User:A. Florian Sessler
From OpenWetWare
(added a link to Imperial iGEM site) |
(Added section about Cell state reporters) |
||
| Line 15: | Line 15: | ||
Currently doing my bachelor in Biology with Microbiology at Imperial College London. | Currently doing my bachelor in Biology with Microbiology at Imperial College London. | ||
| - | == | + | ==Cell State Reporters== |
| - | + | * | |
| + | Monitoring Cell Activity might be very useful for scientists in many situations. We propose the use of '''Cell State Reporters''' to quickly give visual information of the activities or phase the cells are undergoing which could be achieved by using elements that control expression of state specific genes. This might help to maintain a healthy population and to determine whether population grows anaerobically or aerobically. Furthermore it could be used as a warning signal when cells undergo undesired/stressful phases and to examine if the cells grow in synchrony. Many different regulon systems could potentially exploited for this purpose including without limitation: Ntr and Nif system that detect ammonia limitation, Arc and Fnr system that detect anaerobic conditions, the SOS and response to UV light, sporulation in response to starvation and the heat shock response. | ||
==Publications== | ==Publications== | ||
Revision as of 06:45, 7 July 2010
Contents |
Contact Info
- A. Florian Sessler
- Imperial College London
- Email me through OpenWetWare
I am a member of the iGEM 2010 twam of Imperial College London. I learned about OpenWetWare from the project organiser of my team who told us about this site which we will be using during the following months.
Education
Currently doing my bachelor in Biology with Microbiology at Imperial College London.
Cell State Reporters
Monitoring Cell Activity might be very useful for scientists in many situations. We propose the use of Cell State Reporters to quickly give visual information of the activities or phase the cells are undergoing which could be achieved by using elements that control expression of state specific genes. This might help to maintain a healthy population and to determine whether population grows anaerobically or aerobically. Furthermore it could be used as a warning signal when cells undergo undesired/stressful phases and to examine if the cells grow in synchrony. Many different regulon systems could potentially exploited for this purpose including without limitation: Ntr and Nif system that detect ammonia limitation, Arc and Fnr system that detect anaerobic conditions, the SOS and response to UV light, sporulation in response to starvation and the heat shock response.



