Turnbaugh:Research

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==Data==
==Data==
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See [http://gordonlab.wustl.edu/SuppData.html Supplementary Data]
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See Gordon lab website [http://gordonlab.wustl.edu/SuppData.html Supplementary Data]
 +
<br>New data pending...
==Press==
==Press==
[http://www.npr.org/templates/story/story.php?storyId=6654607 National Public Radio spot 2006]
[http://www.npr.org/templates/story/story.php?storyId=6654607 National Public Radio spot 2006]
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[http://www.npr.org/templates/story/story.php?storyId=120318757 National Public Radio spot 2009]
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[http://www.nature.com/news/2006/061218/full/news061218-6.html Nature News 2006]
[http://www.nytimes.com/2006/08/13/magazine/13obesity.html New York Times Fat Factors]
[http://www.nytimes.com/2006/08/13/magazine/13obesity.html New York Times Fat Factors]
[http://www.bryongaskin.net/articles/research/Health/Holly%20Shit%20-%20A%20New%20way%20of%20finding%20out%20how%20diet%20affects%20gut%20microbes.pdf Economist]
[http://www.bryongaskin.net/articles/research/Health/Holly%20Shit%20-%20A%20New%20way%20of%20finding%20out%20how%20diet%20affects%20gut%20microbes.pdf Economist]
 +
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[http://www.npr.org/templates/story/story.php?storyId=120318757 National Public Radio spot 2009]
[http://www.nature.com/news/2010/101124/full/468492a.html Nature News]
[http://www.nature.com/news/2010/101124/full/468492a.html Nature News]
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 +
==Outreach==
 +
[http://www.outreach.mcb.harvard.edu/videos.htm Exploring Biodiversity Lecture]

Revision as of 20:06, 13 June 2011

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Contents

The human gut microbiome

The human ‘metagenome’ is a composite of Homo sapiens genes and genes present in the genomes of the trillions of microbes that colonize our adult bodies (the ‘microbiome’). Our largest collection of microbes resides in the gut, where an estimated 10-100 trillion organisms reside (the gut microbiota). The gut microbiome encodes metabolic capacities that remain largely unexplored but include the degradation of otherwise indigestible components of our diet. Our recent metagenomic analyses of humans and mice have revealed linkages between distal gut microbial ecology, microbial community gene content, and host energy balance. Other studies have also demonstrated links between microbial ecology and human disorders such as Crohn’s disease, ulcerative colitis, and diabetes.

Despite the recent surge in human gut microbiome research NIH HMP, a number of basic questions regarding the assembly, structure, and functional operations of the gut microbiome remain unanswered. Our research involves the development and application of computational and experimental methods for the analysis of community structure, gene content, and function of complex microbial communities. We plan to couple these techniques to additional experimental techniques such as functional metagenomics and in vitro cell culture to study the metabolic functions of the human gut microbiome, with potential implications for human health and nutrition.

Data

See Gordon lab website Supplementary Data
New data pending...

Press

National Public Radio spot 2006

Nature News 2006

New York Times Fat Factors

Economist

National Public Radio spot 2009

Nature News

Outreach

Exploring Biodiversity Lecture
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