User:Adam B. Fisher: Difference between revisions

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[[Image:Afishinlab.jpg|thumb|225px|left|Candidly counting some colonies]]
[[Image:Afishinlab.jpg|thumb|225px|left|Candidly counting colonies]]
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'''''In nature hybrid species are usually sterile, but in science the reverse is often true.''''' <br />
'''''In nature hybrid species are usually sterile, but in science the reverse is often true.''''' <br />
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As a researcher, I am broadly interested in integrating approaches and technologies found in synthetic and systems biology, metabolic engineering, chemical biology and quantitative biology to facilitate microbial engineering. At Virginia Tech, I had my first exposure to these emergent fields while working as an undergraduate to build out and characterize a bi-stable genetic toggle switch. Subsequently, I joined the lab of [[Fong|Dr. Stephen Fong]] at Virginia Commonwealth University endeavoring toward a PhD in Integrative Life Sciences. Currently, I am involved in projects revolving around ''ex vivo'' approaches for cloning and synthetic biology, a synthetic biomolecular delivery system and a cost analysis for the interpretation of genome-scale models. My overall research interests include:
As a researcher, I am broadly interested in integrating approaches and technologies found in synthetic and systems biology, metabolic engineering, chemical biology and quantitative biology to facilitate microbial engineering. At Virginia Tech, I had my first exposure to these emergent fields while working as an undergraduate to build out and characterize a bi-stable genetic toggle switch. Subsequently, I joined the lab of [[Fong|Dr. Stephen Fong]] at Virginia Commonwealth University endeavoring toward a PhD in Integrative Life Sciences. Currently, I am involved in projects involving ''ex vivo'' approaches for cloning and synthetic biology, a synthetic biomolecular delivery system and a cost analysis for the interpretation of genome-scale models. My research interests include:
<br />
<br />
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*Cell Free Systems
*Cell-Free and ''ex vivo'' approaches to molecular biology and biotechnology
*Synthetic gene assembly
*Genome engineering and high-throughput cloning
*Global physiology and single-cell characterization
*Development of engineering platforms for exotic microorganisms
*Engineered microbial consortia and microbiota
*Synthetic metagenomics
*Protein engineering
*Protein engineering
*Synthetic metagenomics
*Construction and simulation of genome-scale models
*Genome-scale metabolic models
*Statistical modeling of biological sequences
*Statistical models of biological sequences
*Engineered microbial consortia
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==Education & Training==
==Education & Training==
'''Virginia Commonwealth University ·''' ''Richmond, VA'' '''·''' 2011 — 2014
'''Virginia Commonwealth University ·''' ''Richmond, VA'' '''·''' 2011 — 2015
*Ph.D. '''·''' Integrative Life Sciences
*Ph.D. '''·''' Integrative Life Sciences
**Advised by Stephen S. Fong
**Advised by Stephen S. Fong
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*Minor '''·''' Business
*Minor '''·''' Business
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==Publications==
==Publications==
*'''Fisher, A. B.''', Canfield, Z. B., Hayward, L. C. & Fong, S. ex vivo DNA assembly. Fronteirs in Bioengineering and Biotechnology (2013). doi:10.3389/fbioe.2013.00012 <br/>
*Yu Deng, '''Fisher, AB''' and Fong, SS. "Systematic analysis of intracellular mechanisms of propanol production in the engineered ''Thermobifida fusca'' B6 strain". Applied Microbiology and Biotechnology (2015) doi:10.1007/s00253-015-6850-4[http://dx.doi.org/10.1007/s00253-015-6850-4]<br/>
*Vanee N, '''Fisher AB''', Fong SS. “Evolutionary Engineering for Industrial Microbiology”. Subcellular Biochemistry: Reprogramming Microbial Metabolic Pathways (New York: Springer Verlag, 2012), Vol. 64.
*'''Fisher, AB''' and Fong, SS. "Lignin biodegradation and industrial implications". AIMS Bioengineering (2014). 1(2): 92-112. doi:10.3934/bioeng.2014.2.92 [http://www.aimspress.com/aimsboa/ch/reader/view_abstract.aspx?file_no=Bioeng09&flag=1]<br/>
*'''Fisher, AB''', Canfield, ZB, Hayward, LC, Fong, SS & McArthur IV, GM. "Ex vivo DNA assembly". Frontiers in Bioengineering and Biotechnology (2013). doi:10.3389/fbioe.2013.00012 [http://journal.frontiersin.org/Journal/10.3389/fbioe.2013.00012/full]<br/>
*'''Fisher AB''', Vanee N, & Fong SS. “Evolutionary Engineering for Industrial Microbiology”. Subcellular Biochemistry: Reprogramming Microbial Metabolic Pathways (New York: Springer Verlag, 2012), Vol. 64. doi:10.1007/978-94-007-5055-5_3. [http://link.springer.com/chapter/10.1007/978-94-007-5055-5_3]
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Latest revision as of 12:54, 31 August 2015

[link title]·

Adam B. Fisher

Candidly counting colonies

In nature hybrid species are usually sterile, but in science the reverse is often true.
Hybrid subjects are often astonishingly fertile, whereas if a scientific discipline remains too pure it usually wilts.
- Francis Crick


What I cannot create, I cannot understand.
- Richard Feynman



I am very comfortable with the idea that we can override biology with free will.
- Richard Dawkins



As a researcher, I am broadly interested in integrating approaches and technologies found in synthetic and systems biology, metabolic engineering, chemical biology and quantitative biology to facilitate microbial engineering. At Virginia Tech, I had my first exposure to these emergent fields while working as an undergraduate to build out and characterize a bi-stable genetic toggle switch. Subsequently, I joined the lab of Dr. Stephen Fong at Virginia Commonwealth University endeavoring toward a PhD in Integrative Life Sciences. Currently, I am involved in projects involving ex vivo approaches for cloning and synthetic biology, a synthetic biomolecular delivery system and a cost analysis for the interpretation of genome-scale models. My research interests include:

  • Cell-Free and ex vivo approaches to molecular biology and biotechnology
  • Genome engineering and high-throughput cloning
  • Global physiology and single-cell characterization
  • Development of engineering platforms for exotic microorganisms
  • Engineered microbial consortia and microbiota
  • Synthetic metagenomics
  • Protein engineering
  • Construction and simulation of genome-scale models
  • Statistical modeling of biological sequences


Education & Training

Virginia Commonwealth University · Richmond, VA · 2011 — 2015

  • Ph.D. · Integrative Life Sciences
    • Advised by Stephen S. Fong

Virginia Tech · Blacksburg, VA · 2007 — 2011

  • B.S. · Biological Sciences
    • Concentration in Microbiology & Immunology
  • Minor · Business


Publications

  • Yu Deng, Fisher, AB and Fong, SS. "Systematic analysis of intracellular mechanisms of propanol production in the engineered Thermobifida fusca B6 strain". Applied Microbiology and Biotechnology (2015) doi:10.1007/s00253-015-6850-4[1]
  • Fisher, AB and Fong, SS. "Lignin biodegradation and industrial implications". AIMS Bioengineering (2014). 1(2): 92-112. doi:10.3934/bioeng.2014.2.92 [2]
  • Fisher, AB, Canfield, ZB, Hayward, LC, Fong, SS & McArthur IV, GM. "Ex vivo DNA assembly". Frontiers in Bioengineering and Biotechnology (2013). doi:10.3389/fbioe.2013.00012 [3]
  • Fisher AB, Vanee N, & Fong SS. “Evolutionary Engineering for Industrial Microbiology”. Subcellular Biochemistry: Reprogramming Microbial Metabolic Pathways (New York: Springer Verlag, 2012), Vol. 64. doi:10.1007/978-94-007-5055-5_3. [4]


Presentations

  • Poster - DNA Assembly for free: using cellular lysates to decrease cloning costs, Synthetic Biology 6.0. Imperial College of London, UK 9-12 July 2013
  • Talk/Poster - Cyanobacteria: A sustainable manufacturing platform, iGEM Americas Regional Jamboree. Indiana University Purdue University Indianapolis, Indianapolis, IN, 8-10 October 2011


Intellectual Property

  • Fisher AB, Brooks JP, Fong SS (2013) Cellular Strain Design Using Large-Scale Cost Analysis (Virginia Commonwealth University)



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