User:Tkadm30/Notebook/Endocannabinoids/2-AG: Difference between revisions
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===Synopsis=== | ===Synopsis=== | ||
* A novel gliotransmitter controlled by the P2X7 receptor; | * A novel purinergic gliotransmitter controlled by the P2X7 receptor; | ||
* 2-AG is an | * 2-AG is an endocannabinoid ligand synthesized by diacylglycerol lipase (DGL-α) and phospholipase C (PLC). | ||
===Notes=== | ===Notes=== | ||
Revision as of 05:00, 14 January 2017
2-arachidonoylglycerol (2-AG)
Synopsis
- A novel purinergic gliotransmitter controlled by the P2X7 receptor;
- 2-AG is an endocannabinoid ligand synthesized by diacylglycerol lipase (DGL-α) and phospholipase C (PLC).
Notes
- Astrocytes-induced synaptogenesis is enhanced by synaptic retrograde signaling.
- 2-AG synthesis is dependent on arachidonic acid and PLC.
- 2-AG exert neuroprotective effects on excitotoxic brain injury.
