User:Damian Ekiert

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*Wang TT, Tan GS, Hai R, Pica N, Ngai L, '''Ekiert DC''', Wilson IA, García-Sastre A, Moran TM, Palese P.
*Wang TT, Tan GS, Hai R, Pica N, Ngai L, '''Ekiert DC''', Wilson IA, García-Sastre A, Moran TM, Palese P.
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:[http://www.ncbi.nlm.nih.gov/pubmed/20956293|''Vaccination with a synthetic peptide from the influenza virus hemagglutinin provides protection against distinct viral subtypes''.]
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:[http://www.ncbi.nlm.nih.gov/pubmed/20956293 | ''Vaccination with a synthetic peptide from the influenza virus hemagglutinin provides protection against distinct viral subtypes''.]
:'''Proc Natl Acad Sci U S A'''. 2010 Nov 2;107(44):18979-84.
:'''Proc Natl Acad Sci U S A'''. 2010 Nov 2;107(44):18979-84.
:PMID: 20956293
:PMID: 20956293

Revision as of 21:01, 1 December 2010

Damian C. Ekiert

PhD Candidate
Department of Molecular Biology and
The Skaggs Institute for Chemical Biology
The Scripps Research Institute
10550 N. Torrey Pines Rd.
BCC-206 La Jolla, CA 92037
858-784-2941
dcekiert at scripps dot edu

I am a graduate student in the Wilson Lab at The Scripps Research Institute.


Contents

Research Interests

  • Neutralization of influenza viruses by antibodies
  • Rational vaccine design guided by broadly neutralizing antibodies
  • Diversity of antibody structure and function

Education

Research Experience

  • 2007-2011: Prof. Ian A. Wilson Lab, thesis, structural characterization of broadly neutralizing antibodies against the influenza A virus.
  • 2006-2007: Prof. Carlos Barbas Lab, graduate rotation, directed evolution of site specific recombinases for genome engineering and gene therapy.
  • 2005-2006: Prof. Michael Glotzer Lab (gap year) working on cytokinesis in mammalian cells.
  • 2003-2004: Prof. Miroslav Radman (Université Paris Descartes) and Prof. Masamichi Kohiyama (Université Pierre et Marie Curie) groups during year abroad in Paris, working on mismatch-stimulated killing and the localization of replication forks in E. coli.
  • 2003-2005: Prof. Bernard Strauss Lab (University of Chicago), undergraduate honors thesis, investigating the coordination of DNA replication and cell division in E. coli.

Publications

  • Wang TT, Tan GS, Hai R, Pica N, Ngai L, Ekiert DC, Wilson IA, García-Sastre A, Moran TM, Palese P.
| Vaccination with a synthetic peptide from the influenza virus hemagglutinin provides protection against distinct viral subtypes.
Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):18979-84.
PMID: 20956293
  • Xu R *, Ekiert DC *, Krause JC, Hai R, Crowe JE Jr, Wilson IA.
Structural basis of preexisting immunity to the 2009 H1N1 pandemic influenza virus.
Science. 2010 Apr 16;328(5976):357-60.
PMID: 20339031
  • Ekiert DC, Bhabha G, Elsliger MA, Friesen RH, Jongeneelen M, Throsby M, Goudsmit J, Wilson IA.
Antibody recognition of a highly conserved influenza virus epitope.
Science. 2009 Apr 10;324(5924):246-51.
PMID: 19251591
  • Simon GC, Schonteich E, Wu CC, Piekny A, Ekiert D, Yu X, Gould GW, Glotzer M, Prekeris R.
Sequential Cyk-4 binding to ECT2 and FIP3 regulates cleavage furrow ingression and abscission during cytokinesis.
EMBO J. 2008 Jul 9;27(13):1791-803.
PMID: 18511905
  • Matic I, Ekiert D, Radman M, Kohiyama M.
Generation of DNA-free Escherichia coli cells by 2-aminopurine requires mismatch repair and nonmethylated DNA.
J Bacteriol. 2006 Jan;188(1):339-42.
PMID: 16352851
  • Strauss B, Kelly K, Ekiert D.
Cytochrome oxidase deficiency protects Escherichia coli from cell death but not from filamentation due to thymine deficiency or DNA polymerase inactivation.
J Bacteriol. 2005 Apr;187(8):2827-35.
PMID: 15805529
  • Strauss B, Kelly K, Dincman T, Ekiert D, Biesieda T, Song R.
Cell death in Escherichia coli dnaE(Ts) mutants incubated at a nonpermissive temperature is prevented by mutation in the cydA gene.
J Bacteriol. 2004 Apr;186(7):2147-55.
PMID: 15028700
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