User:Alexandra Sobeck
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SOBECK LAB
Contact Info
- Alexandra Sobeck
- Assistant professor, University of Minnesota, Minneapolis
- 420 Washington Ave SE, MCB 6-112
- Minneapolis, MN 55455
- asobeck@umn.edu
We just started our new lab in Jan 2009, and will use OWW to create our own fun lab homepage for introducing ourselves + our research, sharing protocols, scheduling lab meetings, etc...
People
more info coming soon ...
Education
- Year, PhD, Institute
- Year, MS, Institute
- Year, BS, Institute
Research interests
- Interest 1
- Interest 2
- Interest 3
Photos
- In the lab
Published Articles
- Landais I*, Sobeck A*, Stone S*, LaChapelle A, Hoatlin ME (2008): A novel cell-free screen identifies a potent inhibitor of the Fanconi anemia pathway. Int. J. Cancer, in press. (Cover)
- Xu D*, Guo R*, Sobeck A, Bachrati CZ, Yang J, Enomoto T, Brown GW, Hoatlin ME, Hickson ID, Wang W (2008): RMI, a new OB-fold complex essential for Bloom syndrome protein to maintain genome stability. Genes Dev 22: 2843-55.
- Sobeck A, Stone S, Hoatlin ME (2007): DNA Structure-Induced Recruitment and Activation of the Fanconi Anemia Pathway Protein, FANCD2. Mol Cell Biol 27: 4283-92.
- Stone S, Sobeck A, Margriet van Kogelenberg, Bendert de Graaf, Hans Joenje, Jan Christian, Hoatlin ME (2007): Identification, Developmental Expression, and Regulation of the Xenopus Ortholog of Human FANCG/XRCC9. Genes Cells, 12: 841-51.
- Sobeck A*, Stone S*, Costanzo V, de Graaf B, Reuter T, de Winter J, Wallisch M, Akkari Y, Olson S, Wang W, Joenje H, Christian JL, Lupardus PJ, Cimprich KA, Gautier J, Hoatlin ME (2006): Fanconi anemia proteins are required to prevent accumulation of replication-associated DNA double-strand breaks. Mol Cell Biol 26: 425-37. (Cover)
- Yin J*, Sobeck A*, Xu C*, Meetei AR, Hoatlin M, Li L, Wang W (2005): BLAP75, an essential component of Bloom's syndrome protein complexes that maintain genome integrity. EMBO J. 24: 1465-76.
- Leveille F, Blom E, Medhurst AL, Bier P, Laghmani el H, Johnson M, Rooimans MA, Sobeck A, Waisfisz Q, Arwert F, Patel KJ, Hoatlin ME, Joenje H, de Winter JP (2004): The Fanconi anemia gene product FANCF is a flexible adaptor protein. J Biol Chem. 279: 39421-30.
- U. Oppitz, U. Bernthaler, D. Schindler, A. Sobeck, H. Hoehn, M. Platzer, A. Rosenthal, and M Flentje (1999): Sequence Analysis of the ATM Gene in 20 Patients with RTOG grade 3 or 4 Acute and/or Late Tissue Radiation Side Effects. Int. J. Radiation Oncology Biol. Phys. 44, 981-988.
- K.J. Erb, J.W. Holloway, A. Sobeck, H. Moll, G. Le Gros (1998): Infection of mice with Mycobacterium bovis-Bacillus Calmette-Guerin (BCG) suppresses allergen-induced airway eosinophilia. J Exp Med 187:561-9.
