Topp:Talks

Protein Stability and Formulation Lab

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Recent presentations

1. High resolution characterization of proteins in amorphous solid powders, E.M. Topp, L.K. Iyer, S.M. Balakrishnan and B. Xie, International Symposium on Polymer Analysis and Characterization, New Orleans, LA, June 9-12, 2013.
2. Challenges and opportunities in pharmacy. University of Wisconsin-Madison, School of Pharmacy, Madison, WI, April 8, 2013.
3. Aggregation of protein drugs: Risk assessment and mitigation strategies. University of Illinois Chicago, Chicago, IL, January 30, 2013.
4. Aggregation of protein drugs: Risk assessment and mitigation strategies. U.S. Food and Drug Administration, Center for Biologics Evaluation and Research (CBER), Rockville, MD, November 27, 2012.
5. Introduction to the Department of Industrial and Physical Pharmacy. Shenyang Pharmaceutical University, Shenyang, China, September 16, 2012.
6. Degradation of protein drugs: Mechanisms and risk assessment. Pfizer Global Supply Webex, September 4, 2012.
7. Optimizing protein-excipient interactions for the development of aggregation-reducing formulations. Brock C. Roughton, Anthony I. Pokphanh, Elizabeth M. Topp and Kyle V. Camarda, Symposium on Process Systems Engineering (PSE2012), Singapore, July 15-19, 2012. (in preparation)
8. Effects of lyophilization on protein drugs. 2012 Annual Meeting of the Midwest Chapter of the International Society for Lyophilization – Freeze Drying (ISLFD), Chicago, IL, April 12, 2012.
9. Aggregation of protein drugs. University of Kansas, Department of Chemical Engineering, Lawrence, KS, March 6, 2012.
10. Aggregation of protein drugs. University of Connecticut, College of Pharmacy, Storrs, CT, February 1, 2012.
11. Effects of lyophilization on protein chemical and physical properties. Abbott Laboratories, North Chicago, December 8, 2011.
12. Aggregation and stabilization of lyophilized proteins by excipients. Lavanya K. Iyer and Elizabeth M. Topp, Ninth Annual Garnet E. Peck Symposium in Industrial Pharmacy, Purdue University, West Lafayette, IN, October 20, 2011.
13. Thiol disulfide exchange and disulfide scrambling in peptides derived from human growth hormone. Saradha Chandrasekhar, Andreas Sophocleous and Elizabeth M. Topp, Ninth Annual Garnet E. Peck Symposium in Industrial Pharmacy, Purdue University, West Lafayette, IN, October 20, 2011.
14. Investigation of deuterium uptake kinetics in lyophilized myoglobin powders. Andreas Sophocleous and Elizabeth M. Topp, Gordon Research Conference, Biological Molecules in the Gas Phase and in Solution, Andover, NH, July 31-August 5, 2011.
15. Lyophilization-induced aggregation: A survey of structural properties of model proteins. Esben Bertelsen and Elizabeth M. Topp, Colorado Protein Stability Conference, Breckenridge, CO, July 19-21, 2011.
16. Aggregation and stabilization of lyophilized proteins by excipients. Lavanya K. Iyer and Elizabeth M. Topp, Pharmaceutics Graduate Students Research Meeting, Madison, WI, June 23-25, 2011.
17. Lyophilization-induced aggregation of model proteins. Esben Bertelsen and Elizabeth M. Topp. Pharmaceutics Graduate Students Research Meeting, Madison, WI, June 23-25, 2011.
18. Thiol-disulfide exchange and disulfide scrambling in peptides derived from human growth hormone. Saradha Chandresekhar and Elizabeth M. Topp. Pharmaceutics Graduate Students Research Meeting, Madison, WI, June 23-25, 2011.
19. Characterization of disulfide bond scrambling in human growth hormone induced by thermal stress, freeze-thaw cycling, agitation and lyophilization. Jun Zhang, Andreas Sophocleous and Elizabeth M. Topp. American Chemical Society National Meeting, Anaheim, CA, March 27-31, 2011.
20. Hydrogen-deuterium exchange study of myoglobin in solution and solid states. Andreas Sophocleous and Elizabeth M. Topp, Biophysical Society Meeting, Baltimore, MD, March, 2011.
21. Stabilization of human IgGs immobilized onto protein G agarose beads via affinity interaction. Jun Zhang and Elizabeth M. Topp. American Association of Pharmaceutical Scientists Annual Meeting, New Orleans, LA, November 14-18, 2010.
22. Use of aggregation prediction in the design of protein formulations. Brock C. Roughton, Anthony I. Pokphanh, T. Steele Reynolds, Jennifer Laurence, Elizabeth M. Topp, and Kyle.V. Camarda. American Institute of Chemical Engineers Annual Meeting, Salt Lake City, UT, November 7-12, 2010.
23. Stabilization of human IgGs by immobilization on Protein G agarose beads. Jun Zhang and Elizabeth M. Topp. Eighth Annual Garnet E. Peck Symposium in Industrial Pharmacy, Purdue University, West Lafayette, IN, October 14, 2010.
24. Stabilization of human IgGs by immobilization on Protein G agarose beads. Jun Zhang and Elizabeth M. Topp. 2010 Workshop on Protein Aggregation and Immunogenicity, Breckenridge, CO, July 20-22, 2010.
25. Hydrogen-deuterium exchange study of myoglobin in solution and solid states. Andreas Sophocleous and Elizabeth M. Topp, AAPS National Biotechnology Conference, San Francisco, CA, May 16-19, 2010.
26. Aggregation prediction in therapeutic protein formulations for excipient design. Brock C. Roughton, Anthony I. Pokphanh, T. Steele Reynolds, J. Laurence, E.M. Topp and K.V. Camarada. Missouri Regional Life Sciences Summit, Kansas City, MO, March 8-9, 2010.

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