User:Blent/Seminar 07 fall: Difference between revisions

Revision as of 03:48, 26 September 2007

Toward Personalized Medicine in BMI-based Methodology: A case study of Carbamazepine and challenges in the future

case study #1: The First race-specific drug Bibil
- 活力藥師網番外篇
- Race in a Bottle, Jonathan Kahn. (Sci Am 2007 Aug)
- 科學人 2007 Sep
case study #2: CBZ-SJS
- 公視探索未知世界第二集: 解毒生命密碼-基因與藥物過敏
- 嚴重藥物過敏，可以預防 (科學人 2004 May)
Problem definition
Solution constructed by BI + MI
- Material and Method
  - Biomarkers discovery
ELSI and FDA guide line

make observations on collaboration of Bioinformatics (BI) and Medical Informatics (MI) through 1995 to 2007
comparative studies of BI and MI
- similarity of BI and MI
- difference of BI and MI
- collaboration of BI and MI
- market of BI and MI

BMI = BI + MI
- what BMI can do
  - Neuroinformatics (NI)
  - Cancer research (CR)
Personalized Medicine (PM)
- Motivation and case study
  - Stevens-Johnson syndrome and HLA-B 1502
- Methodology
  - MI
  - BI
- Products
- Problems remained

@@ Line 2: / Line 2: @@
 * Toward Personalized Medicine in BMI-based Methodology: A case study of [http://en.wikipedia.org/wiki/Carbamazepine Carbamazepine] and challenges in the future
 ==Outlines==
-* case study #1: The First race-specific drug '''Bibil''' and FDA guide lines
+* case study #1: The First race-specific drug '''Bibil'''
 ** [http://www.liverx.org/2007/09/05/藥瓶裡的種族問題/ 活力藥師網番外篇]
 ** [http://www.sciam.com/article.cfm?chanID=sa006&colID=1&articleID=B0FEC94D-E7F2-99DF-3CD8F25918B63A39 Race in a Bottle, Jonathan Kahn. (Sci Am 2007 Aug)]
@@ Line 9: / Line 9: @@
 ** [http://explore.pts.org.tw/p2.htm 公視 探索未知世界 第二集: 解毒生命密碼-基因與藥物過敏]
 ** [http://sa.ylib.com/news/newsshow.asp?FDocNo=438&CL=28 嚴重藥物過敏，可以預防 (科學人 2004 May)]
+* Problem definition
+* Solution constructed by BI + MI
+** Material and Method
+*** Biomarkers discovery
+* ELSI and FDA guide line
 ==Background==