User:Dannielle Ryman

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Lab Overview

The mission of the Peyton lab is to learn how a variety of different cell types are able to process information from biochemical and biophysical cues from the ECM and make decisions about migration and phenotype. To do this, our lab uses both 2D and 3D biomaterial model systems, which can be engineered from the ground-up to instruct cells via both biochemical and biophysical signaling pathways. This broader mission will be focused onto different research avenues with applications toward: cardiovascular disease, where tissue homeostasis is normally maintained in a mechanically dynamic ECM; stem-cell therapeutics, where rational scaffold design may be the key to directing appropriate progenitor cell migration and differentiation for tissue regeneration; and cancer, where disruptions in the local ECM microenvironment may cause drastic changes in individual cell motility and phenotype.

Memberships/Affiliates

2011, CBI [3]

The Materials Research Science and Engineering Center

The Chemistry-Biology Interface

The Institute for Cellular Engineering