User:Etienne Robillard/Notebook/Chemtrails911 notebook/Agent Ecoli:PhotoReceptorComponent

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Imidazole pornography: Nitrogenous-derived nerve gas agents linked as prime suspects in the spraying of experimental aerosols over unaware and disinformed Quebec population

A mental prison is still a prison: The Histamine H3 receptor is possibly implicated in neuronal failures from repeated Imidazole exposures

• Scoooby, Doo! Have you ever guessed why no one is looking up ?
• In Drosophilia (fruit flies), the histamine (h3) receptor is a cholinergic neurotransmitter implicated in PeRiPheral ViSion/EyE and in managing allergic reactions to name a few. 1.

"Histamine exerts its actions by combining with specific cellular histamine receptors. The four histamine receptors that have been discovered in humans are designated H1 through H4, and are all G protein-coupled receptors (GPCR). Histamine receptors in insects, like Drosophila melanogaster, are histamine-gated chloride channels that function in inhibition of neurons.6"

• Histamine H3-receptor inverse agonists as novel antipsychotics.
  • see also Histidine
    • and Imidazole-4-acetaldehyde, an endogenous heterocyclic amine implicated in Folate and Tryptophan biosynthesis.

Engineering Deceit with the Clouds: The H3 receptor site is an inducible metabolic promoter for orthogonal drug delivery and prokariotic gene regulation using Lactose derived repressors: An hypothesis....

• Must read! Histidine Metabolism (Serine/Threonine related?)
• Stress_induced_neuroinflammation_in_homo_sapiens: Are Excitoxins (ie: oxidative stress) implicated in bacterial transformations/NF/MRSA ? In this case Imidazole would be an effective fungicide to inhibit bacterial transformations.
• How can imidazole-derived homoserine transferase (HSL) be a reversible primer in circumstances where restriction enzymes are catalyzed using a thermo-regulated growing process to allow effective competent cells recombineering? (ie: cold ice ?)

Orthogonal adducts for stress induced MAP kinase phosphorylation: The future of mental esclavagism precedes us!

• Aspartate (D): a nonessential proteogenic known as aspartic acid found in diet soda drinks as a substitute for Glucose (-)
• Glutamate (E, Glu)

Repressing the Repressors: Standardizing the Genocide of America with Nitrogen-derived Nerve Gas Clouds.

List of receptor-associated promoter candidates for Imidazole-derived metabolic gene regulation in prokariotes organisms:

• Lactose (Lac operon): [1]
• Glucose (UTP?, PRPP?) -> UGT
• L-Arabinose (IPTG? WTF?! (Notice I am sober in the morning))
• notice they all ends with -ose prefix. :)
• http://en.wikipedia.org/wiki/Sorafenib : another tyrosine kinase inhibitor (TKI) drug with 2 symmetrical N atoms.
  • Inhibits the Ras/Raf/MEK (MAPK2) pathway from Bcl-2 derived protein (BAD) phosphorylation. (1)

Purine/pyrimidine analogs for de-novo Imidazole purification

• Principles of Biochemistry/Nucleic acid III: Synthesis of nucleotides
  • Notice: Further connections towards elucidating the metabolic regulation of Scooby Doo based restriction endonucleases suggests Imidazole may be synthetized with or without formaldehyde, thus supporting the hypothesis of Imidazole derived adducts as orthogonal nucleic acid inhibitors.
  • "What is a Purine? The name was invented by the German chemist Emil Fischer in 1884. A purine is a nucleotide (a nucleoside + phosphate group) that is amine based and planar, aromatic, and heterocyclic. The structure of purine is that of a cyclohexane(pyrimidine group) and cyclopentane(imidazole group) attached to one another; the Nitrogen atoms are at positions 1,3,7,9. Adenine(A) and Guanine(G) are examples of purines which are involved in the construction of the backbone of the DNA and RNA. They are also a part of the structures for Adenosine disphosphate (ADP), triphosphate(ATP), and other enzymes. Purines form bonds with pentoses exclusively through the 9th Nitrogen atom." 1
  • Degradation of Purines and Pyrimidines Leads to Uric Acid and Urea, Respectively

cAMP (Cyclic adenosine monophosphate) notes:

• "Role of cAMP in bacteria

In bacteria, the level of cAMP varies depending on the medium used for growth. In particular, cAMP is low when glucose is the carbon source. This occurs through inhibition of the cAMP-producing enzyme, adenylyl cyclase, as a side-effect of glucose transport into the cell. The transcription factor cAMP receptor protein (CRP) also called CAP (catabolite gene activator protein) forms a complex with cAMP and thereby is activated to bind to DNA. CRP-cAMP increases expression of a large number of genes, including some encoding enzymes that can supply energy independent of glucose.

cAMP, for example, is involved in the positive regulation of the lac operon. In an environment of a low glucose concentration, cAMP accumulates and binds to the allosteric site on CRP (cAMP receptor protein), a transcription activator protein. The protein assumes its active shape and binds to a specific site upstream of the lac promoter, making it easier for RNA polymerase to bind to the adjacent promoter to start transcription of the lac operon, increasing the rate of lac operon transcription. With a high glucose concentration, the cAMP concentration decreases, and the CRP disengages from the lac operon." 1

References

• V. Drugs That Effect Cholinergic Mechanisms (Part 2).
• WHAT IS NECROTIZING FASCIITIS (MRSA) AND WHY IS IT ON A RAMPAGE THROUGH TUCSON
• 2-Aminoimidazole-Derived Antibiofilm Agents
• Alzheimer’s Disease Histamine Therapy Research
• A new class of N-methyl-D-aspartic acid receptor agonists and antagonists--derivatives of imidazole-4,5- and pyrazole-3,4-dicarboxylic acids
• NMDA receptor: "Calcium flux through NMDARs is thought to be critical in synaptic plasticity, a cellular mechanism for learning and memory. The NMDA receptor is distinct in two ways: first, it is both ligand-gated and voltage-dependent; second, it requires co-activation by two ligands: glutamate and glycine.[7]"
  • Nmdar1 and Nmdar2

See also

Project Bioshield 2 stuff (BARDA):

• Never forget! http://www.illuminati-news.com/bush-scrutiny.htm
• Article on Jerome Hauer: http://www.fromthewilderness.com/free/ww3/121505_jerome_hauer.shtml
• http://www.democracynow.org/2005/11/10/germ_boys_and_yes_men_how
• http://www.newsfollowup.com/bioport.htm
• http://www.newsfollowup.com/carlyle.htm

Keywords

Alzheimer Disease, Alkyloids, Anthracyclines, Aspartame, Clozanpine, Cholinesterase, Doxorubicin, Excitoxicity, Endocytosis, Endonucleases, Glutamate, Glucose, Histidine, Imidazole, NMDAR (N-methyl-D-aspartate Receptor), mGluR, MAPK2 (MEK), MRSA, Pyrimidine, Purines, Proline, Proteases, Uric acid, Schizophrenia, Serine, Synthetic Biology, Synthetic Recombineering, Stereochemistry

In Science We Trust.

"If a man wishes to rid himself of a feeling of unbearable oppression, he may have to take hashish." -Friedrich Nietzsche

"They must find it difficult...Those who have taken authority as the truth, rather than truth as the authority."-Gerald Massey

"Modern warfare is in every respect so horrifying, that scientific people will only regret that it draws its means from the progress of the sciences. I hope that the present war [World War I] will teach the peoples of Europe a lasting lesson and bring the friends of peace into power. Otherwise the present ruling classes will really deserve to be swept away by socialism." -Emil Fischer