User:Damian Ekiert

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== Publications ==
== Publications ==
<blockquote>
<blockquote>
-
*Wang TT, Tan GS, Hai R, Pica N, Ngai L, '''Ekiert DC''', Wilson IA, García-Sastre A, Moran TM, Palese P. ''Vaccination with a synthetic peptide from the influenza virus hemagglutinin provides protection against distinct viral subtypes''. '''Proc Natl Acad Sci U S A'''. 2010 Nov 2;107(44):18979-84. PMID: 20956293
+
*Wang TT, Tan GS, Hai R, Pica N, Ngai L, '''Ekiert DC''', Wilson IA, García-Sastre A, Moran TM, Palese P.
-
*'''Xu R <nowiki>*</nowiki>''', '''Ekiert DC <nowiki>*</nowiki>''', Krause JC, Hai R, Crowe JE Jr, Wilson IA. ''Structural basis of preexisting immunity to the 2009 H1N1 pandemic influenza virus''. '''Science'''. 2010 Apr 16;328(5976):357-60. PMID: 20339031
+
:''Vaccination with a synthetic peptide from the influenza virus hemagglutinin provides protection against distinct viral subtypes''.
-
*'''Ekiert DC''', Bhabha G, Elsliger MA, Friesen RH, Jongeneelen M, Throsby M, Goudsmit J, Wilson IA. ''Antibody recognition of a highly conserved influenza virus epitope''. '''Science'''. 2009 Apr 10;324(5924):246-51. PMID: 19251591
+
:'''Proc Natl Acad Sci U S A'''. 2010 Nov 2;107(44):18979-84.
-
*Simon GC, Schonteich E, Wu CC, Piekny A, '''Ekiert D''', Yu X, Gould GW, Glotzer M, Prekeris R. ''Sequential Cyk-4 binding to ECT2 and FIP3 regulates cleavage furrow ingression and abscission during cytokinesis''. '''EMBO J'''. 2008 Jul 9;27(13):1791-803. PMID: 18511905
+
:PMID: 20956293
-
*Matic I, '''Ekiert D''', Radman M, Kohiyama M. ''Generation of DNA-free Escherichia coli cells by 2-aminopurine requires mismatch repair and nonmethylated DNA''. '''J Bacteriol'''. 2006 Jan;188(1):339-42. PMID: 16352851
+
 
-
*Strauss B, Kelly K, '''Ekiert D'''. ''Cytochrome oxidase deficiency protects Escherichia coli from cell death but not from filamentation due to thymine deficiency or DNA polymerase inactivation''. '''J Bacteriol'''. 2005 Apr;187(8):2827-35. PMID: 15805529
+
*'''Xu R <nowiki>*</nowiki>''', '''Ekiert DC <nowiki>*</nowiki>''', Krause JC, Hai R, Crowe JE Jr, Wilson IA.
-
*Strauss B, Kelly K, Dincman T, '''Ekiert D''', Biesieda T, Song R. ''Cell death in Escherichia coli dnaE(Ts) mutants incubated at a nonpermissive temperature is prevented by mutation in the cydA gene''. '''J Bacteriol'''. 2004 Apr;186(7):2147-55. PMID: 15028700  
+
:''Structural basis of preexisting immunity to the 2009 H1N1 pandemic influenza virus''.
 +
:'''Science'''. 2010 Apr 16;328(5976):357-60.
 +
:PMID: 20339031
 +
*'''Ekiert DC''', Bhabha G, Elsliger MA, Friesen RH, Jongeneelen M, Throsby M, Goudsmit J, Wilson IA.
 +
:''Antibody recognition of a highly conserved influenza virus epitope''.
 +
:'''Science'''. 2009 Apr 10;324(5924):246-51.
 +
:PMID: 19251591
 +
*Simon GC, Schonteich E, Wu CC, Piekny A, '''Ekiert D''', Yu X, Gould GW, Glotzer M, Prekeris R.
 +
:''Sequential Cyk-4 binding to ECT2 and FIP3 regulates cleavage furrow ingression and abscission during cytokinesis''.
 +
:'''EMBO J'''. 2008 Jul 9;27(13):1791-803.
 +
:PMID: 18511905
 +
*Matic I, '''Ekiert D''', Radman M, Kohiyama M.
 +
:''Generation of DNA-free Escherichia coli cells by 2-aminopurine requires mismatch repair and nonmethylated DNA''.
 +
:'''J Bacteriol'''. 2006 Jan;188(1):339-42.
 +
:PMID: 16352851
 +
*Strauss B, Kelly K, '''Ekiert D'''.
 +
:''Cytochrome oxidase deficiency protects Escherichia coli from cell death but not from filamentation due to thymine deficiency or DNA polymerase inactivation''.
 +
:'''J Bacteriol'''. 2005 Apr;187(8):2827-35.
 +
:PMID: 15805529
 +
*Strauss B, Kelly K, Dincman T, '''Ekiert D''', Biesieda T, Song R.
 +
:''Cell death in Escherichia coli dnaE(Ts) mutants incubated at a nonpermissive temperature is prevented by mutation in the cydA gene''.
 +
:'''J Bacteriol'''. 2004 Apr;186(7):2147-55.
 +
:PMID: 15028700  
</blockquote>
</blockquote>

Revision as of 03:15, 1 December 2010

Damian C. Ekiert

PhD Candidate
Department of Molecular Biology and
The Skaggs Institute for Chemical Biology
The Scripps Research Institute
10550 N. Torrey Pines Rd.
BCC-206 La Jolla, CA 92037
858-784-2941
dcekiert at scripps dot edu

I am a graduate student in the Wilson Lab at The Scripps Research Institute.


Contents

Research Interests

  • Neutralization of influenza viruses by antibodies
  • Rational vaccine design guided by broadly neutralizing antibodies
  • Diversity of antibody structure and function

Education

Past Lab Work

  • 2007-2011: Prof. Ian A. Wilson Lab, thesis, structural characterization of broadly neutralizing antibodies against the influenza A virus.
  • 2006-2007: Prof. Carlos Barbas Lab, graduate rotation, directed evolution of site specific recombinases for genome engineering and gene therapy.
  • 2005-2006: Prof. Michael Glotzer Lab (gap year) working on cytokinesis in mammalian cells.
  • 2003-2004: Prof. Miroslav Radman (Université Paris Descartes) and Prof. Masamichi Kohiyama (Université Pierre et Marie Curie) groups during year abroad in Paris, working on mismatch-stimulated killing and the localization of replication forks in E. coli.
  • 2003-2005: Prof. Bernard Strauss Lab (University of Chicago), undergraduate honors thesis, investigating the coordination of DNA replication and cell division in E. coli.

Publications

  • Wang TT, Tan GS, Hai R, Pica N, Ngai L, Ekiert DC, Wilson IA, García-Sastre A, Moran TM, Palese P.
Vaccination with a synthetic peptide from the influenza virus hemagglutinin provides protection against distinct viral subtypes.
Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):18979-84.
PMID: 20956293
  • Xu R *, Ekiert DC *, Krause JC, Hai R, Crowe JE Jr, Wilson IA.
Structural basis of preexisting immunity to the 2009 H1N1 pandemic influenza virus.
Science. 2010 Apr 16;328(5976):357-60.
PMID: 20339031
  • Ekiert DC, Bhabha G, Elsliger MA, Friesen RH, Jongeneelen M, Throsby M, Goudsmit J, Wilson IA.
Antibody recognition of a highly conserved influenza virus epitope.
Science. 2009 Apr 10;324(5924):246-51.
PMID: 19251591
  • Simon GC, Schonteich E, Wu CC, Piekny A, Ekiert D, Yu X, Gould GW, Glotzer M, Prekeris R.
Sequential Cyk-4 binding to ECT2 and FIP3 regulates cleavage furrow ingression and abscission during cytokinesis.
EMBO J. 2008 Jul 9;27(13):1791-803.
PMID: 18511905
  • Matic I, Ekiert D, Radman M, Kohiyama M.
Generation of DNA-free Escherichia coli cells by 2-aminopurine requires mismatch repair and nonmethylated DNA.
J Bacteriol. 2006 Jan;188(1):339-42.
PMID: 16352851
  • Strauss B, Kelly K, Ekiert D.
Cytochrome oxidase deficiency protects Escherichia coli from cell death but not from filamentation due to thymine deficiency or DNA polymerase inactivation.
J Bacteriol. 2005 Apr;187(8):2827-35.
PMID: 15805529
  • Strauss B, Kelly K, Dincman T, Ekiert D, Biesieda T, Song R.
Cell death in Escherichia coli dnaE(Ts) mutants incubated at a nonpermissive temperature is prevented by mutation in the cydA gene.
J Bacteriol. 2004 Apr;186(7):2147-55.
PMID: 15028700
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