Talk:Todd:Catalytic, Asymmetric Pictet-Spengler Reaction
Use this page for discussion. Preface questions/comments with initials.
MHT - Jan19 - the page is quite long. We could consider splitting into sections if anyone is having a browser problem, but otherwise we keep as-is. Much more convenient having everything on one page.
Things that need doing (updated 20/01/12):
Archived/inactive discussions:
1. KAB attempt to understand 2000 Koomen OrgLett (archived since this paper no longer included)
The figure for Table 1 gives diasteromeric ratios. Where are the diastereomers? I only the possibility for enantiomers in the product. Where's the other stereogenic centre?
They also mentioned "hydrolysis of the starting material" numerous times. I'm assuming they mean hydrolysis of the N-S bond (there doesn't seem any other reasonable place for hydrolysis of the SM to occur), but I just wanted to check.