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		<title>Talk:CH391L/S13/Metagenomics &amp; Bioprospecting - Revision history</title>
		<link>http://www.openwetware.org/index.php?title=Talk:CH391L/S13/Metagenomics_%26_Bioprospecting&amp;action=history</link>
		<description>Revision history for this page on the wiki</description>
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			<title>Jeffrey E. Barrick: /* Metabolic Engineering */</title>
			<link>http://www.openwetware.org/index.php?title=Talk:CH391L/S13/Metagenomics_%26_Bioprospecting&amp;diff=679070&amp;oldid=prev</link>
			<description>&lt;p&gt;&lt;span class=&quot;autocomment&quot;&gt;Metabolic Engineering&lt;/span&gt;&lt;/p&gt;

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				&lt;td colspan='2' style=&quot;background-color: white; color:black;&quot;&gt;←Older revision&lt;/td&gt;
				&lt;td colspan='2' style=&quot;background-color: white; color:black;&quot;&gt;Revision as of 15:30, 25 February 2013&lt;/td&gt;
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		&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 19:&lt;/td&gt;
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&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Alvaro E. Rodriguez M.|Alvaro E. Rodriguez M.]] 19:32, 21 February 2013 (EST)''':Hey Jeff, It could be nice if you invited [http://bk21.ajou.ac.kr/nanomed/english/professor/professor03_09.jsp Dr. Pyung Cheon Lee]&amp;nbsp; to talk, since he does work in metabolic engineering.&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Alvaro E. Rodriguez M.|Alvaro E. Rodriguez M.]] 19:32, 21 February 2013 (EST)''':Hey Jeff, It could be nice if you invited [http://bk21.ajou.ac.kr/nanomed/english/professor/professor03_09.jsp Dr. Pyung Cheon Lee]&amp;nbsp; to talk, since he does work in metabolic engineering.&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;**'''[[User:Kevin Baldridge|Kevin Baldridge]] 10:24, 25 February 2013 (EST)''':Unless I'm missing something he's not exactly local? If you are looking for metabolic engineering work, you might look a little closer to home in [http://www.che.utexas.edu/faculty-staff/faculty-directory/alper/ Dr. Hal Alper's] group&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;**'''[[User:Kevin Baldridge|Kevin Baldridge]] 10:24, 25 February 2013 (EST)''':Unless I'm missing something he's not exactly local? If you are looking for metabolic engineering work, you might look a little closer to home in [http://www.che.utexas.edu/faculty-staff/faculty-directory/alper/ Dr. Hal Alper's] group&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot;&gt;&amp;nbsp;&lt;/td&gt;&lt;td class='diff-marker'&gt;+&lt;/td&gt;&lt;td style=&quot;background: #cfc; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;color: red; font-weight: bold; text-decoration: none;&quot;&gt;***'''[[User:Jeffrey E. Barrick|Jeffrey E. Barrick]] 10:30, 25 February 2013 (EST)''':Dr. Alper talked to class last year, which was great. Alvaro didn't mention that Dr. Lee is visiting my lab for the year. Both do fun things.&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;==Human Microbiome Project (HMP)==&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;==Human Microbiome Project (HMP)==&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Gabriel Wu|Gabriel Wu]] 17:43, 18 February 2013 (EST)''': The first major paper release of the Human Microbiome Project (HMP) has been published. There were two big papers in Nature in June, 2012 [http://www.genome.gov/Pages/Newsroom/CurrentNewsReleases/Nature_HMP_061312.pdf 1], [http://www.genome.gov/Pages/Newsroom/CurrentNewsReleases/Nature_HMP_Framework_061312.pdf 2]. These papers accompanied a coordinated release of about a dozen papers in various PLoS journals [http://www.genome.gov/27549115].&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Gabriel Wu|Gabriel Wu]] 17:43, 18 February 2013 (EST)''': The first major paper release of the Human Microbiome Project (HMP) has been published. There were two big papers in Nature in June, 2012 [http://www.genome.gov/Pages/Newsroom/CurrentNewsReleases/Nature_HMP_061312.pdf 1], [http://www.genome.gov/Pages/Newsroom/CurrentNewsReleases/Nature_HMP_Framework_061312.pdf 2]. These papers accompanied a coordinated release of about a dozen papers in various PLoS journals [http://www.genome.gov/27549115].&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
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			<pubDate>Mon, 25 Feb 2013 15:30:50 GMT</pubDate>			<dc:creator>Jeffrey E. Barrick</dc:creator>			<comments>http://www.openwetware.org/wiki/Talk:CH391L/S13/Metagenomics_%26_Bioprospecting</comments>		</item>
		<item>
			<title>Kevin Baldridge: /* Metabolic Engineering */</title>
			<link>http://www.openwetware.org/index.php?title=Talk:CH391L/S13/Metagenomics_%26_Bioprospecting&amp;diff=679069&amp;oldid=prev</link>
			<description>&lt;p&gt;&lt;span class=&quot;autocomment&quot;&gt;Metabolic Engineering&lt;/span&gt;&lt;/p&gt;

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				&lt;td colspan='2' style=&quot;background-color: white; color:black;&quot;&gt;←Older revision&lt;/td&gt;
				&lt;td colspan='2' style=&quot;background-color: white; color:black;&quot;&gt;Revision as of 15:24, 25 February 2013&lt;/td&gt;
			&lt;/tr&gt;
		&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 18:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 18:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Gabriel Wu|Gabriel Wu]] 18:26, 18 February 2013 (EST)''': A short interesting article about the difference between microbial production (synthetic biology style) versus chemical synthesis. [http://www.nature.com/nature/journal/v492/n7428/full/492188a.html]&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Gabriel Wu|Gabriel Wu]] 18:26, 18 February 2013 (EST)''': A short interesting article about the difference between microbial production (synthetic biology style) versus chemical synthesis. [http://www.nature.com/nature/journal/v492/n7428/full/492188a.html]&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Alvaro E. Rodriguez M.|Alvaro E. Rodriguez M.]] 19:32, 21 February 2013 (EST)''':Hey Jeff, It could be nice if you invited [http://bk21.ajou.ac.kr/nanomed/english/professor/professor03_09.jsp Dr. Pyung Cheon Lee]&amp;nbsp; to talk, since he does work in metabolic engineering.&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Alvaro E. Rodriguez M.|Alvaro E. Rodriguez M.]] 19:32, 21 February 2013 (EST)''':Hey Jeff, It could be nice if you invited [http://bk21.ajou.ac.kr/nanomed/english/professor/professor03_09.jsp Dr. Pyung Cheon Lee]&amp;nbsp; to talk, since he does work in metabolic engineering.&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt;-&lt;/td&gt;&lt;td style=&quot;background: #ffa; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Kevin Baldridge|Kevin Baldridge]] 10:24, 25 February 2013 (EST)''':Unless I'm missing something he's not exactly local? If you are looking for metabolic engineering work, you might look a little closer to home in [http://www.che.utexas.edu/faculty-staff/faculty-directory/alper/ Dr. Hal Alper's] group&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt;+&lt;/td&gt;&lt;td style=&quot;background: #cfc; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;&lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;*&lt;/ins&gt;*'''[[User:Kevin Baldridge|Kevin Baldridge]] 10:24, 25 February 2013 (EST)''':Unless I'm missing something he's not exactly local? If you are looking for metabolic engineering work, you might look a little closer to home in [http://www.che.utexas.edu/faculty-staff/faculty-directory/alper/ Dr. Hal Alper's] group&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;==Human Microbiome Project (HMP)==&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;==Human Microbiome Project (HMP)==&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Gabriel Wu|Gabriel Wu]] 17:43, 18 February 2013 (EST)''': The first major paper release of the Human Microbiome Project (HMP) has been published. There were two big papers in Nature in June, 2012 [http://www.genome.gov/Pages/Newsroom/CurrentNewsReleases/Nature_HMP_061312.pdf 1], [http://www.genome.gov/Pages/Newsroom/CurrentNewsReleases/Nature_HMP_Framework_061312.pdf 2]. These papers accompanied a coordinated release of about a dozen papers in various PLoS journals [http://www.genome.gov/27549115].&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Gabriel Wu|Gabriel Wu]] 17:43, 18 February 2013 (EST)''': The first major paper release of the Human Microbiome Project (HMP) has been published. There were two big papers in Nature in June, 2012 [http://www.genome.gov/Pages/Newsroom/CurrentNewsReleases/Nature_HMP_061312.pdf 1], [http://www.genome.gov/Pages/Newsroom/CurrentNewsReleases/Nature_HMP_Framework_061312.pdf 2]. These papers accompanied a coordinated release of about a dozen papers in various PLoS journals [http://www.genome.gov/27549115].&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
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			<pubDate>Mon, 25 Feb 2013 15:24:30 GMT</pubDate>			<dc:creator>Kevin Baldridge</dc:creator>			<comments>http://www.openwetware.org/wiki/Talk:CH391L/S13/Metagenomics_%26_Bioprospecting</comments>		</item>
		<item>
			<title>Kevin Baldridge: /* Metabolic Engineering */</title>
			<link>http://www.openwetware.org/index.php?title=Talk:CH391L/S13/Metagenomics_%26_Bioprospecting&amp;diff=679068&amp;oldid=prev</link>
			<description>&lt;p&gt;&lt;span class=&quot;autocomment&quot;&gt;Metabolic Engineering&lt;/span&gt;&lt;/p&gt;

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				&lt;td colspan='2' style=&quot;background-color: white; color:black;&quot;&gt;←Older revision&lt;/td&gt;
				&lt;td colspan='2' style=&quot;background-color: white; color:black;&quot;&gt;Revision as of 15:24, 25 February 2013&lt;/td&gt;
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		&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 17:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 17:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;***'''[[User:Thomas Wall|Thomas Wall]] 23:14, 2/21/2013 (EST)''': I have been chomping at the bit to do a synthetic biology project like this for no less than two years&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;***'''[[User:Thomas Wall|Thomas Wall]] 23:14, 2/21/2013 (EST)''': I have been chomping at the bit to do a synthetic biology project like this for no less than two years&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Gabriel Wu|Gabriel Wu]] 18:26, 18 February 2013 (EST)''': A short interesting article about the difference between microbial production (synthetic biology style) versus chemical synthesis. [http://www.nature.com/nature/journal/v492/n7428/full/492188a.html]&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Gabriel Wu|Gabriel Wu]] 18:26, 18 February 2013 (EST)''': A short interesting article about the difference between microbial production (synthetic biology style) versus chemical synthesis. [http://www.nature.com/nature/journal/v492/n7428/full/492188a.html]&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt;-&lt;/td&gt;&lt;td style=&quot;background: #ffa; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Alvaro E. Rodriguez M.|Alvaro E. Rodriguez M.]] 19:32, 21 February 2013 (EST)''':Hey Jeff, It could be nice if you invited [http://bk21.ajou.ac.kr/nanomed/english/professor/professor03_09.jsp Dr. Pyung Cheon Lee]&amp;nbsp; to talk, since he does work in metabolic engineering. &amp;nbsp;&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt;+&lt;/td&gt;&lt;td style=&quot;background: #cfc; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Alvaro E. Rodriguez M.|Alvaro E. Rodriguez M.]] 19:32, 21 February 2013 (EST)''':Hey Jeff, It could be nice if you invited [http://bk21.ajou.ac.kr/nanomed/english/professor/professor03_09.jsp Dr. Pyung Cheon Lee]&amp;nbsp; to talk, since he does work in metabolic engineering.&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot;&gt;&amp;nbsp;&lt;/td&gt;&lt;td class='diff-marker'&gt;+&lt;/td&gt;&lt;td style=&quot;background: #cfc; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;&lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;*'''[[User:Kevin Baldridge|Kevin Baldridge]] 10:24, 25 February 2013 (EST)''':Unless I'm missing something he's not exactly local? If you are looking for metabolic engineering work, you might look a little closer to home in [http://www.che.utexas.edu/faculty-staff/faculty-directory/alper/ Dr. Hal Alper's] group&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;==Human Microbiome Project (HMP)==&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;==Human Microbiome Project (HMP)==&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Gabriel Wu|Gabriel Wu]] 17:43, 18 February 2013 (EST)''': The first major paper release of the Human Microbiome Project (HMP) has been published. There were two big papers in Nature in June, 2012 [http://www.genome.gov/Pages/Newsroom/CurrentNewsReleases/Nature_HMP_061312.pdf 1], [http://www.genome.gov/Pages/Newsroom/CurrentNewsReleases/Nature_HMP_Framework_061312.pdf 2]. These papers accompanied a coordinated release of about a dozen papers in various PLoS journals [http://www.genome.gov/27549115].&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Gabriel Wu|Gabriel Wu]] 17:43, 18 February 2013 (EST)''': The first major paper release of the Human Microbiome Project (HMP) has been published. There were two big papers in Nature in June, 2012 [http://www.genome.gov/Pages/Newsroom/CurrentNewsReleases/Nature_HMP_061312.pdf 1], [http://www.genome.gov/Pages/Newsroom/CurrentNewsReleases/Nature_HMP_Framework_061312.pdf 2]. These papers accompanied a coordinated release of about a dozen papers in various PLoS journals [http://www.genome.gov/27549115].&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
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			<pubDate>Mon, 25 Feb 2013 15:24:17 GMT</pubDate>			<dc:creator>Kevin Baldridge</dc:creator>			<comments>http://www.openwetware.org/wiki/Talk:CH391L/S13/Metagenomics_%26_Bioprospecting</comments>		</item>
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			<title>Andre C Maranhao: Talk:CH391L/S13/Metagenomics &amp; Bioprospecting: Part Deux moved to Talk:CH391L/S13/Metagenomics &amp; Bioprospecting: Cleaning up</title>
			<link>http://www.openwetware.org/index.php?title=Talk:CH391L/S13/Metagenomics_%26_Bioprospecting&amp;diff=678980&amp;oldid=prev</link>
			<description>&lt;p&gt;&lt;a href=&quot;/wiki/Talk:CH391L/S13/Metagenomics_%26_Bioprospecting:_Part_Deux&quot; title=&quot;Talk:CH391L/S13/Metagenomics &amp;amp; Bioprospecting: Part Deux&quot;&gt;Talk:CH391L/S13/Metagenomics &amp;amp; Bioprospecting: Part Deux&lt;/a&gt; moved to &lt;a href=&quot;/wiki/Talk:CH391L/S13/Metagenomics_%26_Bioprospecting&quot; title=&quot;Talk:CH391L/S13/Metagenomics &amp;amp; Bioprospecting&quot;&gt;Talk:CH391L/S13/Metagenomics &amp;amp; Bioprospecting&lt;/a&gt;: Cleaning up&lt;/p&gt;

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				&lt;td colspan='2' style=&quot;background-color: white; color:black;&quot;&gt;Revision as of 04:19, 25 February 2013&lt;/td&gt;
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			<pubDate>Mon, 25 Feb 2013 04:19:11 GMT</pubDate>			<dc:creator>Andre C Maranhao</dc:creator>			<comments>http://www.openwetware.org/wiki/Talk:CH391L/S13/Metagenomics_%26_Bioprospecting</comments>		</item>
		<item>
			<title>Jeffrey E. Barrick at 03:36, 25 February 2013</title>
			<link>http://www.openwetware.org/index.php?title=Talk:CH391L/S13/Metagenomics_%26_Bioprospecting&amp;diff=678959&amp;oldid=prev</link>
			<description>&lt;p&gt;&lt;/p&gt;

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				&lt;td colspan='2' style=&quot;background-color: white; color:black;&quot;&gt;←Older revision&lt;/td&gt;
				&lt;td colspan='2' style=&quot;background-color: white; color:black;&quot;&gt;Revision as of 03:36, 25 February 2013&lt;/td&gt;
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&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Siddharth Das|Siddharth Das]] 21:11, 2/21/2013 (EST)''': You provided an thorough overview of both metagenomics and bioprospecting. Nevertheless, I was wondering if you could expand on the virology section. I don't seem to remember this was a heavily touched upon subject in your presentation and wonder if its needed since it repeats ideas from your intro.&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Siddharth Das|Siddharth Das]] 21:11, 2/21/2013 (EST)''': You provided an thorough overview of both metagenomics and bioprospecting. Nevertheless, I was wondering if you could expand on the virology section. I don't seem to remember this was a heavily touched upon subject in your presentation and wonder if its needed since it repeats ideas from your intro.&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Thomas Wall|Thomas Wall]] 23:07, 2/21/2013 (EST)''': This topic is pretty close to my heart having worked on several projects of this nature, check me out http://aem.asm.org/content/75/9/2735&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Thomas Wall|Thomas Wall]] 23:07, 2/21/2013 (EST)''': This topic is pretty close to my heart having worked on several projects of this nature, check me out http://aem.asm.org/content/75/9/2735&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot;&gt;&amp;nbsp;&lt;/td&gt;&lt;td class='diff-marker'&gt;+&lt;/td&gt;&lt;td style=&quot;background: #cfc; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;color: red; font-weight: bold; text-decoration: none;&quot;&gt;**'''[[User:Jeffrey E. Barrick|Jeffrey E. Barrick]] 22:36, 24 February 2013 (EST)''':Neat paper topic!&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Thomas Wall|Thomas Wall]] 23:25, 2/21/2013 (EST)''': At the SGI christmas party one year they had a video of Craig Venter on his boat with the SNL song &amp;quot;I'm on a boat&amp;quot; playing, it was pretty hilarious, sadly I can't find it online, but I will continue to look.&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Thomas Wall|Thomas Wall]] 23:25, 2/21/2013 (EST)''': At the SGI christmas party one year they had a video of Craig Venter on his boat with the SNL song &amp;quot;I'm on a boat&amp;quot; playing, it was pretty hilarious, sadly I can't find it online, but I will continue to look.&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;**'''[[User:Jeffrey E. Barrick|Jeffrey E. Barrick]] 21:40, 24 February 2013 (EST)''':Seems to have been [http://www.youtube.com/watch?v=ORTyaK3d4eA&amp;amp;feature=player_embedded removed from YouTube].&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;**'''[[User:Jeffrey E. Barrick|Jeffrey E. Barrick]] 21:40, 24 February 2013 (EST)''':Seems to have been [http://www.youtube.com/watch?v=ORTyaK3d4eA&amp;amp;feature=player_embedded removed from YouTube].&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
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			<pubDate>Mon, 25 Feb 2013 03:36:16 GMT</pubDate>			<dc:creator>Jeffrey E. Barrick</dc:creator>			<comments>http://www.openwetware.org/wiki/Talk:CH391L/S13/Metagenomics_%26_Bioprospecting</comments>		</item>
		<item>
			<title>Jeffrey E. Barrick at 02:40, 25 February 2013</title>
			<link>http://www.openwetware.org/index.php?title=Talk:CH391L/S13/Metagenomics_%26_Bioprospecting&amp;diff=678955&amp;oldid=prev</link>
			<description>&lt;p&gt;&lt;/p&gt;

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				&lt;td colspan='2' style=&quot;background-color: white; color:black;&quot;&gt;←Older revision&lt;/td&gt;
				&lt;td colspan='2' style=&quot;background-color: white; color:black;&quot;&gt;Revision as of 02:40, 25 February 2013&lt;/td&gt;
			&lt;/tr&gt;
		&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 8:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 8:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Thomas Wall|Thomas Wall]] 23:07, 2/21/2013 (EST)''': This topic is pretty close to my heart having worked on several projects of this nature, check me out http://aem.asm.org/content/75/9/2735&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Thomas Wall|Thomas Wall]] 23:07, 2/21/2013 (EST)''': This topic is pretty close to my heart having worked on several projects of this nature, check me out http://aem.asm.org/content/75/9/2735&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Thomas Wall|Thomas Wall]] 23:25, 2/21/2013 (EST)''': At the SGI christmas party one year they had a video of Craig Venter on his boat with the SNL song &amp;quot;I'm on a boat&amp;quot; playing, it was pretty hilarious, sadly I can't find it online, but I will continue to look.&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Thomas Wall|Thomas Wall]] 23:25, 2/21/2013 (EST)''': At the SGI christmas party one year they had a video of Craig Venter on his boat with the SNL song &amp;quot;I'm on a boat&amp;quot; playing, it was pretty hilarious, sadly I can't find it online, but I will continue to look.&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot;&gt;&amp;nbsp;&lt;/td&gt;&lt;td class='diff-marker'&gt;+&lt;/td&gt;&lt;td style=&quot;background: #cfc; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;color: red; font-weight: bold; text-decoration: none;&quot;&gt;**'''[[User:Jeffrey E. Barrick|Jeffrey E. Barrick]] 21:40, 24 February 2013 (EST)''':Seems to have been [http://www.youtube.com/watch?v=ORTyaK3d4eA&amp;amp;feature=player_embedded removed from YouTube].&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot;&gt;&amp;nbsp;&lt;/td&gt;&lt;td class='diff-marker'&gt;+&lt;/td&gt;&lt;td style=&quot;background: #cfc; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;color: red; font-weight: bold; text-decoration: none;&quot;&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;==Metabolic Engineering==&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;==Metabolic Engineering==&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Gabriel Wu|Gabriel Wu]] 18:22, 18 February 2013 (EST)''': The story of taxol is interesting and important. Unfortunately, it hasn't been as successful at commercialization--at least not yet.&amp;nbsp; Another rather impressive story that so far has been more successful commercially is the microbial production of the antimalarial artemisinin.&amp;nbsp; By expressing plant genes in yeast, researchers are able to economically produce large amounts artemisinin precursor. The most recent publication in this field is [http://www.pnas.org/content/109/3/E111.short here].&amp;nbsp; An older, but clearer explanation is [http://www.nature.com/nbt/journal/v21/n7/full/nbt833.html here].&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Gabriel Wu|Gabriel Wu]] 18:22, 18 February 2013 (EST)''': The story of taxol is interesting and important. Unfortunately, it hasn't been as successful at commercialization--at least not yet.&amp;nbsp; Another rather impressive story that so far has been more successful commercially is the microbial production of the antimalarial artemisinin.&amp;nbsp; By expressing plant genes in yeast, researchers are able to economically produce large amounts artemisinin precursor. The most recent publication in this field is [http://www.pnas.org/content/109/3/E111.short here].&amp;nbsp; An older, but clearer explanation is [http://www.nature.com/nbt/journal/v21/n7/full/nbt833.html here].&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
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			<pubDate>Mon, 25 Feb 2013 02:40:47 GMT</pubDate>			<dc:creator>Jeffrey E. Barrick</dc:creator>			<comments>http://www.openwetware.org/wiki/Talk:CH391L/S13/Metagenomics_%26_Bioprospecting</comments>		</item>
		<item>
			<title>Thomas Wall at 04:37, 22 February 2013</title>
			<link>http://www.openwetware.org/index.php?title=Talk:CH391L/S13/Metagenomics_%26_Bioprospecting&amp;diff=678475&amp;oldid=prev</link>
			<description>&lt;p&gt;&lt;/p&gt;

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				&lt;td colspan='2' style=&quot;background-color: white; color:black;&quot;&gt;←Older revision&lt;/td&gt;
				&lt;td colspan='2' style=&quot;background-color: white; color:black;&quot;&gt;Revision as of 04:37, 22 February 2013&lt;/td&gt;
			&lt;/tr&gt;
		&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 7:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 7:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Siddharth Das|Siddharth Das]] 21:11, 2/21/2013 (EST)''': You provided an thorough overview of both metagenomics and bioprospecting. Nevertheless, I was wondering if you could expand on the virology section. I don't seem to remember this was a heavily touched upon subject in your presentation and wonder if its needed since it repeats ideas from your intro.&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Siddharth Das|Siddharth Das]] 21:11, 2/21/2013 (EST)''': You provided an thorough overview of both metagenomics and bioprospecting. Nevertheless, I was wondering if you could expand on the virology section. I don't seem to remember this was a heavily touched upon subject in your presentation and wonder if its needed since it repeats ideas from your intro.&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Thomas Wall|Thomas Wall]] 23:07, 2/21/2013 (EST)''': This topic is pretty close to my heart having worked on several projects of this nature, check me out http://aem.asm.org/content/75/9/2735&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Thomas Wall|Thomas Wall]] 23:07, 2/21/2013 (EST)''': This topic is pretty close to my heart having worked on several projects of this nature, check me out http://aem.asm.org/content/75/9/2735&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot;&gt;&amp;nbsp;&lt;/td&gt;&lt;td class='diff-marker'&gt;+&lt;/td&gt;&lt;td style=&quot;background: #cfc; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;color: red; font-weight: bold; text-decoration: none;&quot;&gt;*'''[[User:Thomas Wall|Thomas Wall]] 23:25, 2/21/2013 (EST)''': At the SGI christmas party one year they had a video of Craig Venter on his boat with the SNL song &amp;quot;I'm on a boat&amp;quot; playing, it was pretty hilarious, sadly I can't find it online, but I will continue to look.&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;==Metabolic Engineering==&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;==Metabolic Engineering==&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Gabriel Wu|Gabriel Wu]] 18:22, 18 February 2013 (EST)''': The story of taxol is interesting and important. Unfortunately, it hasn't been as successful at commercialization--at least not yet.&amp;nbsp; Another rather impressive story that so far has been more successful commercially is the microbial production of the antimalarial artemisinin.&amp;nbsp; By expressing plant genes in yeast, researchers are able to economically produce large amounts artemisinin precursor. The most recent publication in this field is [http://www.pnas.org/content/109/3/E111.short here].&amp;nbsp; An older, but clearer explanation is [http://www.nature.com/nbt/journal/v21/n7/full/nbt833.html here].&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Gabriel Wu|Gabriel Wu]] 18:22, 18 February 2013 (EST)''': The story of taxol is interesting and important. Unfortunately, it hasn't been as successful at commercialization--at least not yet.&amp;nbsp; Another rather impressive story that so far has been more successful commercially is the microbial production of the antimalarial artemisinin.&amp;nbsp; By expressing plant genes in yeast, researchers are able to economically produce large amounts artemisinin precursor. The most recent publication in this field is [http://www.pnas.org/content/109/3/E111.short here].&amp;nbsp; An older, but clearer explanation is [http://www.nature.com/nbt/journal/v21/n7/full/nbt833.html here].&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
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			<pubDate>Fri, 22 Feb 2013 04:37:58 GMT</pubDate>			<dc:creator>Thomas Wall</dc:creator>			<comments>http://www.openwetware.org/wiki/Talk:CH391L/S13/Metagenomics_%26_Bioprospecting</comments>		</item>
		<item>
			<title>Thomas Wall at 04:15, 22 February 2013</title>
			<link>http://www.openwetware.org/index.php?title=Talk:CH391L/S13/Metagenomics_%26_Bioprospecting&amp;diff=678469&amp;oldid=prev</link>
			<description>&lt;p&gt;&lt;/p&gt;

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				&lt;td colspan='2' style=&quot;background-color: white; color:black;&quot;&gt;←Older revision&lt;/td&gt;
				&lt;td colspan='2' style=&quot;background-color: white; color:black;&quot;&gt;Revision as of 04:15, 22 February 2013&lt;/td&gt;
			&lt;/tr&gt;
		&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 11:&lt;/td&gt;
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&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;**'''[[User:Jeffrey E. Barrick|Jeffrey E. Barrick]] 12:58, 20 February 2013 (EST)''':It would be interesting to go back and trace the discovery of those genes.&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;**'''[[User:Jeffrey E. Barrick|Jeffrey E. Barrick]] 12:58, 20 February 2013 (EST)''':It would be interesting to go back and trace the discovery of those genes.&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;**'''[[User:Benjamin Gilman|Benjamin Gilman]] 17:39, 21 February 2013 (EST)''': My understanding is that taxol is currently made by growing ''taxus''(yew tree family) cells in suspension along with the fungus that completes the synthesis, not unlike what happens in actual tree bark.&amp;nbsp; Does anyone know if a similar strategy has ever been used with engineered organisms to synthesize a product in cases where a single species couldn't be coaxed into completing the synthesis?&amp;nbsp; &amp;nbsp;&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;**'''[[User:Benjamin Gilman|Benjamin Gilman]] 17:39, 21 February 2013 (EST)''': My understanding is that taxol is currently made by growing ''taxus''(yew tree family) cells in suspension along with the fungus that completes the synthesis, not unlike what happens in actual tree bark.&amp;nbsp; Does anyone know if a similar strategy has ever been used with engineered organisms to synthesize a product in cases where a single species couldn't be coaxed into completing the synthesis?&amp;nbsp; &amp;nbsp;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt;-&lt;/td&gt;&lt;td style=&quot;background: #ffa; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;**'''[[User:Thomas Wall|Thomas Wall]] 23:&lt;del class=&quot;diffchange diffchange-inline&quot;&gt;07&lt;/del&gt;, 2/21/2013 (EST)''': I have been chomping at the bit to do a synthetic biology project like this for no less than two years&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt;+&lt;/td&gt;&lt;td style=&quot;background: #cfc; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;&lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;*&lt;/ins&gt;**'''[[User:Thomas Wall|Thomas Wall]] 23:&lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;14&lt;/ins&gt;, 2/21/2013 (EST)''': I have been chomping at the bit to do a synthetic biology project like this for no less than two years&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Gabriel Wu|Gabriel Wu]] 18:26, 18 February 2013 (EST)''': A short interesting article about the difference between microbial production (synthetic biology style) versus chemical synthesis. [http://www.nature.com/nature/journal/v492/n7428/full/492188a.html]&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Gabriel Wu|Gabriel Wu]] 18:26, 18 February 2013 (EST)''': A short interesting article about the difference between microbial production (synthetic biology style) versus chemical synthesis. [http://www.nature.com/nature/journal/v492/n7428/full/492188a.html]&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Alvaro E. Rodriguez M.|Alvaro E. Rodriguez M.]] 19:32, 21 February 2013 (EST)''':Hey Jeff, It could be nice if you invited [http://bk21.ajou.ac.kr/nanomed/english/professor/professor03_09.jsp Dr. Pyung Cheon Lee]&amp;nbsp; to talk, since he does work in metabolic engineering. &amp;nbsp;&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Alvaro E. Rodriguez M.|Alvaro E. Rodriguez M.]] 19:32, 21 February 2013 (EST)''':Hey Jeff, It could be nice if you invited [http://bk21.ajou.ac.kr/nanomed/english/professor/professor03_09.jsp Dr. Pyung Cheon Lee]&amp;nbsp; to talk, since he does work in metabolic engineering. &amp;nbsp;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
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			<pubDate>Fri, 22 Feb 2013 04:15:54 GMT</pubDate>			<dc:creator>Thomas Wall</dc:creator>			<comments>http://www.openwetware.org/wiki/Talk:CH391L/S13/Metagenomics_%26_Bioprospecting</comments>		</item>
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			<title>Thomas Wall at 04:15, 22 February 2013</title>
			<link>http://www.openwetware.org/index.php?title=Talk:CH391L/S13/Metagenomics_%26_Bioprospecting&amp;diff=678468&amp;oldid=prev</link>
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				&lt;td colspan='2' style=&quot;background-color: white; color:black;&quot;&gt;Revision as of 04:15, 22 February 2013&lt;/td&gt;
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&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;**'''[[User:Jeffrey E. Barrick|Jeffrey E. Barrick]] 12:58, 20 February 2013 (EST)''':It would be interesting to go back and trace the discovery of those genes.&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;**'''[[User:Jeffrey E. Barrick|Jeffrey E. Barrick]] 12:58, 20 February 2013 (EST)''':It would be interesting to go back and trace the discovery of those genes.&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;**'''[[User:Benjamin Gilman|Benjamin Gilman]] 17:39, 21 February 2013 (EST)''': My understanding is that taxol is currently made by growing ''taxus''(yew tree family) cells in suspension along with the fungus that completes the synthesis, not unlike what happens in actual tree bark.&amp;nbsp; Does anyone know if a similar strategy has ever been used with engineered organisms to synthesize a product in cases where a single species couldn't be coaxed into completing the synthesis?&amp;nbsp; &amp;nbsp;&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;**'''[[User:Benjamin Gilman|Benjamin Gilman]] 17:39, 21 February 2013 (EST)''': My understanding is that taxol is currently made by growing ''taxus''(yew tree family) cells in suspension along with the fungus that completes the synthesis, not unlike what happens in actual tree bark.&amp;nbsp; Does anyone know if a similar strategy has ever been used with engineered organisms to synthesize a product in cases where a single species couldn't be coaxed into completing the synthesis?&amp;nbsp; &amp;nbsp;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot;&gt;&amp;nbsp;&lt;/td&gt;&lt;td class='diff-marker'&gt;+&lt;/td&gt;&lt;td style=&quot;background: #cfc; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;color: red; font-weight: bold; text-decoration: none;&quot;&gt;**'''[[User:Thomas Wall|Thomas Wall]] 23:07, 2/21/2013 (EST)''': I have been chomping at the bit to do a synthetic biology project like this for no less than two years&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Gabriel Wu|Gabriel Wu]] 18:26, 18 February 2013 (EST)''': A short interesting article about the difference between microbial production (synthetic biology style) versus chemical synthesis. [http://www.nature.com/nature/journal/v492/n7428/full/492188a.html]&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Gabriel Wu|Gabriel Wu]] 18:26, 18 February 2013 (EST)''': A short interesting article about the difference between microbial production (synthetic biology style) versus chemical synthesis. [http://www.nature.com/nature/journal/v492/n7428/full/492188a.html]&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Alvaro E. Rodriguez M.|Alvaro E. Rodriguez M.]] 19:32, 21 February 2013 (EST)''':Hey Jeff, It could be nice if you invited [http://bk21.ajou.ac.kr/nanomed/english/professor/professor03_09.jsp Dr. Pyung Cheon Lee]&amp;nbsp; to talk, since he does work in metabolic engineering. &amp;nbsp;&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Alvaro E. Rodriguez M.|Alvaro E. Rodriguez M.]] 19:32, 21 February 2013 (EST)''':Hey Jeff, It could be nice if you invited [http://bk21.ajou.ac.kr/nanomed/english/professor/professor03_09.jsp Dr. Pyung Cheon Lee]&amp;nbsp; to talk, since he does work in metabolic engineering. &amp;nbsp;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
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			<pubDate>Fri, 22 Feb 2013 04:15:33 GMT</pubDate>			<dc:creator>Thomas Wall</dc:creator>			<comments>http://www.openwetware.org/wiki/Talk:CH391L/S13/Metagenomics_%26_Bioprospecting</comments>		</item>
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			<title>Thomas Wall at 04:13, 22 February 2013</title>
			<link>http://www.openwetware.org/index.php?title=Talk:CH391L/S13/Metagenomics_%26_Bioprospecting&amp;diff=678465&amp;oldid=prev</link>
			<description>&lt;p&gt;&lt;/p&gt;

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				&lt;td colspan='2' style=&quot;background-color: white; color:black;&quot;&gt;Revision as of 04:13, 22 February 2013&lt;/td&gt;
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&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Siddharth Das|Siddharth Das]] 21:11, 2/21/2013 (EST)''': You provided an thorough overview of both metagenomics and bioprospecting. Nevertheless, I was wondering if you could expand on the virology section. I don't seem to remember this was a heavily touched upon subject in your presentation and wonder if its needed since it repeats ideas from your intro.&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Siddharth Das|Siddharth Das]] 21:11, 2/21/2013 (EST)''': You provided an thorough overview of both metagenomics and bioprospecting. Nevertheless, I was wondering if you could expand on the virology section. I don't seem to remember this was a heavily touched upon subject in your presentation and wonder if its needed since it repeats ideas from your intro.&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt;-&lt;/td&gt;&lt;td style=&quot;background: #ffa; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;&amp;#160;&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt;+&lt;/td&gt;&lt;td style=&quot;background: #cfc; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;&lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;*'''[[User:Thomas Wall|Thomas Wall]] 23:07, 2/21/2013 (EST)''': This topic is pretty close to my heart having worked on several projects of this nature, check me out http://aem.asm.org/content/75/9/2735&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;==Metabolic Engineering==&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;==Metabolic Engineering==&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Gabriel Wu|Gabriel Wu]] 18:22, 18 February 2013 (EST)''': The story of taxol is interesting and important. Unfortunately, it hasn't been as successful at commercialization--at least not yet.&amp;nbsp; Another rather impressive story that so far has been more successful commercially is the microbial production of the antimalarial artemisinin.&amp;nbsp; By expressing plant genes in yeast, researchers are able to economically produce large amounts artemisinin precursor. The most recent publication in this field is [http://www.pnas.org/content/109/3/E111.short here].&amp;nbsp; An older, but clearer explanation is [http://www.nature.com/nbt/journal/v21/n7/full/nbt833.html here].&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;*'''[[User:Gabriel Wu|Gabriel Wu]] 18:22, 18 February 2013 (EST)''': The story of taxol is interesting and important. Unfortunately, it hasn't been as successful at commercialization--at least not yet.&amp;nbsp; Another rather impressive story that so far has been more successful commercially is the microbial production of the antimalarial artemisinin.&amp;nbsp; By expressing plant genes in yeast, researchers are able to economically produce large amounts artemisinin precursor. The most recent publication in this field is [http://www.pnas.org/content/109/3/E111.short here].&amp;nbsp; An older, but clearer explanation is [http://www.nature.com/nbt/journal/v21/n7/full/nbt833.html here].&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
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			<pubDate>Fri, 22 Feb 2013 04:13:06 GMT</pubDate>			<dc:creator>Thomas Wall</dc:creator>			<comments>http://www.openwetware.org/wiki/Talk:CH391L/S13/Metagenomics_%26_Bioprospecting</comments>		</item>
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