosetta@Home]] (add your cycles)


===Working Drafts===
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*Draft 1: [http://docs.syntheticbiology.org/LacOperator.doc Regulatory Schemes in Biological Networks to Produce Desired Response and Stability.  The genetic inverter: A computational case study]
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*Draft 2: [http://docs.syntheticbiology.org/HomologRecomb.pdf Recombineering: Homologous Recombination-Mediated DNA Engineering in E. coli]
*Draft 3: [http://www.swiss.ai.mit.edu/~gjs/syntheticbiology/models.pdf Electrical Models for Genetic Regulatory Elements]
*Draft 4: Plasmid Engineering [http://docs.syntheticbiology.org/PlasmidEngineering.pdf (pdf)] [http://docs.syntheticbiology.org/PlasmidEngineering.doc (doc)]


== Conferences ==
<h3>iGEM & Outreach</h3>
*[http://conference.syntheticbiology.org/ The First International Meeting on Synthetic Biology]
*iGEM Competition
*Synthetic Biology 2.0 is scheduled for May 20-22, 2006 at UC Berkeley. 
**[http://igem.org/Main_Page iGEM home page]
**Exact schedule and registration details still to be announced.
**[http://partsregistry.org Registry of Standard Biological Parts]
* [http://www.icsb-2005.org/ Sixth International Conference on Systems Biology (ICSB 2005)]
**[http://igem.org/Previous_iGEM_Competitions Prior iGEM competitions]
* [http://www.venterinstitute.org/gsac/programandspeakers.php Venter Institute Conference: Genomes, Medicine, and the Environment]


== News ==
*Information
* A [https://dspace.mit.edu/handle/1721.1/18185 Synthetic Biology community] has been set up on [https://dspace.mit.edu/ MIT's DSpace].
**[[Synthetic Biology:Who we are | About us]]
* MIT, the J. Craig Venter Institute in Rockville, Md., and the Center for Strategic and International Studies in Washington, D.C. announce a new study of the societal implications of synthetic genomics.  Press releases: [http://web.mit.edu/newsoffice/2005/syntheticbio.html MIT], [http://www.csis.org/press/pr05_23.pdf CSIS] and [http://www.venterinstitute.org/press/news/news_2005_06_28.php Venter Institute].
**[[Synthetic Biology:FAQ | FAQ]]
**[[Synthetic Genomics Study]]
 
* [http://www.syntheticgenomics.com Synthetic Genomics, Inc.] has been launched to develop new approaches to biological energy.
*Courses
* Check out [http://taqdot.org/ taqdot: News for the open source and synthetic biology community]
** "Synthetic Biology for Computer Programmers" [http://www.synb.org a one day course]
* [http://codondevices.com/ Codon Devices] is founded to "pioneer the emerging field of synthetic biology."
**[[20.109]] or [[BE.109]] (MIT)
* [[SB:News|Old news links]]
**[[BE.180]] (MIT)
**[[Synbio 2007]] or [[Keasling:_Synthetic_Biology_Class|Implications and Applications of Synthetic Biology]] (UC Berkeley)<br>
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<h3>Contributors</h3>
*[[iGEM|iGEM teams on OpenWetWare]]
*Labs
** [[Church Lab]]
** [[Collins Lab]]
** [[Ellington Lab]]
** [[Endy Lab]]
** [[Forster Lab]]
** [[Keasling Lab]]
** [[Knight Lab]]
** [[Silver Lab]]
** [[Venter Lab]]
*[[Synthetic Biology:People| People]]
 
'''If you'd like to contribute, [[OpenWetWare:How to join|join OpenWetWare]]!'''
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{{Synthetic biology bottom}}

Revision as of 01:46, 20 October 2014

<wikionly> Go to http://syntheticbiology.org/ </wikionly>

Synthetic Biology is
A) the design and construction of new biological parts, devices, and systems, and
B) the re-design of existing, natural biological systems for useful purposes.

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Making life better, one part at a time.