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===Microglial activation in the PFC===
* Activation of the microglia by aluminium oxide disrupt the cytokine/neurotrophin balance.
* Possible role of microglia-derived BDNF signaling on intracellular Ca2+ elevation? <cite>Paper11</cite>
 
===Nanotoxicity of fine particulate matter (PM2.5)===
* Fly-ash particulate matter includes:
** aluminium oxide
** silicon dioxide
** titanium dioxide
** barium oxide
** iron oxide
** cadmium
** arsenic
** dimethyl sulfate and monomethyl sulfate<cite>Paper8</cite>
* Exposure to coal fly ash is nanotoxic and may cause neuroinflammation via oxidative stress production. <cite>Paper9</cite>
* Coal fly ash is a source of particulate matter.
* Fine particulate matter (PM2.5) exposure may induce chronic COPD pathogenesis.<cite>Paper10</cite>
===Neurodiversity===
* [https://www.thenakedscientists.com/forum/index.php?topic=71002.0 Why is neurodiversity a controversial subject?]
===Phenomenology of consciousness===
The brain is not the source of consciousness:
* http://www.tandfonline.com/doi/full/10.1080/19420889.2015.1085138
* http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245704/
Intrinsic awareness (IA):
* A machine has no internal purpose within...
* http://arxiv.org/abs/1101.2422
Ubiquity of consciousness:
* [https://www.thenakedscientists.com/forum/index.php?topic=70173 Do all living cells have photonic protoconsciousness?]
 
===Political manipulations of psychiatry===
====Sluggish schizophrenia====
* Behaviors are not diseases.
* Schizophrenia definition is sluggish and discriminates neurological variations in the genome.
* [http://schizophreniabulletin.oxfordjournals.org/content/36/1/33.full Psychiatry as a means of intimidation.]
* [https://www.thenakedscientists.com/forum/index.php?topic=70401.0 Is schizophrenia caused by dopamine supersensitivity?]
 
===Retrograde signaling===
* [[User:Etienne_Robillard/Notebook/Endocannabinoids|Notebook]]
====Glycinergic neurotransmission trafficking====
<font color=red>Allosteric modulation of glycine receptors by endocannabinoids</font>
* THC and anandamide may modulates synaptogenesis in the retina and brain through glycinergic transmission <cite>Paper2</cite>
* Intracellular DHA delivery facilitate glutamatergic NMDA receptor function in the presence of glycine <cite>Paper3</cite>
* THC and anandamide enhance NMDA-dependent LTP through glycine receptor activation
====CB1-induced cholinergic neurotransmission====
* Hypothalamic POMC neurons promote CB1-induced feeding <cite>Paper4</cite>
* Adenosine antagonist (caffeine) potentiate corticostriatal neurotransmission (connectivity) through presynaptic CB1 receptor activation. <cite>Paper5</cite>
* Monoamine oxidase inhibition affects cannabinoid-induced synaptogenesis. <cite>Paper6</cite>
 
====Intracellular CB1/BDNF signaling====
* CB1 receptor activation may induce corticostriatal neuroprotection through a PI3K/Akt/mTORC1/BDNF pathway. <cite>Paper7</cite>
====Pineal gland====
* Dopamine receptors in the pineal gland may control melatonin production via anandamide trafficking? <cite>Paper25</cite><cite>Paper26</cite>
 
===Social neuroscience of cannabis smoking===
* [https://www.mrnice.nl/forum/9-patients-forum/15834-why-do-you-smoke-marijuana.html Why do you smoke marijuana?]
* [https://www.mrnice.nl/forum/9-patients-forum/15851-cannabis-lucid-dreaming-therapy.html Cannabis for lucid dreaming (LD) therapy?]
* [http://www.scienceforums.net/topic/104189-the-social-neuroscience-of-cannabis-smoking/ The social neuroscience of cannabis smoking]
 
===Synaptic hypercomputation===
* [[User:Etienne_Robillard/Notebook/Hypercomputation|Notebook]]
Biological utilization of quantum non-locality in microtubules:
* [https://www.thenakedscientists.com/forum/index.php?topic=68596 Is synaptic hypercomputation a function of exocytosis?]
* [https://www.thenakedscientists.com/forum/index.php?topic=66293.0 Is quantum interference in brain activity possible?]
Biophotonic non-locality of tubulin heterodimer:
* The non-local (quantum) nature of biophotonic energy may require ultra-fast optical communication channels in MTs to potentiate a presynaptic action potential into a visible waveform! (Reference needed)
* Is the tubulin dipole moment phase-dependent? (Reference needed)
 
 
====Phase coherence of synaptic hypercomputation====
Retrograde signaling and synaptogenesis:
* [https://www.thenakedscientists.com/forum/index.php?topic=67779 What is coherent synaptic transmission?]
* [https://www.thenakedscientists.com/forum/index.php?topic=70046.0 What is synaptic latency?]
 
===References===
<biblio>
#Paper1 https://www.jstage.jst.go.jp/article/jts/36/3/36_3_267/_article
//Nasal instillation of nanoparticle-rich diesel exhaust particles slightly affects emotional behavior and learning capability in rats
#Paper2 https://www.ncbi.nlm.nih.gov/pubmed/16332990
//Delta9-tetrahydrocannabinol and endogenous cannabinoid anandamide directly potentiate the function of glycine receptors.
#Paper3 https://www.ncbi.nlm.nih.gov/pubmed/7514666
//Facilitatory effect of docosahexaenoic acid on N-methyl-D-aspartate response in pyramidal neurones of rat cerebral cortex.
#Paper4 https://www.ncbi.nlm.nih.gov/pubmed/25707796
//Hypothalamic POMC neurons promote cannabinoid-induced feeding.
#Paper5 https://www.ncbi.nlm.nih.gov/pubmed/19027757
//Caffeine drinking potentiates cannabinoid transmission in the striatum: interaction with stress effects.
#Paper6 https://www.ncbi.nlm.nih.gov/pubmed/23858446
//Cognitive abnormalities and hippocampal alterations in monoamine oxidase A and B knockout mice.
#Paper7 https://www.ncbi.nlm.nih.gov/pubmed/25698444
//The CB₁ cannabinoid receptor signals striatal neuroprotection via a PI3K/Akt/mTORC1/BDNF pathway.
#Paper8 https://www.ncbi.nlm.nih.gov/pubmed/7350652
//Dimethyl and monomethyl sulfate: presence in coal fly ash and airborne particulate matter.
#Paper9 http://particleandfibretoxicology.biomedcentral.com/articles/10.1186/1743-8977-2-10
//Combustion-derived nanoparticles: A review of their toxicology following inhalation exposure.
#Paper10 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617054/
//Fine particulate matter in acute exacerbation of COPD.
#Paper11 https://www.ncbi.nlm.nih.gov/pubmed/25171395
//Positive feedback loop of autocrine BDNF from microglia causes prolonged microglia activation.
#Paper12 http://pubs.rsc.org/en/content/articlelanding/2017/tx/c6tx00314a
//Synergistic effects of particulate matter (PM2.5) and sulfur dioxide (SO2) on neurodegeneration via the microRNA-mediated regulation of tau phosphorylation.
#Paper13 http://jaapl.org/content/35/4/469
//Amnesia and Crime.
#Paper14 http://journal.frontiersin.org/article/10.3389/fphar.2016.00355/full
//Splendor in the Grass? A Pilot Study Assessing the Impact of Medical Marijuana on Executive Function
#Paper15 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098150/
//Possible existence of optical communication channels in the brain
#Paper16 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653148/
//Endocannabinoid signaling mediates oxytocin-driven social reward
#Paper17 https://www.ncbi.nlm.nih.gov/pubmed/11826965
//Antihypertensive effects of acetic acid and vinegar on spontaneously hypertensive rats.
#Paper18 https://www.ncbi.nlm.nih.gov/pubmed/27264948
//Antipsychotic Induced Dopamine Supersensitivity Psychosis: A Comprehensive Review.
#Paper19 https://www.ncbi.nlm.nih.gov/pubmed/26419755
//Vitamin D deficiency and essential hypertension.
#Paper20 http://www.sciencedirect.com/science/article/pii/S2251729413000050
//Vitamin D as an effective treatment approach for drug abuse and addiction.
#Paper21 https://www.ncbi.nlm.nih.gov/pubmed/24739187
//The in vitro GcMAF effects on endocannabinoid system transcriptionomics, receptor formation, and cell activity of autism-derived macrophages.
#Paper22 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266250/
//Potential of garlic (Allium sativum) in lowering high blood pressure: mechanisms of action and clinical relevance.
#Paper23 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783408/
//Psychosis and the Control of Lucid Dreaming.
#Paper24 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604174/
//Cannabis in the Treatment of Dystonia, Dyskinesias, and Tics.
#Paper25 https://www.ncbi.nlm.nih.gov/pubmed/18554250
//The rat pineal gland comprises an endocannabinoid system.
#Paper26 https://www.ncbi.nlm.nih.gov/pubmed/26061461
//Rhythmic control of endocannabinoids in the rat pineal gland.
#Paper27 https://www.ncbi.nlm.nih.gov/pubmed/17439547
//Melatonin as a potential antihypertensive treatment.
#Paper28 https://www.ncbi.nlm.nih.gov/pubmed/22527998
//Melatonin: an overlooked factor in schizophrenia and in the inhibition of anti-psychotic side effects.
#Paper29 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3955008/
//Multiple Mechanistically Distinct Modes of Endocannabinoid Mobilization at Central Amygdala Glutamatergic Synapses.
#Paper30 https://www.ncbi.nlm.nih.gov/pubmed/28240187
//The endocannabinoid system modulating levels of consciousness, emotions and likely dream contents.
#Paper31 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489624/
//Insights into plant consciousness from neuroscience, physics and mathematics: A role for quasicrystals?
#Paper31 https://www.researchgate.net/publication/285705600_Dreams_and_neuroholography_An_interdisciplinary_Interpretation_of_development_of_homeotherm_state_in_evolution
//Dreams and neuroholography: An interdisciplinary. Interpretation of development of homeotherm state in evolution
</biblio>
 
===See also===
* [https://www.thenakedscientists.com/forum/index.php?topic=65238 Is geoengineering destroying life?]
* [https://www.thenakedscientists.com/forum/index.php?topic=49418 What are the consequences of being sprayed with barium and aluminium?]
* [https://www.thenakedscientists.com/forum/index.php?topic=67517 Are drug nanoparticles harmful in the same way that pollutants are?]
* [https://www.thenakedscientists.com/forum/index.php?topic=69963.0 Effects of geoengineering on the limbic system]
* [https://www.thenakedscientists.com/forum/index.php?topic=70334.0 What is the role of radiative forcing in cloud physics?]
* [https://www.thenakedscientists.com/forum/index.php?topic=70477 Hyperdreaming]

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