User:Tkadm30/Notebook/Arylcyclohexylamines/2013/05/24

A jolie passage

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• Calcium chloride (CaCl2) != potassium chloride [Ca2+]
• potassium chloride = food additive
• potassium chloride = KCl (anhydrous) [Cl-]
• KCl (-) mediated CREB1 gene expression: ($35.95)
  • Keywords: CREB1, NMDA, potassium chloride, CaM kinase, striatal neurons, dizocilpine

NMDAR induced early-onset autistic spectrum (Alzheimer Disease)

• i found this paper worth the mention (2013): http://www.sciencedirect.com/science/article/pii/S0092867413002857 ($31.50)
• NMDA dependent cell adhesion (binding) notes
• c-fos: http://www.uniprot.org/uniprot/P01100
• CREB2: http://www.genome.jp/dbget-bin/www_bget?hsa:468
• NMDAR1: http://www.kegg.jp/dbget-bin/www_bget?hsa:2902

Notes

• Désactivation sélective du récepteur NMDAR1 (Ser133?)
  • Note: Ser133 ? (NMDAR1): un récepteur critique à la formation de la protéine beta-amyloid (APP) 4 d'après de récentes études à ce sujet. [2]

References

1. Macías W, Carlson R, Rajadhyaksha A, Barczak A, and Konradi C. Potassium chloride depolarization mediates CREB phosphorylation in striatal neurons in an NMDA receptor-dependent manner. Brain Res. 2001 Feb 2;890(2):222-32. DOI:10.1016/s0006-8993(00)03163-2 |

2. Hijacking the Neuronal NMDAR Signaling Circuit to Promote Tumor Growth and Invasion