User:Alexis Courbet: Difference between revisions

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[[Image:Alexis_Courbet.jpg|thumb|right|Alexis Courbet]]
[[Image:Alexis_Courbet.jpg|thumb|right|Alexis Courbet]]


# Biocomputing
* Biocomputing
# Cellular/molecular engineering
* Cellular/molecular engineering
# Biosensing systems
* Biosensing systems
# Synthetic gene circuits
* Synthetic biological circuits
# Synthetic biochemical circuits
* CAD for synthetic biology
# CAD for synthetic biology
* Autonomous & programmable biosystems
# Protocells & minimal systems
* Protocells & minimal systems
# Microfluidics  
* Microfluidics  
# Translational medicine and diagnosis
* Medical sciences, translational medicine and diagnosis
# Multidisciplinary science
* Multidisciplinary science
* Biomolecular prosthetics,theranostics&vectors
 


During my PhD, I applied synthetic biology to human health and biotechnology.
During my PhD, I applied synthetic biology to human health and biotechnology.


I developped concepts, systematic methods, computational tools and biological standards to:
I developped concepts, systematic methods, computational tools and biological standards to:
1. Engineer next-generation diagnostics. I engineered autonomous and programmable biosensors integrating multiplexed pathological biomarker detection and complex biological signal processing to develop intelligent diagnostic devices.
1. Engineer next-generation diagnostics. I engineered autonomous and programmable biosensors integrating multiplexed pathological biomarker detection and complex biological signal processing as ''intelligent'' diagnostic devices.


2. Engineer novel biocomputing devices that solve complex problems and process/interface biological information at the microscale. I developed microfluidic and computer assisted methodologies to program these synthetic biosystems from the bottum-up.
2. Engineer novel biocomputing devices that solve complex problems and process/interface biological information at the microscale. I developed microfluidic and computer assisted methodologies to program these synthetic biosystems from the bottum-up (e.g. protocells).


I believe that collaboration between scientists and promotion of interdisciplinarity is the key to understand and engineer biology.
I believe that collaboration between scientists and promotion of interdisciplinarity is the key to understand and engineer biology.

Revision as of 09:15, 29 July 2015

Research interests

Alexis Courbet
  • Biocomputing
  • Cellular/molecular engineering
  • Biosensing systems
  • Synthetic biological circuits
  • CAD for synthetic biology
  • Autonomous & programmable biosystems
  • Protocells & minimal systems
  • Microfluidics
  • Medical sciences, translational medicine and diagnosis
  • Multidisciplinary science
  • Biomolecular prosthetics,theranostics&vectors


During my PhD, I applied synthetic biology to human health and biotechnology.

I developped concepts, systematic methods, computational tools and biological standards to: 1. Engineer next-generation diagnostics. I engineered autonomous and programmable biosensors integrating multiplexed pathological biomarker detection and complex biological signal processing as intelligent diagnostic devices.

2. Engineer novel biocomputing devices that solve complex problems and process/interface biological information at the microscale. I developed microfluidic and computer assisted methodologies to program these synthetic biosystems from the bottum-up (e.g. protocells).

I believe that collaboration between scientists and promotion of interdisciplinarity is the key to understand and engineer biology.

Contact Info

  • Alexis Courbet
  • Sys2diag laboratory, CNRS

Complex biological systems modelling and engineering for diagnosis

Education

  • 2012-2015, PhD at The National Center for Scientific Research (CNRS)&Bio-Rad/Stanford University
  • 2012, MS in Molecular and Cellular Biophysics, University of Montpellier
  • 2011-2015, Residency in Clinical Toxicology, Pharmaceutical innovation and Research
  • 2011, MS in Cellular and Molecular Biology, University Paris Sud 11
  • 2010, BS, University of Paris Sud 11
  • 2010, BMSc, University of Paris Sud 11

Publications

Detection of pathological biomarkers in human clinical samples via amplifying genetic switches and logic gates
Science Translational Medicine, 2015 May 27;7(289):289ra83
Alexis Courbet, Drew Endy, Eric Renard, Franck Molina, and Jérôme Bonnet Abstract PDF
Supplementary Materials

Computing with Synthetic Protocells
Acta Biotheor., 2015 May 13;
Alexis Courbet, Patrick Amar, and Franck Molina Abstract PDF

Engineering next generation diagnostics through synthetic biology
University of Montpellier, Medical Thesis, 2015 July 2;
Alexis Courbet PDF

Useful links