Talk:Harvard:Biophysics 101/2007/Project: Difference between revisions

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==Beyond OMIM==
==Beyond OMIM==
I realize that our project is pretty much entirely designed to interface with OMIM and interact with this database, and I think that's a good place to start.  Not all of our data-samples will be inherited in a Mendelian manner, thus setting a limit to OMIM's power.  This is a concern represented by all of our unassigned tasks.  We've discussed the significance of a 'metabolome' and, accordingly, environmental factors on the emergence of specific phenotypes.  As we resolve the unassigned tasks, we should facilitate this concern in searching for existing reference databases, creating a new one, or creating a parallel search process given a different input.  --[[User:ChristopherNabel|CSN]] 19:35, 20 March 2007 (EST)
I realize that our project is pretty much entirely designed to interface with OMIM and interact with this database, and I think that's a good place to start.  Not all of our data-samples will be inherited in a Mendelian manner, thus setting a limit to OMIM's power.  This is a concern represented by all of our unassigned tasks.  We've discussed the significance of a 'metabolome' and, accordingly, environmental factors on the emergence of specific phenotypes.  As we resolve the unassigned tasks, we should facilitate this concern in searching for existing reference databases, creating a new one, or creating a parallel search process given a different input.  --[[User:ChristopherNabel|CSN]] 19:35, 20 March 2007 (EST)
==Project Ideas==
Are we supposed to alter these outlines as we would envision our final project shaping up?
::Yes.  --[[User:ShawnDouglas|smd]] 01:51, 25 February 2007 (EST)
In class on Tuesday, we talked extensively about personal genomes and data that are available to us now.  In class last Thursday, it appeared that should consider how anticipate the new wave of personal genomes that will come as the technology becomes cheaper.  Does anyone have ideas about how we can interface our two data sources?  I personally think we should write a script to anticipate the future wave of data, but can also tolerate what we have now.  That is, we should optimize our program for future datasets, rather than trying to squeeze more than is feasible from HapMap or HGP.  That's not to say we shouldn't analyze these data, but we do need to prioritize...  [[User:ChristopherNabel|CSN]] 01:41, 28 February 2007 (EST)

Revision as of 23:50, 20 March 2007

BLAST SNP to OMIM

I'm going to take a look at NCBIWWW.py and see if it's modifiable to give us what we want from BLAST SNP. I'm not sure, because it seems that they're working with an HTML output, rather than XML. Can someone please advise? --TChan 13:00, 20 March 2007 (EST)

Beyond OMIM

I realize that our project is pretty much entirely designed to interface with OMIM and interact with this database, and I think that's a good place to start. Not all of our data-samples will be inherited in a Mendelian manner, thus setting a limit to OMIM's power. This is a concern represented by all of our unassigned tasks. We've discussed the significance of a 'metabolome' and, accordingly, environmental factors on the emergence of specific phenotypes. As we resolve the unassigned tasks, we should facilitate this concern in searching for existing reference databases, creating a new one, or creating a parallel search process given a different input. --CSN 19:35, 20 March 2007 (EST)

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