To design bacteria that use specific miRNA signatures to target cancer cells.
During certain stages of growth, cancer cells exhibit unique miRNA signatures.<ref>Calin, George A., and Carlo M. Croce. "MicroRNA signatures in human cancers." Nature Reviews Cancer 6.11 (2006): 857-866.</ref>
Some organisms use miRNA to target and inhibit sections of bacterial DNA.<ref>Ma, Feng, et al. "The microRNA miR-29 controls innate and adaptive immune responses to intracellular bacterial infection by targeting interferon-[gamma]."Nature immunology 12.9 (2011): 861-869.</ref>