User:Andreat - Revision history

http://www.openwetware.org/index.php?title=User:Andreat&feed=atom&action=history User:Andreat - Revision history 2013-05-25T03:55:05Z Revision history for this page on the wiki MediaWiki 1.13.2 http://www.openwetware.org/index.php?title=User:Andreat&diff=95277&oldid=prev Andreat at 18:29, 25 January 2007 2007-01-25T18:29:05Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 18:29, 25 January 2007</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 12:</td> <td colspan="2" class="diff-lineno">Line 12:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>===Currently..===</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>===Currently..===</div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>I am the TA for module 3 (Expression Engineering) of [[20.109]], the introductory lab course for declared BE undergrad majors</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>I am the TA for <ins class="diffchange diffchange-inline">[[20.109:Module 3|</ins>module 3<ins class="diffchange diffchange-inline">]] </ins>(Expression Engineering) of [[20.109]], the introductory lab course for declared BE undergrad majors</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==Research==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==Research==</div></td></tr>  </table>

Andreat http://www.openwetware.org/index.php?title=User:Andreat&diff=95270&oldid=prev Andreat at 18:05, 25 January 2007 2007-01-25T18:05:17Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 18:05, 25 January 2007</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 10:</td> <td colspan="2" class="diff-lineno">Line 10:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>BA, Biological Sciences, University of Chicago, 2003</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>BA, Biological Sciences, University of Chicago, 2003</div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">===Currently..===</ins></div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">I am the TA for module 3 (Expression Engineering) of [[20.109]], the introductory lab course for declared BE undergrad majors</ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==Research==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==Research==</div></td></tr>  </table>

Andreat http://www.openwetware.org/index.php?title=User:Andreat&diff=92705&oldid=prev Andreat at 23:36, 2 January 2007 2007-01-02T23:36:49Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 23:36, 2 January 2007</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==Andrea Tentner==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==Andrea Tentner==</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>PhD Advisors:  Michael Yaffe and Douglas Lauffenburger</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>PhD Advisors:  <ins class="diffchange diffchange-inline">[http://web.mit.edu/be/people/yaffe.htm </ins>Michael Yaffe<ins class="diffchange diffchange-inline">] </ins>and <ins class="diffchange diffchange-inline">[http://web.mit.edu/be/people/lauffenburger.htm </ins>Douglas Lauffenburger<ins class="diffchange diffchange-inline">]</ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==Bio==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==Bio==</div></td></tr>  </table>

Andreat http://www.openwetware.org/index.php?title=User:Andreat&diff=92704&oldid=prev Andreat at 23:34, 2 January 2007 2007-01-02T23:34:35Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 23:34, 2 January 2007</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 14:</td> <td colspan="2" class="diff-lineno">Line 14:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>The cellular genome is continuously exposed to various sources of DNA damage.  Cells respond to DNA damage using extensive surveillance and repair mechanisms mediated largely by protein kinases and phosphatases.  In multi-cellular organisms, the accumulation of DNA damaged cells is avoided either through the activation of cell cycle checkpoints allowing for DNA repair or through the elimination of damaged cells by apoptosis.  To date, the study of the signaling mechanisms that govern the DNA damage response have focused on delineating the molecules involved in specific DNA damage response pathways.  However, to develop a comprehensive understanding of how the cell responds to DNA damage, dynamic measurements of signals within each specific pathway and across pathways, encompassing the entire relevant signal transduction network, is necessary. </div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>The cellular genome is continuously exposed to various sources of DNA damage.  Cells respond to DNA damage using extensive surveillance and repair mechanisms mediated largely by protein kinases and phosphatases.  In multi-cellular organisms, the accumulation of DNA damaged cells is avoided either through the activation of cell cycle checkpoints allowing for DNA repair or through the elimination of damaged cells by apoptosis.  To date, the study of the signaling mechanisms that govern the DNA damage response have focused on delineating the molecules involved in specific DNA damage response pathways.  However, to develop a comprehensive understanding of how the cell responds to DNA damage, dynamic measurements of signals within each specific pathway and across pathways, encompassing the entire relevant signal transduction network, is necessary. </div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>In this work we will focus on gaining insight into the relationship between the molecular signaling and cellular response to a therapeutically relevant DNA lesion, the DNA double strand break (DSB).</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>In this work we will focus on gaining insight into the relationship between the molecular signaling and cellular response to a therapeutically relevant DNA lesion, the DNA double strand break (DSB).</div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Our goal is to develop novel assays using In-cell Western and automated immunofluorescence (auto IF) technology that may be used to collect quantitative, dynamic, high throughput signaling information spanning the signaling pathways most relevant to DSB signaling.  This signaling data will be complemented by data representing a dense sampling of the components of the extended DNA damage network, to be monitored using high-throughput kinase assays and quantitative immunoblotting.   </div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Our goal is to develop novel assays using In-cell Western and automated immunofluorescence (auto IF) technology that may be used to collect quantitative, dynamic, high throughput signaling information spanning the signaling pathways most relevant to DSB signaling.  This signaling data will be complemented by data representing a dense sampling of the components of the extended DNA damage network, to be monitored using high-throughput kinase assays and quantitative immunoblotting.   </div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div> Taking advantage of this larger signaling data set, including cellular response measurements taken in parallel, our goal is to use data-driven modeling approaches to develop models of the DNA damage signal transduction network that will i) provide insight into the process by which cells decide their fate following induction of DSB, serving as a rich source for mechanistic hypothesis generation, and ii) be able to quantitatively predict apoptosis following novel perturbations to the signaling network.</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div> </div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>Taking advantage of this larger signaling data set, including cellular response measurements taken in parallel, our goal is to use data-driven modeling approaches to develop models of the DNA damage signal transduction network that will i) provide insight into the process by which cells decide their fate following induction of DSB, serving as a rich source for mechanistic hypothesis generation, and ii) be able to quantitatively predict apoptosis following novel perturbations to the signaling network.</div></td></tr>  </table>

Andreat http://www.openwetware.org/index.php?title=User:Andreat&diff=92703&oldid=prev Andreat at 23:33, 2 January 2007 2007-01-02T23:33:26Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 23:33, 2 January 2007</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==Andrea Tentner==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==Andrea Tentner==</div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">PhD Advisors:  Michael Yaffe and Douglas Lauffenburger</ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==Bio==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==Bio==</div></td></tr>  </table>

Andreat http://www.openwetware.org/index.php?title=User:Andreat&diff=92702&oldid=prev Andreat at 23:32, 2 January 2007 2007-01-02T23:32:26Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 23:32, 2 January 2007</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 8:</td> <td colspan="2" class="diff-lineno">Line 8:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>BA, Biological Sciences, University of Chicago, 2003</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>BA, Biological Sciences, University of Chicago, 2003</div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">==Research==</ins></div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">The cellular genome is continuously exposed to various sources of DNA damage.  Cells respond to DNA damage using extensive surveillance and repair mechanisms mediated largely by protein kinases and phosphatases.  In multi-cellular organisms, the accumulation of DNA damaged cells is avoided either through the activation of cell cycle checkpoints allowing for DNA repair or through the elimination of damaged cells by apoptosis.  To date, the study of the signaling mechanisms that govern the DNA damage response have focused on delineating the molecules involved in specific DNA damage response pathways.  However, to develop a comprehensive understanding of how the cell responds to DNA damage, dynamic measurements of signals within each specific pathway and across pathways, encompassing the entire relevant signal transduction network, is necessary. </ins></div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">In this work we will focus on gaining insight into the relationship between the molecular signaling and cellular response to a therapeutically relevant DNA lesion, the DNA double strand break (DSB).</ins></div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">Our goal is to develop novel assays using In-cell Western and automated immunofluorescence (auto IF) technology that may be used to collect quantitative, dynamic, high throughput signaling information spanning the signaling pathways most relevant to DSB signaling.  This signaling data will be complemented by data representing a dense sampling of the components of the extended DNA damage network, to be monitored using high-throughput kinase assays and quantitative immunoblotting.  </ins></div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"> Taking advantage of this larger signaling data set, including cellular response measurements taken in parallel, our goal is to use data-driven modeling approaches to develop models of the DNA damage signal transduction network that will i) provide insight into the process by which cells decide their fate following induction of DSB, serving as a rich source for mechanistic hypothesis generation, and ii) be able to quantitatively predict apoptosis following novel perturbations to the signaling network.</ins></div></td></tr>  </table>

Andreat http://www.openwetware.org/index.php?title=User:Andreat&diff=92695&oldid=prev Andreat at 22:32, 2 January 2007 2007-01-02T22:32:10Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 22:32, 2 January 2007</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del class="diffchange diffchange-inline">{{stub}}</del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">==Andrea Tentner==</ins></div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div> </div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">==Bio==</ins></div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div> </div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">PhD candidate, MIT, [http://web.mit.edu/be/index.htm Biological Engineering Department]</ins></div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div> </div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">MS, Biological Engineering, MIT 2006</ins></div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div> </div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">BA, Biological Sciences, University of Chicago, 2003</ins></div></td></tr>  </table>

Andreat http://www.openwetware.org/index.php?title=User:Andreat&diff=11884&oldid=prev Jason R. Kelly at 21:59, 23 June 2005 2005-06-23T21:59:54Z

<p></p> <p><b>New page</b></p><div>{{stub}}</div>

Jason R. Kelly