User:Dileep D. Monie: Difference between revisions
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==Contact Info== | ==Contact Info== | ||
[[Image: | [[Image:Dileep.jpg|thumb|right|Dileep D. Monie]] | ||
*Dileep D. Monie | *Dileep D. Monie | ||
*[http:// | **[http://scholar.harvard.edu/dmonie Teaching Fellow, Harvard University] | ||
* | **[https://www.broadinstitute.org/directory/?usersearch=Dileep+Monie&usearch=Search Associated Researcher, Broad Institute of MIT and Harvard] | ||
*[ | **[[BUGSS|Director & Secretary, Baltimore Under Ground Science Space (BUGSS)]] | ||
I learned about [[OpenWetWare]] from [http://events.ccc.de/congress/2007/Fahrplan/events/2329.en.html Drew Endy's 24C3 lecture], and I've joined because I am interested in making biology easier to engineer. Please feel free to [[Special:Emailuser/Dileep D. Monie|contact me on OWW]] or [http://www.linkedin.com/in/dmonie connect on LinkedIn]. | |||
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==Research Interests== | ==Research Interests== | ||
# | # Synthetic Biology | ||
## | ## Standards - Establishing standards for biological parts to ensure interoperability and allow for construction of complex systems | ||
## Biocircuits - | ## Biocircuits - Implementing wetware abstraction layers to allow creation of devices for cellular computation and communications | ||
## | ## Epigenetics - Manipulating chromatin structures with histone and DNA modifications as a form of biological software programming | ||
# | ## Delivery Systems - Making viruses or other vectors for targeted delivery of DNA parts into an established host genome | ||
# Bioengineering | |||
## Immunology - Defining the theoretical framework and designing components for an artificial immune system | ## Immunology - Defining the theoretical framework and designing components for an artificial immune system | ||
## Astrobiology - Engineering | ## Drug Discovery - Designing cell reporter systems to detect biomolecule interactions and perturbations in signal transduction | ||
## Biocomputing - | ## Astrobiology - Engineering energy pathways and lifeforms sustainable in extreme environments | ||
# Biosecurity | ## Biocomputing - Integrating logic biocircuits on a very large scale in single cell and multicellular systems | ||
# Biosecurity and Biosafety | |||
## Policy - Balancing the needs of an open hacker community with access restrictions | ## Policy - Balancing the needs of an open hacker community with access restrictions | ||
## Countermeasures - | ## Testing and Certification - Establishing an "Underwriters Laboratories" for developing standards and test procedures for biosafety | ||
## Countermeasures - Designing fail-safe mechanisms to mitigate potential synthetic biology abuses | |||
--> | |||
== | ==BBF Contributions== | ||
*[[The_BioBricks_Foundation:Standards/Technical | *[[The_BioBricks_Foundation:Standards/Technical|Technical Standards]] | ||
*[[/Notebook/BBF_Standards_Measurement|Promoter Measurement Test]] | |||
==OWW Brain Dump== | |||
*[[/Notebook|Notebook]] | |||
*[[/Recipes|Recipes]] | |||
*[http://openwetware.org/index.php?title=Special%3ALog&type=upload&user=Dileep+D.+Monie Upload log] | |||
==Publications== | ==Publications== | ||
<biblio> | <biblio> | ||
#Paper1 pmid= | #Paper1 pmid=10201994 | ||
#Paper2 pmid= | #Paper2 pmid=10441117 | ||
#Paper3 pmid=19298678 | |||
#Book1 isbn= | #Paper4 pmid=21212284 | ||
#Book1 isbn=9780781764964 | |||
// Contributed section on "Pulmonary Hypertension" (pp. 148-9) | |||
</biblio> | </biblio> | ||
Revision as of 14:58, 29 September 2015
Contact Info
- Dileep D. Monie
I learned about OpenWetWare from Drew Endy's 24C3 lecture, and I've joined because I am interested in making biology easier to engineer. Please feel free to contact me on OWW or connect on LinkedIn.
BBF Contributions
OWW Brain Dump
Publications
- Monday SR, Vath GM, Ferens WA, Deobald C, Rago JV, Gahr PJ, Monie DD, Iandolo JJ, Chapes SK, Davis WC, Ohlendorf DH, Schlievert PM, and Bohach GA. Unique superantigen activity of staphylococcal exfoliative toxins. J Immunol. 1999 Apr 15;162(8):4550-9.
- Vath GM, Earhart CA, Monie DD, Iandolo JJ, Schlievert PM, and Ohlendorf DH. The crystal structure of exfoliative toxin B: a superantigen with enzymatic activity. Biochemistry. 1999 Aug 10;38(32):10239-46. DOI:10.1021/bi990721e |
- Kelly JR, Rubin AJ, Davis JH, Ajo-Franklin CM, Cumbers J, Czar MJ, de Mora K, Glieberman AL, Monie DD, and Endy D. Measuring the activity of BioBrick promoters using an in vivo reference standard. J Biol Eng. 2009 Mar 20;3:4. DOI:10.1186/1754-1611-3-4 |
- Oh U, McCormick MJ, Datta D, Turner RV, Bobb K, Monie DD, Sliskovic DR, Tanaka Y, Zhang J, Meshulam J, and Jacobson S. Inhibition of immune activation by a novel nuclear factor-kappa B inhibitor in HTLV-I-associated neurologic disease. Blood. 2011 Mar 24;117(12):3363-9. DOI:10.1182/blood-2010-10-306571 |
- ISBN:9780781764964
Contributed section on "Pulmonary Hypertension" (pp. 148-9)