User:Adam B. Fisher
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Adam B. Fisher |
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In nature hybrid species are usually sterile, but in science the reverse is often true.
Hybrid subjects are often astonishingly fertile, whereas if a scientific discipline remains too pure it usually wilts.
- Francis Crick
What I cannot create, I cannot understand.
- Richard Feynman
I am very comfortable with the idea that we can override biology with free will.
- Richard Dawkins
As a researcher, I am broadly interested in integrating approaches and technologies found in synthetic and systems biology, metabolic engineering, bioinformatics and quantitative biology to facilitate microbial engineering. As an undergraduate at Virginia Tech concentrating in Microbiology and Immunology, I had my first exposure to these emergent fields while working as an undergraduate researcher in the laboratory of Dr. Jean Peccoud. I worked alongside Matthew Lux to build out and characterize a bi-stable genetic toggle switch. Subsequently, I joined the Fong lab at Virginia Commonwealth University to begin my PhD in Integrative Life Sciences. My research interests include:
- Orthogonal gene expression
- Artificial gene networks
- Synthetic metagenomics
- Genome organization, refactoring & design
- Metabolic, organellar & enzyme engineering
- Genome-scale, single-cell characterization
Education & Training
Imperial College London · London, UK · 2011 — 2012
- Whitaker International Fellow · Bioengineering
- Advised by Travis S. Bayer
Virginia Commonwealth University · Richmond, VA · 2008 — 2013
- Ph.D. · Chemical and Biological Engineering
- Advised by Stephen S. Fong
- M.S. · Chemical Engineering
University of Virginia · Charlottesville, VA · 2002 — 2008
- B.S. · Chemical Engineering
- Advised by Erik J. Fernandez and Jason A. Papin
- B.A. · Music
- Minor · Biology
Publications
- G.H. McArthur 4th and S.S. Fong. (2013). Modulating gene expression with designed UP elements. In preparation.
- M. Montague, G.H. McArthur 4th, C.S. Cockell, J. Held, W. Marshall, L.A. Sherman, N. Wang, W.L. Nicholoson, D. Tarjan and J. Cumbers. (2012). The role of synthetic biology for in situ resource utilization (ISRU). Astrobiology.
- G.H. McArthur 4th and S.S. Fong. (2010). Toward engineering synthetic microbial metabolism. J. Biomed. Biotechnol. doi:10.1155/2010/459760.
Presentations
- Poster - Predictable gene expression using extended promoters and orthogonal cellular machinery, Cell factories and Biosustainability. Favrholm, Copenhagen, DK, 5-8 May 2013
- Poster - The development of a genetically encoded, function-based taxol biosensor, Metabolic Engineering IX. Biarritz, FR, 3-7 June 2012
- Poster - An orthogonal transcription platform for fine-tuning gene expression, Synthetic Biology 5.0. Stanford University, Stanford, CA, 15-17 June 2011
- Poster (invited) - A synthetic platform for controlling gene expression, Workshop: What are the potential roles of synthetic biology in NASA's mission?, 30-31 October 2010, NASA Ames Center, Moffett Field, CA
- Poster - Modulating gene expression in Escherichia coli with synthetic UP elements, BIOFAB 2010 Community Meeting, 19-20 July 2010, Emeryville, CA
- Poster - Modulating gene expression in Escherichia coli with synthetic UP elements, ASM 2010, 23-27 May 2010, San Diego, CA
- Poster - Chlamydomonas reinhardtii as a photosynthetic cellular chassis and power supply for synthetic biological systems, BioSysBio 2009, 23-25 March 2009, Cambridge University, Cambridge, UK
- Poster - Chlamydomonas reinhardtii as a platform for the direct photosynthesis of advanced biofuels, Institute of Biological Engineering 2009 annual meeting, 19-22 March 2009, Santa Clara, CA
- Poster - A bottom-up approach to synthetic biology education: From iGEM teams to undergraduate curricula, Synthetic Biology 4.0, 10-12 October 2008, HKUST, Hong Kong, China
- Talk - The Virginia Genetically Engineered Machine Team, BioSysBio 2008, 20-22 April 2008, Imperial College London, London, UK
- Poster - Harvesting cellulose and light to power butanol biosynthesis: A synthetic biology approach to metabolic engineering, Institute of Biological Engineering 2008 annual meeting, 6-9 March 2008, Chapel Hill, NC
- Talk/poster - Harvesting cellulose and light to power butanol biosynthesis: A synthetic biology approach to metabolic engineering, iGEM 2007, 3-4 November 2007, MIT, Cambridge, MA
| Research | Teaching |
