Talk:CH391L/S13/Probiotics

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*'''[[User:Kevin Baldridge|Kevin Baldridge]] 17:27, 18 March 2013 (EDT)''':I'm pretty sure it's SV40 not VS40 for the broad host range plasmid
*'''[[User:Kevin Baldridge|Kevin Baldridge]] 17:27, 18 March 2013 (EDT)''':I'm pretty sure it's SV40 not VS40 for the broad host range plasmid
*'''[[User:Gabriel Wu|Gabriel Wu]] 17:32, 18 March 2013 (EDT)''': Some good references showing fecal transplantation can cure recurrent C. difficile infections. [http://www.nejm.org/doi/full/10.1056/NEJMoa1205037 humans], [http://www.plospathogens.org/article/info%3Adoi%2F10.1371%2Fjournal.ppat.1002995 mice]
*'''[[User:Gabriel Wu|Gabriel Wu]] 17:32, 18 March 2013 (EDT)''': Some good references showing fecal transplantation can cure recurrent C. difficile infections. [http://www.nejm.org/doi/full/10.1056/NEJMoa1205037 humans], [http://www.plospathogens.org/article/info%3Adoi%2F10.1371%2Fjournal.ppat.1002995 mice]
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**'''[[User:Benjamin Gilman|Benjamin Gilman]] 19:21, 21 March 2013 (EDT)''': The explanation of how this works in the context of patient treatment isn't clear on the page.  The problem is that extended treatment with broad-spectrum antibiotics kills off many of the bacteria in a patient's digestive tract, allowing C. difficile to take hold.  A fecal transplant introduces thousands(?) of species of bacteria to combat that.
*'''[[User:Gabriel Wu|Gabriel Wu]] 17:40, 18 March 2013 (EDT)''': An ambitious synthetic biology application of designing a tumor killing (or destroying) bacteria. [http://www.ncbi.nlm.nih.gov/pubmed/16330045]
*'''[[User:Gabriel Wu|Gabriel Wu]] 17:40, 18 March 2013 (EDT)''': An ambitious synthetic biology application of designing a tumor killing (or destroying) bacteria. [http://www.ncbi.nlm.nih.gov/pubmed/16330045]
*'''[[User:Gabriel Wu|Gabriel Wu]] 17:42, 18 March 2013 (EDT)''': You have to mention yogurt (and possibly cheese, bread, beer) have micro-organisms that have human benefits.
*'''[[User:Gabriel Wu|Gabriel Wu]] 17:42, 18 March 2013 (EDT)''': You have to mention yogurt (and possibly cheese, bread, beer) have micro-organisms that have human benefits.
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**'''[[User:Benjamin Gilman|Benjamin Gilman]] 19:21, 21 March 2013 (EDT)''': Because there aren't many examples of genetically engineered microorganisms being used as probiotics, you might want to talk about some of the examples where more traditional techniques were used to alter cells used in these products.  Ale yeast, for example, has been evolved to generate more esters and flocculate among other things, but that also effects the nutritional value of beer.  You might also find out how Dannon found/developed the bacteria strain they use in the activia yogurt.

Revision as of 19:21, 21 March 2013

  • Benjamin Gilman 17:13, 18 March 2013 (EDT): 'The advent of probiotics' section is duplicated on the page. I'd get rid of the copy in your introduction.
  • Benjamin Gilman 17:25, 18 March 2013 (EDT): As we said in class, you should explain and cite the mention of bacterial strains that cause tumors to shrink.
  • Kevin Baldridge 17:27, 18 March 2013 (EDT):I'm pretty sure it's SV40 not VS40 for the broad host range plasmid
  • Gabriel Wu 17:32, 18 March 2013 (EDT): Some good references showing fecal transplantation can cure recurrent C. difficile infections. humans, mice
    • Benjamin Gilman 19:21, 21 March 2013 (EDT): The explanation of how this works in the context of patient treatment isn't clear on the page. The problem is that extended treatment with broad-spectrum antibiotics kills off many of the bacteria in a patient's digestive tract, allowing C. difficile to take hold. A fecal transplant introduces thousands(?) of species of bacteria to combat that.
  • Gabriel Wu 17:40, 18 March 2013 (EDT): An ambitious synthetic biology application of designing a tumor killing (or destroying) bacteria. [1]
  • Gabriel Wu 17:42, 18 March 2013 (EDT): You have to mention yogurt (and possibly cheese, bread, beer) have micro-organisms that have human benefits.
    • Benjamin Gilman 19:21, 21 March 2013 (EDT): Because there aren't many examples of genetically engineered microorganisms being used as probiotics, you might want to talk about some of the examples where more traditional techniques were used to alter cells used in these products. Ale yeast, for example, has been evolved to generate more esters and flocculate among other things, but that also effects the nutritional value of beer. You might also find out how Dannon found/developed the bacteria strain they use in the activia yogurt.
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