User:Bryan Downie
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Contact Info
- Bryan Downie
- Max Planck of Experimental Medicine
- Hermen Rein Str 3
- 37075 Goettingen
- Germany
- Email me through OpenWetWare
I work in the MBNS Department at the Max Planck Institute of Experimental Medicine. I learned about OpenWetWare while web searching for protocols.
I'm currently examining the relationship between ion channels and tumor development, focusing specifically on the role of the potassium channel Eag1.
Education
- 2009, PhD of cell biology, University of Göttingen, Germany
- 2005, Diploma, University of Göttingen, Germany
- 2004, B.S. in Neurobiology, Univ of Washington, Seattle
Research interests
- Ion channels and cancer
- Nervous system vascularization
- Cellular signal transduction
Publications
- Downie BR, Sánchez A, Knötgen H, Contreras-Jurado C, Gymnopoulos M, Weber C, Stühmer W, and Pardo LA. Eag1 expression interferes with hypoxia homeostasis and induces angiogenesis in tumors. J Biol Chem. 2008 Dec 26;283(52):36234-40. DOI:10.1074/jbc.M801830200 |
- Weber C, de Queiroz FM, Downie BR, Suckow A, Stühmer W, and Pardo LA. Silencing the activity and proliferative properties of the human EagI Potassium Channel by RNA Interference. J Biol Chem. 2006 May 12;281(19):13030-13037. DOI:10.1074/jbc.M600883200 |
