User:Tkadm30/Notebook/Endocannabinoids
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Creating anandamide ligands with polyunsaturated fatty acids and cannabinoids (THC)
Experiment
- Observe the properties and chemical reactions of hydrolysis of anandamide ligands in situ.
- measure blah blah blah
Design
- Use omega 3 (DHA) fatty acids as substrate for anandamide hydrolysis
- Protect the hippocampus and neurons from stress induced damage.
Documentation
Protocol:
- http://www.ncbi.nlm.nih.gov/pubmed/23103355
- http://www.ncbi.nlm.nih.gov/pubmed/11470906
- http://www.ncbi.nlm.nih.gov/pubmed/9842734/
CB1 signaling and memory:
- http://www.ncbi.nlm.nih.gov/pubmed/24648181
- Cannabinoids and hippocampal neurogenesis:
Anandamide signaling:
FAAH (fatty acid amide hydrolase):
Introduction to fatty amides: