User:Davd A Hiller
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Contact Info
- David A Hiller
- Yale University
- New Haven, CT, USA
- Email me through OpenWetWare
Education
- 2005, PhD, University of California at Santa Barbara
- 2000, BS, California Institute of Technology
Research interests
- Enzymology
- Nucleic Acids
- Drug Design
Publications
- Hiller DA, Zhong M, Singh V, and Strobel SA. Transition states of uncatalyzed hydrolysis and aminolysis reactions of a ribosomal P-site substrate determined by kinetic isotope effects. Biochemistry. 2010 May 11;49(18):3868-78. DOI:10.1021/bi901458x |
- Hiller DA and Perona JJ. Positively charged C-terminal subdomains of EcoRV endonuclease: contributions to DNA binding, bending, and cleavage. Biochemistry. 2006 Sep 26;45(38):11453-63. DOI:10.1021/bi0606400 |
- Hiller DA, Rodriguez AM, and Perona JJ. Non-cognate enzyme-DNA complex: structural and kinetic analysis of EcoRV endonuclease bound to the EcoRI recognition site GAATTC. J Mol Biol. 2005 Nov 18;354(1):121-36. DOI:10.1016/j.jmb.2005.09.046 |
- Hiller DA, Fogg JM, Martin AM, Beechem JM, Reich NO, and Perona JJ. Simultaneous DNA binding and bending by EcoRV endonuclease observed by real-time fluorescence. Biochemistry. 2003 Dec 16;42(49):14375-85. DOI:10.1021/bi035520w |