Turnbaugh - Revision history

Peter J. Turnbaugh at 17:38, 17 January 2013

Peter J. Turnbaugh — Thu, 17 Jan 2013 17:38:51 GMT

←Older revision		Revision as of 17:38, 17 January 2013
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	The human ‘metagenome’ is a composite of <i>Homo sapiens</i> genes and the genomes of the trillions of microbes that colonize our adult bodies (the ‘microbiome’). Our largest collection of microbes resides in the gut, where an estimated 10-100 trillion organisms reside (the gut microbiota). The gut microbiome extends human metabolism by enabling the degradation of otherwise indigestible components of our diet, and by influencing the activity, toxicity, and bioavailability of therapeutics. These microbial biotransformations can have important consequences for host health and disease, including contributing to metabolic syndrome, inflammatory bowel disease, and cancer.		The human ‘metagenome’ is a composite of <i>Homo sapiens</i> genes and the genomes of the trillions of microbes that colonize our adult bodies (the ‘microbiome’). Our largest collection of microbes resides in the gut, where an estimated 10-100 trillion organisms reside (the gut microbiota). The gut microbiome extends human metabolism by enabling the degradation of otherwise indigestible components of our diet, and by influencing the activity, toxicity, and bioavailability of therapeutics. These microbial biotransformations can have important consequences for host health and disease, including contributing to metabolic syndrome, inflammatory bowel disease, and cancer.

-	[[Image:F1.~~medium.gif~~\|150px\|\|left\|]]	+	[[Image:MauriceCellCover.jpg\|150px\|\|left\|]]
-	[[Image:~~MauriceCellCover~~.~~jpg~~\|150px\|\|~~middle~~\|]]	+	[[Image:F1.medium.gif\|150px\|\|right\|]]
	Despite the recent surge in human gut microbiome research, a number of basic questions regarding the assembly, structure, and functional operations of the gut microbiome remain unanswered. Our research involves the development and application of metagenomic tools for understanding how the gut microbiome influences drug metabolism and nutrition. We are currently pursuing complementary techniques for cell cytometry, microfluidics, and metabolomics, allowing a more comprehensive view of host-microbial interactions and microbial ecology.		Despite the recent surge in human gut microbiome research, a number of basic questions regarding the assembly, structure, and functional operations of the gut microbiome remain unanswered. Our research involves the development and application of metagenomic tools for understanding how the gut microbiome influences drug metabolism and nutrition. We are currently pursuing complementary techniques for cell cytometry, microfluidics, and metabolomics, allowing a more comprehensive view of host-microbial interactions and microbial ecology.
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Peter J. Turnbaugh at 17:38, 17 January 2013

Peter J. Turnbaugh — Thu, 17 Jan 2013 17:38:23 GMT

←Older revision		Revision as of 17:38, 17 January 2013
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	The human ‘metagenome’ is a composite of <i>Homo sapiens</i> genes and the genomes of the trillions of microbes that colonize our adult bodies (the ‘microbiome’). Our largest collection of microbes resides in the gut, where an estimated 10-100 trillion organisms reside (the gut microbiota). The gut microbiome extends human metabolism by enabling the degradation of otherwise indigestible components of our diet, and by influencing the activity, toxicity, and bioavailability of therapeutics. These microbial biotransformations can have important consequences for host health and disease, including contributing to metabolic syndrome, inflammatory bowel disease, and cancer.		The human ‘metagenome’ is a composite of <i>Homo sapiens</i> genes and the genomes of the trillions of microbes that colonize our adult bodies (the ‘microbiome’). Our largest collection of microbes resides in the gut, where an estimated 10-100 trillion organisms reside (the gut microbiota). The gut microbiome extends human metabolism by enabling the degradation of otherwise indigestible components of our diet, and by influencing the activity, toxicity, and bioavailability of therapeutics. These microbial biotransformations can have important consequences for host health and disease, including contributing to metabolic syndrome, inflammatory bowel disease, and cancer.

-	[[Image:F1.medium.gif\|150px\|\|left\|][Image:MauriceCellCover.jpg\|150px\|\|~~left~~\|]]	+	[[Image:F1.medium.gif\|150px\|\|left\|]]
		+	[[Image:MauriceCellCover.jpg\|150px\|\|middle\|]]
	Despite the recent surge in human gut microbiome research, a number of basic questions regarding the assembly, structure, and functional operations of the gut microbiome remain unanswered. Our research involves the development and application of metagenomic tools for understanding how the gut microbiome influences drug metabolism and nutrition. We are currently pursuing complementary techniques for cell cytometry, microfluidics, and metabolomics, allowing a more comprehensive view of host-microbial interactions and microbial ecology.		Despite the recent surge in human gut microbiome research, a number of basic questions regarding the assembly, structure, and functional operations of the gut microbiome remain unanswered. Our research involves the development and application of metagenomic tools for understanding how the gut microbiome influences drug metabolism and nutrition. We are currently pursuing complementary techniques for cell cytometry, microfluidics, and metabolomics, allowing a more comprehensive view of host-microbial interactions and microbial ecology.
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Peter J. Turnbaugh at 17:38, 17 January 2013

Peter J. Turnbaugh — Thu, 17 Jan 2013 17:38:01 GMT

←Older revision		Revision as of 17:38, 17 January 2013
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	The human ‘metagenome’ is a composite of <i>Homo sapiens</i> genes and the genomes of the trillions of microbes that colonize our adult bodies (the ‘microbiome’). Our largest collection of microbes resides in the gut, where an estimated 10-100 trillion organisms reside (the gut microbiota). The gut microbiome extends human metabolism by enabling the degradation of otherwise indigestible components of our diet, and by influencing the activity, toxicity, and bioavailability of therapeutics. These microbial biotransformations can have important consequences for host health and disease, including contributing to metabolic syndrome, inflammatory bowel disease, and cancer.		The human ‘metagenome’ is a composite of <i>Homo sapiens</i> genes and the genomes of the trillions of microbes that colonize our adult bodies (the ‘microbiome’). Our largest collection of microbes resides in the gut, where an estimated 10-100 trillion organisms reside (the gut microbiota). The gut microbiome extends human metabolism by enabling the degradation of otherwise indigestible components of our diet, and by influencing the activity, toxicity, and bioavailability of therapeutics. These microbial biotransformations can have important consequences for host health and disease, including contributing to metabolic syndrome, inflammatory bowel disease, and cancer.

-	[[Image:F1.medium.gif\|150px\|\|left\|]][[Image:MauriceCellCover.jpg\|150px\|\|left\|]]	+	[[Image:F1.medium.gif\|150px\|\|left\|][Image:MauriceCellCover.jpg\|150px\|\|left\|]]
	Despite the recent surge in human gut microbiome research, a number of basic questions regarding the assembly, structure, and functional operations of the gut microbiome remain unanswered. Our research involves the development and application of metagenomic tools for understanding how the gut microbiome influences drug metabolism and nutrition. We are currently pursuing complementary techniques for cell cytometry, microfluidics, and metabolomics, allowing a more comprehensive view of host-microbial interactions and microbial ecology.		Despite the recent surge in human gut microbiome research, a number of basic questions regarding the assembly, structure, and functional operations of the gut microbiome remain unanswered. Our research involves the development and application of metagenomic tools for understanding how the gut microbiome influences drug metabolism and nutrition. We are currently pursuing complementary techniques for cell cytometry, microfluidics, and metabolomics, allowing a more comprehensive view of host-microbial interactions and microbial ecology.
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Peter J. Turnbaugh at 17:37, 17 January 2013

Peter J. Turnbaugh — Thu, 17 Jan 2013 17:37:50 GMT

←Older revision		Revision as of 17:37, 17 January 2013
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	The human ‘metagenome’ is a composite of <i>Homo sapiens</i> genes and the genomes of the trillions of microbes that colonize our adult bodies (the ‘microbiome’). Our largest collection of microbes resides in the gut, where an estimated 10-100 trillion organisms reside (the gut microbiota). The gut microbiome extends human metabolism by enabling the degradation of otherwise indigestible components of our diet, and by influencing the activity, toxicity, and bioavailability of therapeutics. These microbial biotransformations can have important consequences for host health and disease, including contributing to metabolic syndrome, inflammatory bowel disease, and cancer.		The human ‘metagenome’ is a composite of <i>Homo sapiens</i> genes and the genomes of the trillions of microbes that colonize our adult bodies (the ‘microbiome’). Our largest collection of microbes resides in the gut, where an estimated 10-100 trillion organisms reside (the gut microbiota). The gut microbiome extends human metabolism by enabling the degradation of otherwise indigestible components of our diet, and by influencing the activity, toxicity, and bioavailability of therapeutics. These microbial biotransformations can have important consequences for host health and disease, including contributing to metabolic syndrome, inflammatory bowel disease, and cancer.

-	[[Image:F1.medium.gif\|150px\|\|left\|]]	+	[[Image:F1.medium.gif\|150px\|\|left\|]][[Image:MauriceCellCover.jpg\|150px\|\|left\|]]
-	[[Image:MauriceCellCover.jpg\|150px\|\|left\|]]	+
	Despite the recent surge in human gut microbiome research, a number of basic questions regarding the assembly, structure, and functional operations of the gut microbiome remain unanswered. Our research involves the development and application of metagenomic tools for understanding how the gut microbiome influences drug metabolism and nutrition. We are currently pursuing complementary techniques for cell cytometry, microfluidics, and metabolomics, allowing a more comprehensive view of host-microbial interactions and microbial ecology.		Despite the recent surge in human gut microbiome research, a number of basic questions regarding the assembly, structure, and functional operations of the gut microbiome remain unanswered. Our research involves the development and application of metagenomic tools for understanding how the gut microbiome influences drug metabolism and nutrition. We are currently pursuing complementary techniques for cell cytometry, microfluidics, and metabolomics, allowing a more comprehensive view of host-microbial interactions and microbial ecology.
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Peter J. Turnbaugh at 17:37, 17 January 2013

Peter J. Turnbaugh — Thu, 17 Jan 2013 17:37:36 GMT

←Older revision		Revision as of 17:37, 17 January 2013
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	[[Image:F1.medium.gif\|150px\|\|left\|]]		[[Image:F1.medium.gif\|150px\|\|left\|]]
		+	[[Image:MauriceCellCover.jpg\|150px\|\|left\|]]
	Despite the recent surge in human gut microbiome research, a number of basic questions regarding the assembly, structure, and functional operations of the gut microbiome remain unanswered. Our research involves the development and application of metagenomic tools for understanding how the gut microbiome influences drug metabolism and nutrition. We are currently pursuing complementary techniques for cell cytometry, microfluidics, and metabolomics, allowing a more comprehensive view of host-microbial interactions and microbial ecology.		Despite the recent surge in human gut microbiome research, a number of basic questions regarding the assembly, structure, and functional operations of the gut microbiome remain unanswered. Our research involves the development and application of metagenomic tools for understanding how the gut microbiome influences drug metabolism and nutrition. We are currently pursuing complementary techniques for cell cytometry, microfluidics, and metabolomics, allowing a more comprehensive view of host-microbial interactions and microbial ecology.
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Peter J. Turnbaugh at 13:55, 18 October 2012

Peter J. Turnbaugh — Thu, 18 Oct 2012 13:55:39 GMT

←Older revision		Revision as of 13:55, 18 October 2012
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	[[Image:HomePageImage2.jpg\|400px\|\|right\|]]		[[Image:HomePageImage2.jpg\|400px\|\|right\|]]
-	The human ‘metagenome’ is a composite of <i>Homo sapiens</i> genes and ~~genes present in~~ the genomes of the trillions of microbes that colonize our adult bodies (the ‘microbiome’). Our largest collection of microbes resides in the gut, where an estimated 10-100 trillion organisms reside (the gut microbiota). The gut microbiome ~~encodes metabolic capacities that remain largely unexplored but include~~ the degradation of otherwise indigestible components of our diet~~. Our recent metagenomic analyses of humans~~ and ~~mice have revealed linkages between distal gut microbial ecology~~, ~~microbial community gene content~~, and ~~host energy balance~~. ~~Other studies have also demonstrated links between~~ microbial ~~ecology~~ and ~~human disorders such as Crohn’s~~ disease, ~~ulcerative colitis~~, and ~~diabetes~~.	+	The human ‘metagenome’ is a composite of <i>Homo sapiens</i> genes and the genomes of the trillions of microbes that colonize our adult bodies (the ‘microbiome’). Our largest collection of microbes resides in the gut, where an estimated 10-100 trillion organisms reside (the gut microbiota). The gut microbiome extends human metabolism by enabling the degradation of otherwise indigestible components of our diet, and by influencing the activity, toxicity, and bioavailability of therapeutics. These microbial biotransformations can have important consequences for host health and disease, including contributing to metabolic syndrome, inflammatory bowel disease, and cancer.

	[[Image:F1.medium.gif\|150px\|\|left\|]]		[[Image:F1.medium.gif\|150px\|\|left\|]]
-	Despite the recent surge in human gut microbiome research ~~(e.g. [http://nihroadmap.nih.gov/hmp/ NIH HMP])~~, a number of basic questions regarding the assembly, structure, and functional operations of the gut microbiome remain unanswered. Our research involves the development and application of ~~computational and experimental methods~~ for the ~~analysis of community structure, gene content,~~ and ~~function of complex microbial communities~~. We ~~plan to couple these~~ techniques ~~to additional experimental techniques such as functional metagenomics and <i>in vitro</i>~~ cell ~~culture to study the metabolic functions of the human gut microbiome~~, ~~with potential implications for human health~~ and ~~nutrition~~.	+	Despite the recent surge in human gut microbiome research, a number of basic questions regarding the assembly, structure, and functional operations of the gut microbiome remain unanswered. Our research involves the development and application of metagenomic tools for understanding how the gut microbiome influences drug metabolism and nutrition. We are currently pursuing complementary techniques for cell cytometry, microfluidics, and metabolomics, allowing a more comprehensive view of host-microbial interactions and microbial ecology.
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Peter J. Turnbaugh at 20:08, 21 September 2012

Peter J. Turnbaugh — Fri, 21 Sep 2012 20:08:53 GMT

←Older revision		Revision as of 20:08, 21 September 2012
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Peter J. Turnbaugh at 20:08, 21 September 2012

Peter J. Turnbaugh — Fri, 21 Sep 2012 20:08:23 GMT

←Older revision		Revision as of 20:08, 21 September 2012
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Peter J. Turnbaugh at 20:07, 21 September 2012

Peter J. Turnbaugh — Fri, 21 Sep 2012 20:07:39 GMT

←Older revision		Revision as of 20:07, 21 September 2012
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Peter J. Turnbaugh: Undo revision 580360 by Peter J. Turnbaugh (Talk)

Peter J. Turnbaugh — Fri, 03 Feb 2012 19:25:52 GMT

Undo revision 580360 by Peter J. Turnbaugh (Talk)

←Older revision		Revision as of 19:25, 3 February 2012
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	<div style="font-size: medium; width: 750px;">		<div style="font-size: medium; width: 750px;">
	[[Image:HomePageImage2.jpg\|400px\|\|right\|]]		[[Image:HomePageImage2.jpg\|400px\|\|right\|]]
-	The human ‘metagenome’ is a composite of <i>Homo sapiens</i> genes and genes present in the genomes of the trillions of microbes that colonize our adult bodies (the ‘microbiome’). Our largest collection of microbes resides in the gut, where an estimated 10-100 trillion organisms reside (the gut microbiota). The gut microbiome encodes metabolic capacities that remain largely unexplored but include the degradation of otherwise indigestible components of our diet.	+	The human ‘metagenome’ is a composite of <i>Homo sapiens</i> genes and genes present in the genomes of the trillions of microbes that colonize our adult bodies (the ‘microbiome’). Our largest collection of microbes resides in the gut, where an estimated 10-100 trillion organisms reside (the gut microbiota). The gut microbiome encodes metabolic capacities that remain largely unexplored but include the degradation of otherwise indigestible components of our diet. Our recent metagenomic analyses of humans and mice have revealed linkages between distal gut microbial ecology, microbial community gene content, and host energy balance. Other studies have also demonstrated links between microbial ecology and human disorders such as Crohn’s disease, ulcerative colitis, and diabetes.
		+
	[[Image:F1.medium.gif\|150px\|\|left\|]]		[[Image:F1.medium.gif\|150px\|\|left\|]]
-	~~Our recent metagenomic analyses of humans and mice have revealed linkages between diet, the gut microbiome, and host energy balance. However, despite~~ the recent surge in human gut microbiome research, a number of basic questions regarding the assembly, structure, and functional operations of the gut microbiome remain unanswered. ~~Currently, our major~~ research ~~focus~~ involves the development and application of computational and experimental ~~tools~~ for ~~understanding how~~ the ~~gut microbiome impacts nutrition~~ and ~~drug metabolism~~. ~~Together,~~ these ~~studies may lead~~ to ~~a more comprehensive view~~ of human ~~metabolism~~, ~~and to new strategies~~ for ~~personalized medicine or~~ nutrition.	+	Despite the recent surge in human gut microbiome research (e.g. [http://nihroadmap.nih.gov/hmp/ NIH HMP]), a number of basic questions regarding the assembly, structure, and functional operations of the gut microbiome remain unanswered. Our research involves the development and application of computational and experimental methods for the analysis of community structure, gene content, and function of complex microbial communities. We plan to couple these techniques to additional experimental techniques such as functional metagenomics and <i>in vitro</i> cell culture to study the metabolic functions of the human gut microbiome, with potential implications for human health and nutrition.
	</div>		</div>
	<p>		<p>