Template:SBB10 phiC31: Difference between revisions

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==This part is associated with phiC31 integration devices==
==This part is associated with phiC31 integration devices==
phiC31 is a bacteriophage integrase.  It is somewhat similar in mechanism to Cre recombinase, but it acts on the asymmetric sites attB and attP.  It causes these sequences to be recombined to generate attL and attR sequences.  This system is useful for integrating large DNAs site-specifically into genomes.


- Note to Chris: I put up all of the PMID's although I'm not sure they are all relevant. I'm going to go back and remove the unnecessary ones later.
'''You should read the following papers'''<br>
 
References: PMID 14996222, PMID 19002165, PMID 19439387, PMID 12034816
References: PMID 14996222, PMID 19002165, PMID 19439387
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Latest revision as of 23:50, 3 February 2010

This part is associated with phiC31 integration devices

phiC31 is a bacteriophage integrase. It is somewhat similar in mechanism to Cre recombinase, but it acts on the asymmetric sites attB and attP. It causes these sequences to be recombined to generate attL and attR sequences. This system is useful for integrating large DNAs site-specifically into genomes.

You should read the following papers
References: PMID 14996222, PMID 19002165, PMID 19439387, PMID 12034816