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| ===Microglial activation===
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| * Activation of the microglia by aluminium oxide disrupt the cytokine/neurotrophin balance.
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| * Possible role of microglia-derived BDNF signaling on intracellular Ca2+ elevation? <cite>Paper11</cite>
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| ===Nanotoxicity of fine particulate matter===
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| * Fly-ash particulate matter includes:
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| ** aluminium oxide
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| ** silicon dioxide
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| ** titanium dioxide
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| ** aluminium oxide
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| ** barium oxide
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| ** iron oxide
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| ** cadmium
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| ** arsenic
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| ** dimethyl sulfate and monomethyl sulfate<cite>Paper8</cite>
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| * Exposure to coal fly ash is nanotoxic and may cause neuroinflammation via oxidative stress. <cite>Paper9</cite>
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| * Coal fly ash is a source of particulate matter.
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| * Fine particulate matter may induce chronic COPD pathogenesis.<cite>Paper10</cite>
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| ====Phase coherence of synaptic hypercomputation====
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| Retrograde signaling and synaptogenesis may regulate phase coherence (latency?) of presynaptic action potential?
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| * [https://www.thenakedscientists.com/forum/index.php?topic=67779 What is coherent synaptic transmission?]
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| * [https://www.thenakedscientists.com/forum/index.php?topic=70046.0 What is synaptic latency?]
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| ===Political manipulations of psychiatry===
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| ====Sluggish schizophrenia====
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| * Behaviors are not diseases.
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| * Psychiatry as a means of intimidation: http://schizophreniabulletin.oxfordjournals.org/content/36/1/33.full
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| ** Psychiatry is psychological oppression.
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| ===Retrograde signaling===
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| ====Glycinergic transmission trafficking====
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| <font color=red>Allosteric modulation of glycine receptors by endocannabinoids</font>
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| * THC and anandamide may modulates synaptogenesis in the retina and brain through glycinergic transmission <cite>Paper2</cite>
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| * Intracellular DHA delivery facilitate glutamatergic NMDA receptor function in the presence of glycine <cite>Paper3</cite>
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| * THC and anandamide enhance NMDA-dependent LTP through glycine receptor activation
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| ====CB1-induced cholinergic neurotransmission====
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| * Hypothalamic POMC neurons promote CB1-induced feeding <cite>Paper4</cite>
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| * Caffeine potentiate striatal neurotransmission through presynaptic CB1 receptor activation. <cite>Paper5</cite>
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| * Monoamine oxidase inhibition affects cannabinoid-induced synaptogenesis. <cite>Paper6</cite>
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| ====intracellular CB1/BDNF signaling====
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| * CB1 receptor activation induce striatal neuroprotection through a PI3K/Akt/mTORC1/BDNF pathway. <cite>Paper7</cite>
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| ===Social neuroscience of cannabis smoking===
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| * [https://www.mrnice.nl/forum/9-patients-forum/15834-why-do-you-smoke-marijuana.html Why do you smoke marijuana?]
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| ===Synaptic hypercomputation===
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| Biological utilization of quantum nonlocality in microtubules:
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| * [https://www.thenakedscientists.com/forum/index.php?topic=68596 Is synaptic hypercomputation a function of exocytosis?]
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| * [https://www.thenakedscientists.com/forum/index.php?topic=66293.0 Is quantum interference in brain activity possible?]
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| ===Ubiquity of consciousness===
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| * The brain is not the source of consciousness: http://www.tandfonline.com/doi/full/10.1080/19420889.2015.1085138
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| ** http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245704/
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| * Intrinsic awareness (IA); A machine has no internal purpose within. http://arxiv.org/abs/1101.2422
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| * [https://www.thenakedscientists.com/forum/index.php?topic=70173 Do all living cells have photonic protoconsciousness?]
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| ===References===
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| <biblio>
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| #Paper1 https://www.jstage.jst.go.jp/article/jts/36/3/36_3_267/_article
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| //Nasal instillation of nanoparticle-rich diesel exhaust particles slightly affects emotional behavior and learning capability in rats
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| #Paper2 https://www.ncbi.nlm.nih.gov/pubmed/16332990
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| //Delta9-tetrahydrocannabinol and endogenous cannabinoid anandamide directly potentiate the function of glycine receptors.
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| #Paper3 https://www.ncbi.nlm.nih.gov/pubmed/7514666
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| //Facilitatory effect of docosahexaenoic acid on N-methyl-D-aspartate response in pyramidal neurones of rat cerebral cortex.
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| #Paper4 https://www.ncbi.nlm.nih.gov/pubmed/25707796
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| //Hypothalamic POMC neurons promote cannabinoid-induced feeding.
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| #Paper5 https://www.ncbi.nlm.nih.gov/pubmed/19027757
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| //Caffeine drinking potentiates cannabinoid transmission in the striatum: interaction with stress effects.
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| #Paper6 https://www.ncbi.nlm.nih.gov/pubmed/23858446
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| //Cognitive abnormalities and hippocampal alterations in monoamine oxidase A and B knockout mice.
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| #Paper7 https://www.ncbi.nlm.nih.gov/pubmed/25698444
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| //The CB₁ cannabinoid receptor signals striatal neuroprotection via a PI3K/Akt/mTORC1/BDNF pathway.
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| #Paper8 https://www.ncbi.nlm.nih.gov/pubmed/7350652
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| //Dimethyl and monomethyl sulfate: presence in coal fly ash and airborne particulate matter.
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| #Paper9 http://particleandfibretoxicology.biomedcentral.com/articles/10.1186/1743-8977-2-10
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| //Combustion-derived nanoparticles: A review of their toxicology following inhalation exposure.
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| #Paper10 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617054/
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| //Fine particulate matter in acute exacerbation of COPD.
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| #Paper11 https://www.ncbi.nlm.nih.gov/pubmed/25171395
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| //Positive feedback loop of autocrine BDNF from microglia causes prolonged microglia activation.
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| #Paper12 http://pubs.rsc.org/en/content/articlelanding/2017/tx/c6tx00314a
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| //Synergistic effects of particulate matter (PM2.5) and sulfur dioxide (SO2) on neurodegeneration via the microRNA-mediated regulation of tau phosphorylation.
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| #Paper13 http://jaapl.org/content/35/4/469
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| //Amnesia and Crime.
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| #Paper14 http://journal.frontiersin.org/article/10.3389/fphar.2016.00355/full
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| //Splendor in the Grass? A Pilot Study Assessing the Impact of Medical Marijuana on Executive Function
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| #Paper15 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098150/
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| //Possible existence of optical communication channels in the brain
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| #Paper16 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653148/
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| //Endocannabinoid signaling mediates oxytocin-driven social reward
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| #Paper17 https://www.ncbi.nlm.nih.gov/pubmed/11826965
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| //Antihypertensive effects of acetic acid and vinegar on spontaneously hypertensive rats.
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| #Paper18 https://www.ncbi.nlm.nih.gov/pubmed/27264948
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| //Antipsychotic Induced Dopamine Supersensitivity Psychosis: A Comprehensive Review.
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| #Paper19 https://www.ncbi.nlm.nih.gov/pubmed/26419755
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| //Vitamin D deficiency and essential hypertension.
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| #Paper20 http://www.sciencedirect.com/science/article/pii/S2251729413000050
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| //Vitamin D as an effective treatment approach for drug abuse and addiction.
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| #Paper21 https://www.ncbi.nlm.nih.gov/pubmed/24739187
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| //The in vitro GcMAF effects on endocannabinoid system transcriptionomics, receptor formation, and cell activity of autism-derived macrophages.
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| </biblio>
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| ===See also===
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| * [https://www.thenakedscientists.com/forum/index.php?topic=65238 Is geoengineering destroying life?]
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| * [https://www.thenakedscientists.com/forum/index.php?topic=49418 What are the consequences of being sprayed with barium and aluminium?]
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| * [https://www.thenakedscientists.com/forum/index.php?topic=67517 Are drug nanoparticles harmful in the same way that pollutants are?]
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| * [https://www.thenakedscientists.com/forum/index.php?topic=69963.0 Effects of geoengineering on the limbic system]
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| * [https://www.thenakedscientists.com/forum/index.php?topic=70334.0 What is the role of radiative forcing in cloud physics?]
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