User:DavidDrubin - Revision history

DavidDrubin: /* Interests & Hobbies */

DavidDrubin — Thu, 10 Apr 2008 19:51:30 GMT

Interests & Hobbies

←Older revision		Revision as of 19:51, 10 April 2008
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	G. Clawson, D. Drubin, M. McLaughlin-Drubin, C. Meyers. “Compositions and methods for inhibiting abnormal cell growth”, patent pending.		G. Clawson, D. Drubin, M. McLaughlin-Drubin, C. Meyers. “Compositions and methods for inhibiting abnormal cell growth”, patent pending.
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-	~~== Interests & Hobbies ==~~

DavidDrubin: /* Publications */

DavidDrubin — Thu, 10 Apr 2008 19:51:13 GMT

Publications

←Older revision		Revision as of 19:51, 10 April 2008
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	Drubin, DA and Clawson, GA (2004). Spontaneous transformation of an immortalized hepatocyte cell line: potential role of a nuclear protease. ''Cancer Letters'' 213: 39-48.		Drubin, DA and Clawson, GA (2004). Spontaneous transformation of an immortalized hepatocyte cell line: potential role of a nuclear protease. ''Cancer Letters'' 213: 39-48.

-	G. Clawson, D. Drubin, M. McLaughlin-Drubin, C. Meyers. ~~“A Nuclear Protease Inhibitor as a Topical Therapeutic~~ for ~~Cervical Dysplasias”~~, patent pending.	+	G. Clawson, D. Drubin, M. McLaughlin-Drubin, C. Meyers. “Compositions and methods for inhibiting abnormal cell growth”, patent pending.

	== Interests & Hobbies ==		== Interests & Hobbies ==

DavidDrubin: /* = Publications */

DavidDrubin — Fri, 21 Sep 2007 14:14:08 GMT

= Publications

←Older revision		Revision as of 14:14, 21 September 2007
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	We are pursuing the design and construction of a mammalian cell-based sensor-memory device. Such a device will be able to report whether specific events occur in a cell or whether certain compounds are present in the cell's environment, and then store this information in itself and in all the cell's progeny. Furthermore, such a system could also be designed to report on quantity of a particular stimulus. A key feature of such a system will be its portability to various environmental stimuli or specific cellular events, and will not be limited to very specific chemical inductions. We are also interested in the applied uses of a memory device in more functionally creative and complex cellular circuits.		We are pursuing the design and construction of a mammalian cell-based sensor-memory device. Such a device will be able to report whether specific events occur in a cell or whether certain compounds are present in the cell's environment, and then store this information in itself and in all the cell's progeny. Furthermore, such a system could also be designed to report on quantity of a particular stimulus. A key feature of such a system will be its portability to various environmental stimuli or specific cellular events, and will not be limited to very specific chemical inductions. We are also interested in the applied uses of a memory device in more functionally creative and complex cellular circuits.

-	== Publications =	+	= Publications =
	Ajo-Franklin CM, Drubin DA, Eskin JA, Gee EPS, Landgraf D, Phillips I, and Silver PA. Rational design of memory in eukaryotic cells. ''Genes Dev '' 21: 2271-2276. *authors contributed equally to this work.		Ajo-Franklin CM, Drubin DA, Eskin JA, Gee EPS, Landgraf D, Phillips I, and Silver PA. Rational design of memory in eukaryotic cells. ''Genes Dev '' 21: 2271-2276. *authors contributed equally to this work.

DavidDrubin: /* Publications */

DavidDrubin — Fri, 21 Sep 2007 13:21:30 GMT

Publications

←Older revision		Revision as of 13:21, 21 September 2007
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	We are pursuing the design and construction of a mammalian cell-based sensor-memory device. Such a device will be able to report whether specific events occur in a cell or whether certain compounds are present in the cell's environment, and then store this information in itself and in all the cell's progeny. Furthermore, such a system could also be designed to report on quantity of a particular stimulus. A key feature of such a system will be its portability to various environmental stimuli or specific cellular events, and will not be limited to very specific chemical inductions. We are also interested in the applied uses of a memory device in more functionally creative and complex cellular circuits.		We are pursuing the design and construction of a mammalian cell-based sensor-memory device. Such a device will be able to report whether specific events occur in a cell or whether certain compounds are present in the cell's environment, and then store this information in itself and in all the cell's progeny. Furthermore, such a system could also be designed to report on quantity of a particular stimulus. A key feature of such a system will be its portability to various environmental stimuli or specific cellular events, and will not be limited to very specific chemical inductions. We are also interested in the applied uses of a memory device in more functionally creative and complex cellular circuits.

-	== Publications ==	+	== Publications =
-	Ajo-Franklin CM, Drubin DA, Eskin JA, Gee EPS, Landgraf D, Phillips I, and Silver PA. Rational design of memory in eukaryotic cells. "Genes Dev" 21: 2271-2276. *authors contributed equally to this work.	+	Ajo-Franklin CM, Drubin DA, Eskin JA, Gee EPS, Landgraf D, Phillips I, and Silver PA. Rational design of memory in eukaryotic cells. ''Genes Dev '' 21: 2271-2276. *authors contributed equally to this work.

	Drubin, DA, Way, JC, and Silver, PA. (2007). Designing biological systems. ''Genes Dev '' 21(3): 242-254.		Drubin, DA, Way, JC, and Silver, PA. (2007). Designing biological systems. ''Genes Dev '' 21(3): 242-254.

DavidDrubin: /* Publications */

DavidDrubin — Fri, 21 Sep 2007 13:21:08 GMT

Publications

←Older revision		Revision as of 13:21, 21 September 2007
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	== Publications ==		== Publications ==
-	Ajo-Franklin CM, Drubin DA, Eskin JA, Gee EPS, Landgraf D, Phillips I, and Silver PA. Rational design of memory in eukaryotic cells. ~~''Manuscript accepted at~~ Genes ~~and Development''~~. *authors contributed equally to this work.	+	Ajo-Franklin CM, Drubin DA, Eskin JA, Gee EPS, Landgraf D, Phillips I, and Silver PA. Rational design of memory in eukaryotic cells. "Genes Dev" 21: 2271-2276. *authors contributed equally to this work.

	Drubin, DA, Way, JC, and Silver, PA. (2007). Designing biological systems. ''Genes Dev '' 21(3): 242-254.		Drubin, DA, Way, JC, and Silver, PA. (2007). Designing biological systems. ''Genes Dev '' 21(3): 242-254.

DavidDrubin: /* Research Interests */

DavidDrubin — Thu, 02 Aug 2007 15:29:58 GMT

Research Interests

←Older revision		Revision as of 15:29, 2 August 2007
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	== Research Interests ==		== Research Interests ==

-	We are pursuing the design and construction of a mammalian cell-based sensor-memory device. Such a device will be able to report whether specific events occur in a cell or whether certain compounds are present in the cell's environment, and then store this information in itself and in all the cell's progeny. Furthermore, such a system could also be designed to report on quantity of a particular stimulus. A key feature of such a system will be its portability to various environmental stimuli or specific cellular events, and will not be limited to very specific chemical inductions.	+	We are pursuing the design and construction of a mammalian cell-based sensor-memory device. Such a device will be able to report whether specific events occur in a cell or whether certain compounds are present in the cell's environment, and then store this information in itself and in all the cell's progeny. Furthermore, such a system could also be designed to report on quantity of a particular stimulus. A key feature of such a system will be its portability to various environmental stimuli or specific cellular events, and will not be limited to very specific chemical inductions. We are also interested in the applied uses of a memory device in more functionally creative and complex cellular circuits.

	== Publications ==		== Publications ==

DavidDrubin: /* Publications */

DavidDrubin — Thu, 02 Aug 2007 15:27:30 GMT

Publications

←Older revision		Revision as of 15:27, 2 August 2007
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	== Publications ==		== Publications ==
-	Ajo-Franklin CM, Drubin DA, Eskin JA, Gee EPS, Landgraf D, Phillips I, and Silver PA. Rational design of memory in eukaryotic cells. Manuscript accepted at Genes and Development. *authors contributed equally to this work.	+	Ajo-Franklin CM, Drubin DA, Eskin JA, Gee EPS, Landgraf D, Phillips I, and Silver PA. Rational design of memory in eukaryotic cells. ''Manuscript accepted at Genes and Development''. *authors contributed equally to this work.

	Drubin, DA, Way, JC, and Silver, PA. (2007). Designing biological systems. ''Genes Dev '' 21(3): 242-254.		Drubin, DA, Way, JC, and Silver, PA. (2007). Designing biological systems. ''Genes Dev '' 21(3): 242-254.

DavidDrubin: /* Publications */

DavidDrubin — Thu, 02 Aug 2007 15:26:48 GMT

Publications

←Older revision		Revision as of 15:26, 2 August 2007
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	== Publications ==		== Publications ==
-	Ajo-Franklin, CM, Drubin, DA, Eskin, JA, Gee~~, E~~, Landgraf, D, Phillips, I, and Silver, PA. Rational design of memory in eukaryotic cells. Manuscript accepted at Genes and Development. *authors contributed equally to this work.	+	Ajo-Franklin CM, Drubin DA, Eskin JA, Gee EPS, Landgraf D, Phillips I, and Silver PA. Rational design of memory in eukaryotic cells. Manuscript accepted at Genes and Development. *authors contributed equally to this work.

	Drubin, DA, Way, JC, and Silver, PA. (2007). Designing biological systems. ''Genes Dev '' 21(3): 242-254.		Drubin, DA, Way, JC, and Silver, PA. (2007). Designing biological systems. ''Genes Dev '' 21(3): 242-254.

DavidDrubin: /* Publications */

DavidDrubin — Thu, 02 Aug 2007 15:25:28 GMT

Publications

←Older revision		Revision as of 15:25, 2 August 2007
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	== Publications ==		== Publications ==
		+	Ajo-Franklin, CM, Drubin, DA, Eskin, JA, Gee, E, Landgraf, D, Phillips, I, and Silver, PA. Rational design of memory in eukaryotic cells. Manuscript accepted at Genes and Development. *authors contributed equally to this work.
		+
	Drubin, DA, Way, JC, and Silver, PA. (2007). Designing biological systems. ''Genes Dev '' 21(3): 242-254.		Drubin, DA, Way, JC, and Silver, PA. (2007). Designing biological systems. ''Genes Dev '' 21(3): 242-254.

DavidDrubin: /* Biographical Info */

DavidDrubin — Wed, 02 May 2007 14:50:54 GMT

Biographical Info

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	david_drubin at hms dot harvard dot edu		david_drubin at hms dot harvard dot edu

-	-~~3rd~~ year Postdoctoral Research Fellow	+	-4th year Postdoctoral Research Fellow

	-Ph.D. Integrative Biosciences-Molecular Medicine, Penn State University College of Medicine, 2004		-Ph.D. Integrative Biosciences-Molecular Medicine, Penn State University College of Medicine, 2004