User:Alexis Courbet: Difference between revisions
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* Biocomputing & Biosensing | * Biocomputing & Biosensing | ||
* Synthetic biological circuits | * Synthetic biological circuits | ||
* CAD for synthetic biology | * CAD & computational design for synthetic biology | ||
* Autonomous & programmable biosystems | * Autonomous & programmable biosystems | ||
* Protocells & minimal systems | * Protocells & minimal systems | ||
Revision as of 09:22, 29 July 2015
Research interests
- Cellular/molecular engineering
- Biocomputing & Biosensing
- Synthetic biological circuits
- CAD & computational design for synthetic biology
- Autonomous & programmable biosystems
- Protocells & minimal systems
- Microfluidics
- Biomolecular prosthetics, diagnostics & theranostics
- Medical sciences, translational medicine
- Multidisciplinary science
During my PhD, I applied synthetic biology to human health and biotechnology.
I developped concepts, systematic methods, computational tools and biological standards to:
- 1. Engineer next-generation diagnostics. I engineered autonomous and programmable biosensors integrating multiplexed pathological biomarker detection and complex biological signal processing as intelligent diagnostic devices.
- 2. Engineer novel biocomputing devices that solve complex problems and process/interface biological information at the microscale. I developed microfluidic and computer assisted methodologies to program these synthetic biosystems from the bottum-up (e.g. protocells).
I believe that collaboration between scientists and promotion of interdisciplinarity is the key to understand and engineer biology.
Contact Info
- Alexis Courbet
- Sys2diag laboratory, CNRS
Complex biological systems modelling and engineering for diagnosis
- Montpellier, France
- Email me through OpenWetWare
Education
- 2012-2015, PhD at The National Center for Scientific Research (CNRS)&Bio-Rad/Stanford University
- 2012, MS in Molecular and Cellular Biophysics, University of Montpellier
- 2011-2015, Residency in Clinical Toxicology, Pharmaceutical innovation and Research
- 2011, MS in Cellular and Molecular Biology, University Paris Sud 11
- 2010, BS, University of Paris Sud 11
- 2010, BMSc, University of Paris Sud 11
Publications
Detection of pathological biomarkers in human clinical samples via amplifying genetic switches and logic gates
Science Translational Medicine, 2015 May 27;7(289):289ra83
Alexis Courbet, Drew Endy, Eric Renard, Franck Molina, and Jérôme Bonnet
Abstract PDF
Supplementary Materials
Computing with Synthetic Protocells
Acta Biotheor., 2015 May 13;
Alexis Courbet, Patrick Amar, and Franck Molina
Abstract PDF
Engineering next generation diagnostics through synthetic biology
University of Montpellier, Medical Thesis, 2015 July 2;
Alexis Courbet
PDF
