User:Tkadm30/Notebook/Aripiprazole: Difference between revisions
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* [https://www.ncbi.nlm.nih.gov/pubmed/25735995 Dopamine supersensitivity psychosis and dopamine partial agonist: a retrospective survey of failure of switching to aripiprazole in schizophrenia.] | * [https://www.ncbi.nlm.nih.gov/pubmed/25735995 Dopamine supersensitivity psychosis and dopamine partial agonist: a retrospective survey of failure of switching to aripiprazole in schizophrenia.] | ||
* Akathisia | * Akathisia | ||
* Insomnia | |||
===Notes=== | ===Notes=== | ||
Revision as of 02:11, 30 April 2017
Functional selectivity of aripiprazole at D2 receptors
- Aripiprazole has functionally selective actions at dopamine D2 receptor-mediated signaling pathways.
- Protective effect of aripiprazole against glutamate cytotoxicity in dopaminergic neurons of rat mesencephalic cultures.
- Antagonism of the adenosine A2A receptor attenuates akathisia-like behavior induced with MP-10 or aripiprazole in a novel non-human primate model.
- Repeated aripiprazole treatment causes dopamine D2 receptor up-regulation and dopamine supersensitivity in young rats.
- Unique Effects of Acute Aripiprazole Treatment on the Dopamine D2 Receptor Downstream cAMP-PKA and Akt-GSK3β Signalling Pathways in Rats
- Chronic administration of aripiprazole activates GSK3β-dependent signalling pathways, and up-regulates GABAA receptor expression and CREB1 activity in rats
Corticostriatal glutamatergic transmission
- Heteromeric adenosine-CB1 activation increase functional connectivity at dopamine D2 receptors?
- Effects of Aripiprazole and Haloperidol on Fos-like Immunoreactivity in the Prefrontal Cortex
Side effects
- Worsened hypertension control induced by aripiprazole
- Dopamine supersensitivity psychosis and dopamine partial agonist: a retrospective survey of failure of switching to aripiprazole in schizophrenia.
- Akathisia
- Insomnia
Notes
- Is Aripiprazole a selective FAAH inhibitor?
