Template:SBB10 Tn5: Difference between revisions

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==This part is associated with Tn5 transposon devices==
==This part is associated with Tn5 transposon devices==
Tn5 transposase is a popular enzyme that generates protein-DNA complexes called transposomes from DNAs flanked by "terminal repeats".  These terminal repeats, or TR's, are specific ''cis'' elements.  The transposomes are highly reactive and insert the DNA contained within them randomly into other DNAs (such as a genome).  Unlike Sleeping Beauty and piggyBac which comes from eukaryotic organisms, Tn5 comes from enterobacterial tranposons.


References: PMID 18805998, PMID 16079303
'''You should read the following papers'''<br>
References: PMID 12189420, PMID 16079303, PMID 18805998
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Latest revision as of 23:10, 2 February 2010

This part is associated with Tn5 transposon devices

Tn5 transposase is a popular enzyme that generates protein-DNA complexes called transposomes from DNAs flanked by "terminal repeats". These terminal repeats, or TR's, are specific cis elements. The transposomes are highly reactive and insert the DNA contained within them randomly into other DNAs (such as a genome). Unlike Sleeping Beauty and piggyBac which comes from eukaryotic organisms, Tn5 comes from enterobacterial tranposons.

You should read the following papers
References: PMID 12189420, PMID 16079303, PMID 18805998