User:Dileep D. Monie

Contact Info

• Dileep D. Monie
• Johns Hopkins University
• Baltimore, MD, USA
• Email me through OpenWetWare

I work in the Wilmer Eye Institute at the JHU School of Medicine. I learned about OpenWetWare from the 24C3 Endy lecture, and I've joined because I am interested in contributing to the BBF Technical Standards.

Research Interests

1. Synthetic Biology
   1. Standards - Establishing standards for biological parts to ensure interoperability and allow for construction of complex systems
   2. Biocircuits - Implementing wetware abstraction layers to allow creation of devices for cellular computation and communications
   3. Epigenetics - Manipulating chromatin structures with histone and DNA modifications as a form of biological software programming
   4. Delivery Systems - Making viruses or other vectors for targeted delivery of DNA parts into an established host genome
2. Bioengineering
   1. Immunology - Defining the theoretical framework and designing components for an artificial immune system
   2. Drug Discovery - Designing cell reporter systems to detect biomolecule interactions and perturbations in signal transduction
   3. Astrobiology - Engineering energy pathways and lifeforms sustainable in extreme environments
   4. Biocomputing - Integrating logic biocircuits on a very large scale in single cell and multicellular systems
3. Biosecurity and Biosafety
   1. Policy - Balancing the needs of an open hacker community with access restrictions
   2. Testing and Certification - Establishing an "Underwriters Laboratories" for developing standards and test procedures for biosafety
   3. Countermeasures - Designing fail-safe mechanisms to mitigate potential synthetic biology abuses

BBF Contributions

• BBF Technical Standards Promoter Measurement Test

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