Todd:Construction

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(link to page describing synthesis of arylpyrrole analogs)
(Open science papers being written by us and the people we work with)
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[[Todd:Pictet-Spengler to PZQ | Pictet-Spengler route to PZQ]] - Summary of the Lablog [http://www.ourexperiment.org/racemic_pzq Pictet-Spengler route to Praziquantel]<br>
[[Todd:Pictet-Spengler to PZQ | Pictet-Spengler route to PZQ]] - Summary of the Lablog [http://www.ourexperiment.org/racemic_pzq Pictet-Spengler route to Praziquantel]<br>
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[[Todd:Catalytic, Asymmetric Pictet-Spengler Reaction | Catalytic, Asymmetric Pictet-Spengler Reaction]] - A review of the area.<br>
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[[Todd:Asymmetric Hydrogenation of PZQ Enamide | Asymmetric Hydrogenation of PZQ Enamide]] - New paper describing results on the synthetic approach to (''R'')-PZQ based on an asymmetric hydrogenation of a precursor enamide.<br>
[[Todd:Asymmetric Hydrogenation of PZQ Enamide | Asymmetric Hydrogenation of PZQ Enamide]] - New paper describing results on the synthetic approach to (''R'')-PZQ based on an asymmetric hydrogenation of a precursor enamide.<br>
Papers here are being assembled in the open. Those who make/have made substantial contributions to the projects will be named on the papers, which will be submitted for publication as soon as they're finished. Rules for how this should operate will be posted below but will be adapted from those already established for the [http://polymathprojects.org/general-polymath-rules/ Polymath Project]
Papers here are being assembled in the open. Those who make/have made substantial contributions to the projects will be named on the papers, which will be submitted for publication as soon as they're finished. Rules for how this should operate will be posted below but will be adapted from those already established for the [http://polymathprojects.org/general-polymath-rules/ Polymath Project]

Revision as of 06:56, 11 December 2011

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Open science papers being written by us and the people we work with

Synthesis of Analogs of Arylpyrrole Antimalarial Drug Leads This is an undergraduate report describing the synthesis towards analogs of the arylpyrroles, TCMDC 123812 and TCMDC 123794. Raw data in Lablog here

Resolution of Praziquantel - this page is no longer being actively edited since it has been published.
Student-led Optimization of the Resolution of Praziquantel This paper is being written by students participating in the open project whose raw data are here.

Pictet-Spengler route to PZQ - Summary of the Lablog Pictet-Spengler route to Praziquantel

Catalytic, Asymmetric Pictet-Spengler Reaction - A review of the area.

Asymmetric Hydrogenation of PZQ Enamide - New paper describing results on the synthetic approach to (R)-PZQ based on an asymmetric hydrogenation of a precursor enamide.

Papers here are being assembled in the open. Those who make/have made substantial contributions to the projects will be named on the papers, which will be submitted for publication as soon as they're finished. Rules for how this should operate will be posted below but will be adapted from those already established for the Polymath Project

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