User:Tkadm30/Notebook/Endocannabinoids/2-AG: Difference between revisions
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===Notes=== | ===Notes=== | ||
Astrocytes-induced synaptogenesis is enhanced by synaptic retrograde signaling. | * Astrocytes-induced synaptogenesis is enhanced by synaptic retrograde signaling. | ||
* 2-AG synthesis is dependent on arachidonic acid and PLC. | |||
===Results=== | ===Results=== | ||
Revision as of 03:50, 7 November 2016
2-arachidonoylglycerol (2-AG)
Synopsis
A novel gliotransmitter controlled by the P2X7 receptor;
2-AG is an endogenous cannabinoid ligand synthesized by diacylglycerol lipase (DGL-α) and phospholipase C (PLC).
Notes
- Astrocytes-induced synaptogenesis is enhanced by synaptic retrograde signaling.
- 2-AG synthesis is dependent on arachidonic acid and PLC.
Results
2-AG exert neuroprotective effects on excitotoxic brain injury.
