User:Adam B. Fisher

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As a researcher, I am broadly interested in integrating approaches and technologies found in synthetic and systems biology, metabolic engineering, bioinformatics and quantitative biology to facilitate microbial engineering. As an undergraduate at Virginia Tech concentrating in Microbiology and Immunology, I had my first exposure to these emergent fields while working as an undergraduate researcher in the laboratory of [[Jean_Peccoud|Dr. Jean Peccoud]]. I worked alongside [[Matthew_W_Lux|Matthew Lux]] to build out and characterize a bi-stable genetic toggle switch. Subsequently, I joined the [[Fong]] lab at Virginia Commonwealth University to begin my PhD in Integrative Life Sciences. My research interests include:
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As a researcher, I am broadly interested in integrating approaches and technologies found in synthetic and systems biology, metabolic engineering, bioinformatics and quantitative biology to facilitate microbial engineering. As an undergraduate at Virginia Tech concentrating in Microbiology and Immunology, I had my first exposure to these emergent fields while working as an undergraduate researcher in the laboratory of [[Jean_Peccoud|Dr. Jean Peccoud]]. I worked alongside [[Matthew_W_Lux|Matthew Lux]] to build out and characterize a bi-stable genetic toggle switch. Subsequently, I joined the [[Fong]] lab at Virginia Commonwealth University to begin my PhD in Integrative Life Sciences. Here my research interests have expanded include:
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*Cell Free Systems
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*Orthogonal gene expression
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*Synthetic gene assembly
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*Artificial gene networks
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*Protein engineering
*Synthetic metagenomics
*Synthetic metagenomics
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*Genome organization, refactoring & design
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*Genome-scale metabolic models
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*Metabolic, organellar & enzyme engineering
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*Statistical models of biological sequences
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*Genome-scale, single-cell characterization
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*Engineered microbial consortia
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==Education & Training==
==Education & Training==
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'''Imperial College London ·''' ''London, UK'' '''·''' 2011 — 2012
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'''Virginia Commonwealth University ·''' ''Richmond, VA'' '''·''' 2011 2014
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*Whitaker International Fellow '''·''' Bioengineering
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*Ph.D. '''·''' Integrative Life Sciences
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**Advised by Travis S. Bayer
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'''Virginia Commonwealth University ·''' ''Richmond, VA'' '''·''' 2008 2013
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*Ph.D. '''·''' Chemical and Biological Engineering
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**Advised by Stephen S. Fong
**Advised by Stephen S. Fong
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*M.S. '''·''' Chemical Engineering
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'''Virginia Tech ·''' ''Blacksburg, VA'' '''·''' 2007 2011
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*B.S. '''·''' Biological Sciences
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'''University of Virginia ·''' ''Charlottesville, VA'' '''·''' 2002 2008
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**Concentration in Microbiology & Immunology
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*B.S. '''·''' Chemical Engineering
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*Minor '''·''' Business
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**Advised by Erik J. Fernandez and Jason A. Papin
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*B.A. '''·''' Music
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*Minor '''·''' Biology
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==Publications==
==Publications==
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*G.H. McArthur 4th and S.S. Fong. (2013). Modulating gene expression with designed UP elements. In preparation.
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*Vanee N, '''Fisher A''', Fong S. “Evolutionary Engineering for Industrial Microbiology”. Subcellular Biochemistry: Reprogramming Microbial Metabolic Pathways (New York: Springer Verlag, 2012), Vol. 64.  
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*M. Montague, G.H. McArthur 4th, C.S. Cockell, J. Held, W. Marshall, L.A. Sherman, N. Wang, W.L. Nicholoson, D. Tarjan and J. Cumbers. (2012). [http://online.liebertpub.com/doi/abs/10.1089/ast.2012.0829 The role of synthetic biology for in situ resource utilization (ISRU)]. ''Astrobiology''.
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*G.H. McArthur 4th and S.S. Fong. (2010). [http://www.hindawi.com/journals/jbb/2010/459760.abs.html Toward engineering synthetic microbial metabolism]. ''J. Biomed. Biotechnol.'' doi:10.1155/2010/459760.
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==Presentations==
==Presentations==
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*Poster - Predictable gene expression using extended promoters and orthogonal cellular machinery, Cell factories and Biosustainability. Favrholm, Copenhagen, DK, 5-8 May 2013
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*Poster - DNA Assembly for free: using cellular lysates to decrease cloning costs, Synthetic Biology 6.0. Imperial College of London, UK 9-12 July 2013
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*Poster - The development of a genetically encoded, function-based taxol biosensor, Metabolic Engineering IX. Biarritz, FR, 3-7 June 2012
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*Talk/Poster - Cyanobacteria: A sustainable manufacturing platform, iGEM Americas Regional Jamboree. Indiana University Purdue University Indianapolis, Indianapolis, IN, 8-10 October 2011
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*Poster - An orthogonal transcription platform for fine-tuning gene expression, Synthetic Biology 5.0. Stanford University, Stanford, CA, 15-17 June 2011
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*Poster (invited) - A synthetic platform for controlling gene expression, Workshop: What are the potential roles of synthetic biology in NASA's mission?, 30-31 October 2010, NASA Ames Center, Moffett Field, CA
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*Poster - Modulating gene expression in ''Escherichia coli'' with synthetic UP elements, BIOFAB 2010 Community Meeting, 19-20 July 2010, Emeryville, CA
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*Poster - Modulating gene expression in ''Escherichia coli'' with synthetic UP elements, ASM 2010, 23-27 May 2010, San Diego, CA
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*Poster - ''Chlamydomonas reinhardtii'' as a photosynthetic cellular chassis and power supply for synthetic biological systems, BioSysBio 2009, 23-25 March 2009, Cambridge University, Cambridge, UK
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*Poster - ''Chlamydomonas reinhardtii'' as a platform for the direct photosynthesis of advanced biofuels, Institute of Biological Engineering 2009 annual meeting, 19-22 March 2009, Santa Clara, CA
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*Poster - A bottom-up approach to synthetic biology education: From iGEM teams to undergraduate curricula, Synthetic Biology 4.0, 10-12 October 2008, HKUST, Hong Kong, China
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*Talk - [http://tv.theiet.org/technology/electronics/1199.cfm The Virginia Genetically Engineered Machine Team], BioSysBio 2008, 20-22 April 2008, Imperial College London, London, UK
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*Poster - Harvesting cellulose and light to power butanol biosynthesis: A synthetic biology approach to metabolic engineering, Institute of Biological Engineering 2008 annual meeting, 6-9 March 2008, Chapel Hill, NC
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*Talk/poster - Harvesting cellulose and light to power butanol biosynthesis: A synthetic biology approach to metabolic engineering, iGEM 2007, 3-4 November 2007, MIT, Cambridge, MA
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Revision as of 22:26, 1 July 2013

·

Adam B. Fisher

Adam Fisher candidly enjoying his morning coffee
Adam Fisher candidly enjoying his morning coffee

In nature hybrid species are usually sterile, but in science the reverse is often true.
Hybrid subjects are often astonishingly fertile, whereas if a scientific discipline remains too pure it usually wilts.
- Francis Crick



What I cannot create, I cannot understand.
- Richard Feynman



I am very comfortable with the idea that we can override biology with free will.
- Richard Dawkins



As a researcher, I am broadly interested in integrating approaches and technologies found in synthetic and systems biology, metabolic engineering, bioinformatics and quantitative biology to facilitate microbial engineering. As an undergraduate at Virginia Tech concentrating in Microbiology and Immunology, I had my first exposure to these emergent fields while working as an undergraduate researcher in the laboratory of Dr. Jean Peccoud. I worked alongside Matthew Lux to build out and characterize a bi-stable genetic toggle switch. Subsequently, I joined the Fong lab at Virginia Commonwealth University to begin my PhD in Integrative Life Sciences. Here my research interests have expanded include:

  • Cell Free Systems
  • Synthetic gene assembly
  • Protein engineering
  • Synthetic metagenomics
  • Genome-scale metabolic models
  • Statistical models of biological sequences
  • Engineered microbial consortia


Education & Training

Virginia Commonwealth University · Richmond, VA · 2011 — 2014

  • Ph.D. · Integrative Life Sciences
    • Advised by Stephen S. Fong

Virginia Tech · Blacksburg, VA · 2007 — 2011

  • B.S. · Biological Sciences
    • Concentration in Microbiology & Immunology
  • Minor · Business


Publications

  • Vanee N, Fisher A, Fong S. “Evolutionary Engineering for Industrial Microbiology”. Subcellular Biochemistry: Reprogramming Microbial Metabolic Pathways (New York: Springer Verlag, 2012), Vol. 64.


Presentations

  • Poster - DNA Assembly for free: using cellular lysates to decrease cloning costs, Synthetic Biology 6.0. Imperial College of London, UK 9-12 July 2013
  • Talk/Poster - Cyanobacteria: A sustainable manufacturing platform, iGEM Americas Regional Jamboree. Indiana University Purdue University Indianapolis, Indianapolis, IN, 8-10 October 2011




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