Talk:CH391L/S12/Toggle Switches, Repressilators, and Counters

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*'''[[User:Midhat Patel|Midhat Patel]] 12:58, 3 April 2012 (EDT)''': Are toggle switches used to detect pollution levels? It seems as though they can be used as detectors for the presence of specific molecules that would induce production of some indicator when a threshold level of the pollutant is surpassed.
*'''[[User:Midhat Patel|Midhat Patel]] 12:58, 3 April 2012 (EDT)''': Are toggle switches used to detect pollution levels? It seems as though they can be used as detectors for the presence of specific molecules that would induce production of some indicator when a threshold level of the pollutant is surpassed.
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**'''[[User:Jeffrey E. Barrick|Jeffrey E. Barrick]] 12:25, 6 April 2012 (EDT)''':This sounds familiar. Here's an older paper talking about that application of cells as sensors, but it doesn't mention using toggle switches <cite>Belkin2003</cite>. Maybe a newer review would. Definitely an interesting idea for environmental modeling. It would mean that you don't just get a readout of current levels of a pollutant, but the largest fluctuations that have ever been seen in the history of the cell population.
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== References ==
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<biblio>
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#Belkin2003 pmid=12831895
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//Microbial whole-cell sensing systems of environmental pollutants
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</biblio>

Revision as of 11:25, 6 April 2012

  • Adam Meyer 15:55, 2 April 2012 (EDT):the repressilator in real life. "useless" is analogous to an auto-repressor. "useless2" is analogous to a repressilator. Actually, it is not exactly analogous, as each components turns itself off and the other on (instead of each turning the other off), but the oscillatory behavior is the same.
  • Midhat Patel 12:58, 3 April 2012 (EDT): Are toggle switches used to detect pollution levels? It seems as though they can be used as detectors for the presence of specific molecules that would induce production of some indicator when a threshold level of the pollutant is surpassed.
    • Jeffrey E. Barrick 12:25, 6 April 2012 (EDT):This sounds familiar. Here's an older paper talking about that application of cells as sensors, but it doesn't mention using toggle switches [1]. Maybe a newer review would. Definitely an interesting idea for environmental modeling. It would mean that you don't just get a readout of current levels of a pollutant, but the largest fluctuations that have ever been seen in the history of the cell population.

References

  1. Belkin S. . pmid:12831895. PubMed HubMed [Belkin2003]
    Microbial whole-cell sensing systems of environmental pollutants

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