Synthetic Society/SB Reality: Difference between revisions

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==Construction Technology==
==Construction Technology==


''Conclusion:  It is possible to construct any piece of DNA.''<br>
'''Conclusion:  It is possible to construct any piece of DNA.'''<br>
<br>
<br>
Characteristics as of 1 February 2006:
Characteristics as of 1 February 2006:

Revision as of 08:27, 1 February 2006

Construction Technology

Conclusion: It is possible to construct any piece of DNA.

Characteristics as of 1 February 2006:

  • Cost. ~$1 per bp
  • Length. ~100 bp direct chemical synthesis, ~15,000 bp PCR assembly, ~3,500,000 bp inchworm elongation
  • Error Rate. From 1:10 to effectively zero
  • Time. 6 hours for 100 bp, 2-6 weeks for 15,000 bp, ~2 months for 50,000 bp, ~7 years for 3,500,000 bp
  • Diversity. From one molecule to millions of molecules (heavily dependent on method)
  • Terms of Sale. Varied (from no-strings-attached to full-rights-reserved).


Examples:

  • 1918 Flu resurrection
  • Refactoring Bacteriophage T7
  • Poliovirus synthesis
  • PhiX174 synthesis
  • E.coli camera
  • Programmed pattern formation
  • Venter at NSABB
  • Two genomes, one cell
  • Stemmer
  • Baric

Ownership, Sharing, & Innovation Technology

  • MTA examples
  • BioBrick examples